GENE:RNF34
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RNF34 |
| FullNmae | ring finger protein 34 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17297 |
| EnsembleID | ENSG00000170633 |
| Uniprot | Q969K3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RNF34 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| RNF34 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RNF34 | GO:0002039,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0006511,GO:0006915,GO:0012505,GO:0016567,GO:0016567,GO:0016604,GO:0016607,GO:0031625,GO:0035872,GO:0043161,GO:0043161,GO:0043161,GO:0046872,GO:0061630,GO:0061630,GO:0061630,GO:0061630,GO:0070417,GO:0070936,GO:0070936,GO:1901796,GO:1901797,GO:1901981,GO:1902042,GO:1902042,GO:2000374,GO:2001271,GO:2001271 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | RNF34 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | RNF34 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | RNF34 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | RNF34 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RNF34 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RNF34 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RNF34 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RNF34 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000DDD35 | RNF34 | 20371350 23313552 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS00002152A8 | RNF34 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000075AB14 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FB065 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | RNF34 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HSPA8 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| HSPA2 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| SH3KBP1 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| CASP9 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| APPBP2 | RNF34 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| UNC119 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| FZR1 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D2 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| PPARGC1A | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | RNF34 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| SERPINB13 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| CASP8 | RNF34 | 15069192 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
| DNAJA3 | RNF34 | 12118383 14525934 25348397 27898060 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
| TRIM23 | RNF34 | 22493164 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CDC20 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| CASP10 | RNF34 | 15069192 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| UBA1 | RNF34 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| TRIM25 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| NOD1 | RNF34 | 25012219 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| UBE2H | RNF34 | 19549727 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| UBE2V1 | RNF34 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| ANAPC2 | RNF34 | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | UBE2F | 19549727 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RNF34 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | APP | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | PHF7 | 22493164 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RNF34 | RFFL | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | UNC119B | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | EFCAB7 | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | KLHL15 | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | MANSC1 | 25348397 | N/A | physical interaction | ComPPI |
| RNF34 | TSR3 | 25348397 | N/A | physical interaction | ComPPI |
