Gene Information gene info

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GENE：SCG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SCG2
FullNmae secretogranin II
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10575
EnsembleID ENSG00000171951
Uniprot P13521

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SCG2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SCG2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SCG2 GO:0000165,GO:0001525,GO:0001525,GO:0001937,GO:0001938,GO:0005125,GO:0005125,GO:0005515,GO:0005615,GO:0005615,GO:0005788,GO:0006954,GO:0009306,GO:0030141,GO:0035556,GO:0042056,GO:0042056,GO:0043542,GO:0048245,GO:0048245,GO:0050918,GO:0050930,GO:0098992,GO:2000352,GO:2001237

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SCG2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP53 SCG2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SCG2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SCG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 SCG2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
FANCD2 SCG2 25361965 interaction type N/A PTMCode2
SCG2 FANCD2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SCG2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SCG2 COPS6 25348397 N/A physical interaction ComPPI
SCG2 TUBB4B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SCG2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCG2 UBQLN1 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SCG2 PIK3R1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SCG2 TNF 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SCG2 SCHIP1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PLEC SCG2 24234451 30021884 physical association cross-linking study IntAct
GNRHR SCG2 12581877 27898060 stimulant N/A OmniPath

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