Gene Information gene info

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GENE：QARS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol QARS1
FullNmae glutaminyl-tRNA synthetase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9751
EnsembleID ENSG00000172053
Uniprot P47897

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
QARS1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
QARS1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
QARS1 GO:0004819,GO:0004819,GO:0004819,GO:0004860,GO:0005515,GO:0005524,GO:0005737,GO:0005759,GO:0005829,GO:0005829,GO:0005829,GO:0006418,GO:0006425,GO:0006425,GO:0006469,GO:0007420,GO:0017101,GO:0017101,GO:0019901,GO:0032873,GO:0032991,GO:0045892,GO:2001234

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
QARS1 hsa:5859 path:hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human)
QARS1 hsa:5859 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLE5 QARS1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 QARS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 QARS1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 QARS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 QARS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS QARS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 QARS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR QARS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 QARS1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 QARS1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EC1BE QARS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C QARS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA QARS1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXLNA QARS1 25348397 N/A physical interaction ComPPI
MAPRE1 QARS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBSL QARS1 25348397 N/A physical interaction ComPPI
AIMP2 QARS1 21285945 24234451 25348397 colocalization cosedimentation,physical interaction,fluorescence microscopy ComPPI,IntAct
TTR QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SORBS3 QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LZTS2 QARS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDKN1A QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMC6 QARS1 25348397 N/A physical interaction ComPPI
EDC3 QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TK1 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF2B2 QARS1 25348397 N/A physical interaction ComPPI
FOXB1 QARS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
XIAP QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KEAP1 QARS1 25348397 N/A physical interaction ComPPI
MCM2 QARS1 25348397 N/A physical interaction ComPPI
SF3B4 QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMN1 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DPPA4 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VBP1 QARS1 25348397 N/A physical interaction ComPPI
DDX17 QARS1 25348397 N/A physical interaction ComPPI
VPS37B QARS1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPL10 QARS1 25348397 N/A physical interaction ComPPI
SPRED2 QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN QARS1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX9 QARS1 25348397 N/A physical interaction ComPPI
EIF4G1 QARS1 25348397 N/A physical interaction ComPPI
GSK3B QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CUL3 QARS1 25348397 N/A physical interaction ComPPI
PPM1A QARS1 25348397 N/A physical interaction ComPPI
PIK3R3 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DLD QARS1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSP90AA1 QARS1 10913161 24234451 25348397 physical association two hybrid ComPPI,IntAct
NTRK1 QARS1 25348397 N/A physical interaction ComPPI
SMAD9 QARS1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAP3K5 QARS1 11096076 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LAMTOR3 QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLEC QARS1 25348397 N/A physical interaction ComPPI
HMG20A QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IQGAP1 QARS1 25348397 N/A physical interaction ComPPI
PRRC2A QARS1 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CFTR QARS1 25348397 N/A physical interaction ComPPI
EIF2S1 QARS1 25348397 N/A physical interaction ComPPI
ACTN2 QARS1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SDCBP QARS1 25348397 N/A physical interaction ComPPI
EPRS1 QARS1 25348397 N/A physical interaction ComPPI
RARS1 QARS1 10801842 14525934 22863883 22939629 25348397 26344197 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
QARS1 ASL 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
QARS1 TRAF2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
QARS1 DUSP11 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QARS1 CPNE3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QARS1 RNF11 14525934 15231748 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
QARS1 HDAC5 25348397 N/A physical interaction ComPPI
QARS1 KCNE3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 CDK4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 STK3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 TSC22D1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 GADD45A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 CDK2 25348397 N/A physical interaction ComPPI
QARS1 CUL1 25348397 N/A physical interaction ComPPI
QARS1 APP 25348397 N/A physical interaction ComPPI
QARS1 AIMP1 25348397 N/A physical interaction ComPPI
QARS1 IARS1 25348397 N/A physical interaction ComPPI
QARS1 KARS1 25348397 N/A physical interaction ComPPI
QARS1 LARS1 25348397 N/A physical interaction ComPPI
QARS1 DARS1 25348397 N/A physical interaction ComPPI
QARS1 MARS1 25348397 N/A physical interaction ComPPI
QARS1 EEF1E1 25348397 N/A physical interaction ComPPI
QARS1 GARS1 25348397 N/A physical interaction ComPPI
QARS1 UBA1 25348397 N/A physical interaction ComPPI
QARS1 TRMT1 25348397 N/A physical interaction ComPPI
QARS1 MRPS18B 25348397 N/A physical interaction ComPPI
QARS1 MRPS22 25348397 N/A physical interaction ComPPI
QARS1 AARS1 25348397 N/A physical interaction ComPPI
QARS1 ZFR 25348397 N/A physical interaction ComPPI
QARS1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
QARS1 CLTC 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 IRF1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
QARS1 SAV1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
QARS1 EIF2S3 25348397 N/A physical interaction ComPPI
QARS1 EIF2S3B 25348397 N/A physical interaction ComPPI
QARS1 HNRNPA1 25348397 N/A physical interaction ComPPI
QARS1 HNRNPA2B1 25348397 N/A physical interaction ComPPI
QARS1 IGF2BP3 25348397 N/A physical interaction ComPPI
QARS1 CCAR2 25348397 N/A physical interaction ComPPI
QARS1 MRE11 25348397 N/A physical interaction ComPPI
QARS1 NMT1 25348397 N/A physical interaction ComPPI
QARS1 PTBP1 25348397 N/A physical interaction ComPPI
QARS1 RTCB 25348397 N/A physical interaction ComPPI
QARS1 DDX1 25348397 N/A physical interaction ComPPI
QARS1 DNAJA1 25348397 N/A physical interaction ComPPI
QARS1 EIF2B3 25348397 N/A physical interaction ComPPI
QARS1 RFC4 25348397 N/A physical interaction ComPPI
QARS1 RPL13 25348397 N/A physical interaction ComPPI
QARS1 RPL15 25348397 N/A physical interaction ComPPI
QARS1 RPL19 25348397 N/A physical interaction ComPPI
QARS1 RPL23A 25348397 N/A physical interaction ComPPI
QARS1 RPL26L1 25348397 N/A physical interaction ComPPI
QARS1 RPL27 25348397 N/A physical interaction ComPPI
QARS1 RPL27A 25348397 N/A physical interaction ComPPI
QARS1 RPL36 25348397 N/A physical interaction ComPPI
QARS1 RPL7A 25348397 N/A physical interaction ComPPI
QARS1 RPLP0 25348397 N/A physical interaction ComPPI
QARS1 RPLP0P6 25348397 N/A physical interaction ComPPI
QARS1 TUBB2A 25348397 N/A physical interaction ComPPI
QARS1 VARS1 25348397 N/A physical interaction ComPPI
QARS1 STAU1 25348397 N/A physical interaction ComPPI
QARS1 HUWE1 25348397 N/A physical interaction ComPPI
QARS1 TLE5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QARS1 TCF12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QARS1 TRIP13 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QARS1 TRAF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QARS1 DTX2 25348397 N/A physical interaction ComPPI
QARS1 KLC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QARS1 MOV10 25348397 N/A physical interaction ComPPI
QARS1 NXF1 25348397 N/A physical interaction ComPPI
QARS1 CUL7 25348397 N/A physical interaction ComPPI
QARS1 CCDC8 25348397 N/A physical interaction ComPPI
QARS1 RNF2 25348397 N/A physical interaction ComPPI
QARS1 KCMF1 25348397 N/A physical interaction ComPPI
QARS1 ASNS 25348397 N/A physical interaction ComPPI
QARS1 ATP1B3 25348397 N/A physical interaction ComPPI
QARS1 CBS 25348397 N/A physical interaction ComPPI
QARS1 TOMM40 25348397 N/A physical interaction ComPPI
QARS1 TRMT6 25348397 N/A physical interaction ComPPI
QARS1 XRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
QARS1 FOXM1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
QARS1 RNF126 25348397 N/A physical interaction ComPPI
QARS1 SENP3 25348397 N/A physical interaction ComPPI
QARS1 NLGN3 25348397 N/A physical interaction ComPPI
QARS1 C1ORF131 25348397 N/A physical interaction ComPPI
QARS1 OFD1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
QARS1 CYLD 25348397 N/A physical interaction ComPPI
QARS1 BRCA1 25348397 N/A physical interaction ComPPI
QARS1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
QARS1 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
QARS1 BAG2 18457437 24234451 25348397 association tandem affinity purification ComPPI,IntAct
QARS1 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
QARS1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
QARS1 ESS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 MESD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 TADA2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 GSTZ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 BIRC7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 USHBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 NAB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 FAM83A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 DNM2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 NEBL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 LGALS9B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 FAM161A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 GPBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 TRIM27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 NFKBID 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 SPDYE4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 COG6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 ZRANB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 DMBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 HES7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 LZTS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 SP7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 PRDM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 EFHC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 CALCOCO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 B9D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 SHLD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 TGM7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QARS1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
MAP3K14 QARS1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IK QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM118B QARS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MRPS23 QARS1 25348397 N/A physical interaction ComPPI

Visualization










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