Gene Information gene info

GENE:RTKN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RTKN2
FullNmae rhotekin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19364
EnsembleID ENSG00000182010
Uniprot Q8IZC4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RTKN2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RTKN2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RTKN2 GO:0005634,GO:0005737,GO:0005886,GO:0007165,GO:0008284,GO:0030097,GO:0051092,GO:1901224,GO:2001243

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RTKN2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 RTKN2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 RTKN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RTKN2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RTKN2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RTKN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 RTKN2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 RTKN2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 RTKN2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001A7F58 RTKN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 RTKN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 RTKN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075B0F6 RTKN2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SH3KBP1 RTKN2 25348397 N/A physical interaction ComPPI
IGHG1 RTKN2 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN1 RTKN2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RHOC RTKN2 25348397 N/A physical interaction ComPPI
BRCA1 RTKN2 25348397 N/A physical interaction ComPPI
PACSIN2 RTKN2 25348397 N/A physical interaction ComPPI

Visualization