GENE:SELENOS
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SELENOS |
| FullNmae | selenoprotein S |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30396 |
| EnsembleID | ENSG00000131871 |
| Uniprot | Q9BQE4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SELENOS | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SELENOS | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SELENOS | GO:0002865,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0005789,GO:0005881,GO:0005886,GO:0006111,GO:0006983,GO:0006983,GO:0009749,GO:0016209,GO:0019899,GO:0030433,GO:0030433,GO:0030968,GO:0030968,GO:0030970,GO:0030970,GO:0032715,GO:0032720,GO:0032869,GO:0034361,GO:0034362,GO:0034599,GO:0036502,GO:0036502,GO:0036513,GO:0036513,GO:0038023,GO:0045184,GO:0045454,GO:0045719,GO:0046325,GO:0050728,GO:0051117,GO:0051771,GO:0051775,GO:0071222,GO:0080164,GO:0098869,GO:1902236,GO:1990381,GO:2000110 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SELENOS | hsa:55829 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SELENOS | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SELENOS | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SELENOS | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000032015F | SELENOS | 20371350 22012620 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | SELENOS | 20371350 21572407 22012620 23313552 24906430 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | SELENOS | 19536157 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | SELENOS | 20371350 21572407 22012620 23313552 24906430 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000008C563 | SELENOS | 19536157 20371350 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E99CB | SELENOS | 19536157 20371350 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004A9320 | SELENOS | 19536157 20371350 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VCP | SELENOS | 14525934 15215856 16289116 17872946 18199748 21832065 22119785 24424410 24700463 25008318 25348397 27898060 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD,OmniPath |
| DERL2 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| KPNB1 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| CKAP4 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| CAV1 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| SYVN1 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| HSPA4 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| PTGS2 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| SNTG2 | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| SRPK2 | SELENOS | 23602568 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
| AMFR | SELENOS | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | DERL1 | 14525934 15215856 24234451 25348397 | colocalization,association | anti bait coimmunoprecipitation,classical fluorescence spectroscopy,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| SELENOS | SAA2 | 25348397 | N/A | two hybrid,physical interaction,in vitro | ComPPI |
| SELENOS | UFD1 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | SVIP | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | NPLOC4 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | HERPUD1 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | APOB | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | SELENOK | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | KLHDC2 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | UBXN8 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | UBE4A | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | FAF2 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | TMEM129 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | GTF2IRD1 | 25348397 | N/A | physical interaction | ComPPI |
| SELENOS | APOA5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SELENOS | MFHAS1 | 24234451 25348397 29513927 | N/A | protein array | ComPPI,IntAct |
| SELENOS | SAA1 | 12031974 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
