GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
RNF186
FullNmae
ring finger protein 186
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:25978
EnsembleID
ENSG00000178828
Uniprot
Q9NXI6
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
RNF186
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
RNF186
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
RNF186
GO:0004842,GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0031625,GO:0035519,GO:0035519,GO:0043161,GO:0043161,GO:0046872,GO:0051865,GO:0051865,GO:0061630,GO:0061630,GO:0070059,GO:0070059,GO:0070534,GO:0070534,GO:0070585,GO:0070585,GO:2000785
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
E2F4
RNF186
17531812
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
YBX1
RNF186
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
PRDM14
RNF186
18971253
20953172
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
CTCF
RNF186
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
RNF186
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
RNF186
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000237AF9
RNF186
18185580
25416803
mrna cleavage,inhibition
array technology
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
UBE2D2
RNF186
19690564
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
UBE2H
RNF186
19690564
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
Visualization