Gene Information gene info

  1. Home

GENE：SEPTIN4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SEPTIN4
FullNmae septin 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9165
EnsembleID ENSG00000108387
Uniprot O43236

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SEPTIN4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SEPTIN4 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SEPTIN4 GO:0000287,GO:0001764,GO:0003924,GO:0003924,GO:0005198,GO:0005515,GO:0005525,GO:0005634,GO:0005654,GO:0005739,GO:0005739,GO:0005741,GO:0005829,GO:0005940,GO:0006915,GO:0008021,GO:0015630,GO:0017157,GO:0030317,GO:0030424,GO:0030425,GO:0031105,GO:0031105,GO:0031105,GO:0031398,GO:0032153,GO:0042802,GO:0042981,GO:0043065,GO:0043204,GO:0048515,GO:0060090,GO:0061484,GO:0061640,GO:0097227,GO:0097227,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SEPTIN4 hsa:5414 path:hsa04210 Apoptosis - Homo sapiens (human)
SEPTIN4 hsa:5414 path:hsa04215 Apoptosis - multiple species - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SEPTIN4 XIAP 15029247 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR SEPTIN4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SP1 SEPTIN4 25790304 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SEPTIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SEPTIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SEPTIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SEPTIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SEPTIN4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 SEPTIN4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000381CEC SEPTIN4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E SEPTIN4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 SEPTIN4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 SEPTIN4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003804D8 SEPTIN4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A6D0C SEPTIN4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004407DC SEPTIN4 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DYNLL1 SEPTIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 SEPTIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XIAP SEPTIN4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RB1 SEPTIN4 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SIAH1 SEPTIN4 21185211 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC SEPTIN4 25348397 N/A physical interaction ComPPI
TNIK SEPTIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SEPTIN2 SEPTIN4 25348397 N/A physical interaction ComPPI
SEPTIN5 SEPTIN4 14525934 15214843 25348397 27898060 N/A two hybrid,two hybrid ComPPI,HPRD,OmniPath
NR4A1 SEPTIN4 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SNCAIP SEPTIN4 12695511 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BCL2 SEPTIN4 25348397 N/A physical interaction ComPPI
PRKN SEPTIN4 14525934 14559152 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SNCA SEPTIN4 25348397 N/A physical interaction ComPPI
BIRC3 SEPTIN4 25348397 N/A physical interaction ComPPI
SNCB SEPTIN4 12695511 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SEPTIN4 SEPTIN8 14525934 15116257 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SEPTIN4 AREL1 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN12 24234451 25348397 25588830 25775403 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,fluorescence microscopy ComPPI,IntAct
SEPTIN4 CDC42EP4 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN3 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN1 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN6 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN11 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN7 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN10 25348397 N/A physical interaction ComPPI
SEPTIN4 SEPTIN14 17922164 24234451 25348397 physical association two hybrid ComPPI,IntAct
SEPTIN4 SEPTIN4 14525934 15214843 N/A two hybrid HPRD

Visualization










  Return