Gene Information gene info

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GENE：RHOT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RHOT2
FullNmae ras homolog family member T2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21169
EnsembleID ENSG00000140983
Uniprot Q8IXI1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RHOT2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RHOT2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RHOT2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RHOT2 GO:0003924,GO:0005509,GO:0005515,GO:0005525,GO:0005739,GO:0005741,GO:0005741,GO:0005741,GO:0007005,GO:0007015,GO:0007165,GO:0007264,GO:0016020,GO:0019725,GO:0047497,GO:0047497,GO:0097345

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RHOT2 hsa:89941 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 RHOT2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RHOT2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 RHOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000512C88 RHOT2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAD2L2 RHOT2 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL9 RHOT2 25348397 N/A physical interaction ComPPI
ZFYVE9 RHOT2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TOMM22 RHOT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPS26 RHOT2 25348397 N/A physical interaction ComPPI
SLC38A1 RHOT2 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
SAMM50 RHOT2 25348397 N/A physical interaction ComPPI
DHX9 RHOT2 25348397 N/A physical interaction ComPPI
RHOT2 RYK 25348397 N/A physical interaction ComPPI
RHOT2 PRKN 25348397 N/A physical interaction ComPPI
RHOT2 ACIN1 25348397 N/A physical interaction ComPPI
RHOT2 TECR 25348397 N/A physical interaction ComPPI
RHOT2 RAB5A 25348397 N/A physical interaction ComPPI
RHOT2 OXA1L 25348397 N/A physical interaction ComPPI
RHOT2 NDUFS7 25348397 N/A physical interaction ComPPI
RHOT2 SRSF5 25348397 N/A physical interaction ComPPI
RHOT2 RPS2 25348397 N/A physical interaction ComPPI
RHOT2 HNRNPR 25348397 N/A physical interaction ComPPI
RHOT2 CHCHD4 25348397 N/A physical interaction ComPPI
RHOT2 EEF2 25348397 N/A physical interaction ComPPI
RHOT2 NDUFS8 25348397 N/A physical interaction ComPPI
RHOT2 NDUFS1 25348397 N/A physical interaction ComPPI
RHOT2 FBXO6 25348397 N/A physical interaction ComPPI
RHOT2 ILK 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RHOT2 PINK1 25348397 N/A physical interaction ComPPI
RHOT2 RNF2 25348397 N/A physical interaction ComPPI
RHOT2 NTRK1 25348397 N/A physical interaction ComPPI
RHOT2 MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RHOT2 COQ9 25348397 N/A physical interaction ComPPI
RHOT2 UBC 25348397 N/A physical interaction ComPPI
RHOT2 MRPL20 25348397 N/A physical interaction ComPPI
RHOT2 RHOT1 25348397 N/A physical interaction ComPPI
RHOT2 SARM1 25348397 N/A physical interaction ComPPI
RHOT2 XPR1 25348397 N/A physical interaction ComPPI
RHOT2 FKRP 25348397 N/A physical interaction ComPPI
RHOT2 WDFY3 25348397 N/A physical interaction ComPPI
RHOT2 ATP2B2 25348397 N/A physical interaction ComPPI
RHOT2 BTAF1 25348397 N/A physical interaction ComPPI
RHOT2 SGPP1 25348397 N/A physical interaction ComPPI
RHOT2 TRIM25 25348397 N/A physical interaction ComPPI
RHOT2 TRAK1 16630562 24234451 24995978 25348397 colocalization,physical association anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
RHOT2 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
RHOT2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RHOT2 SAR1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOT2 TMEM14B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOT2 PTPN5 24234451 25348397 28330616 association pull down ComPPI,IntAct
RHOT2 AIFM1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
RHOT2 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RHOT2 TOMM20 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RHOT2 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPF RHOT2 25348397 N/A physical interaction ComPPI
EIF4A3 RHOT2 25348397 N/A physical interaction ComPPI
PLGRKT RHOT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 RHOT2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB RHOT2 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B693E RHOT2 27087310 direct interaction,inhibition N/A NPInter

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