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GENE：SIAH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SIAH1
FullNmae siah E3 ubiquitin protein ligase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10857
EnsembleID ENSG00000196470
Uniprot Q8IUQ4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SIAH1 pyroptosis 38842203 SIAH1 promoted the ubiquitination of 1κВ-α and activated nuclear factor kappa В (NF-κВ) signaling, which promoted the pyroptosis of cardiomyocytes. retulator signature
SIAH1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SIAH1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SIAH1 GO:0004842,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006511,GO:0006511,GO:0006915,GO:0007049,GO:0007283,GO:0007399,GO:0007411,GO:0008270,GO:0008270,GO:0009653,GO:0016567,GO:0030163,GO:0030877,GO:0031624,GO:0042802,GO:0043065,GO:0043161,GO:0043161,GO:0043161,GO:0043161,GO:0051402,GO:0060070,GO:0061630,GO:0061630,GO:0061630,GO:1990000,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SIAH1 hsa:6477 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
SIAH1 hsa:6477 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
SIAH1 hsa:6477 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
SIAH1 hsa:6477 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SIAH1 SIAH2 16899216 23180781 physical association anti tag coimmunoprecipitation InnateDB
SNCA SIAH1 18070888 23180781 ubiquitination reaction enzymatic study InnateDB
SIAH1 SNCAIP 15064394 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,pull down,enzymatic study InnateDB
SIAH1 UBE2D2 15064394 23180781 ubiquitination reaction enzymatic study InnateDB
MYD88 SIAH1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
AQP1 SIAH1 23180781 25416956 physical association two hybrid InnateDB
TRIM23 SIAH1 23180781 25416956 physical association two hybrid InnateDB
BCL6 SIAH1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SIAH1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SIAH1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SIAH1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SIAH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EHMT2 SIAH1 21847359 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SIAH1 20421190 trascriptional regulation,stimulation inferred by curator TFlink
SP1 SIAH1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F0F49 SIAH1 21062812 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS00000F0F49 SIAH1 21062812 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000017EA6A SIAH1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000004203C SIAH1 25416803 27377268 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase
URS000008F0CF SIAH1 25416803 25851994 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ATR SIAH1 22135298 phosphorylation N/A PhosphoSite
ATM SIAH1 22135298 phosphorylation N/A PhosphoSite
APC SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 APC 25361965 interaction type N/A PTMCode2
SIAH1 CACYBP 25361965 interaction type N/A PTMCode2
CACYBP SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 DAB1 25361965 interaction type N/A PTMCode2
DAB1 SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 DCC 25361965 interaction type N/A PTMCode2
DCC SIAH1 25361965 interaction type N/A PTMCode2
KHDRBS3 SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 KHDRBS3 25361965 interaction type N/A PTMCode2
RBBP8 SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 RBBP8 25361965 interaction type N/A PTMCode2
SH3RF1 SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 SH3RF1 25361965 interaction type N/A PTMCode2
TBL1X SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 TBL1X 25361965 interaction type N/A PTMCode2
NUMB SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 NUMB 25361965 interaction type N/A PTMCode2
POU2AF1 SIAH1 25361965 interaction type N/A PTMCode2
SIAH1 POU2AF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TBC1D22B SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PIAS2 SIAH1 25348397 N/A physical interaction ComPPI
UBE2I SIAH1 25348397 N/A physical interaction ComPPI
FAM90A1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAB33A SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
QRICH1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NPM1 SIAH1 25348397 N/A physical interaction ComPPI
RARA SIAH1 25348397 N/A physical interaction ComPPI
PSMC6 SIAH1 25348397 N/A physical interaction ComPPI
TRIB3 SIAH1 25348397 N/A physical interaction ComPPI
NECTIN2 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MOB3C SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LMNA SIAH1 25348397 N/A physical interaction ComPPI
UXT SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRR20E SIAH1 25348397 N/A physical interaction ComPPI
PRR20C SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRR20D SIAH1 25348397 N/A physical interaction ComPPI
XIAP SIAH1 21185211 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2D1 SIAH1 11389839 14525934 19549727 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro ComPPI,HPRD,IntAct
TP53BP2 SIAH1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZNF512B SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MCM2 SIAH1 25348397 N/A physical interaction ComPPI
CDK5R1 SIAH1 25348397 N/A physical interaction ComPPI
PHC2 SIAH1 20471960 21516116 21988832 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
UBE2E2 SIAH1 25348397 N/A physical interaction ComPPI
UBE2E3 SIAH1 25348397 N/A physical interaction ComPPI
UBE2D4 SIAH1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KATNAL1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
H4C1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VAV1 SIAH1 25348397 N/A physical interaction ComPPI
SIAH2 SIAH1 16899216 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FLI1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COPS5 SIAH1 25348397 N/A physical interaction ComPPI
PIAS1 SIAH1 25348397 N/A physical interaction ComPPI
OPRK1 SIAH1 23840749 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OPRD1 SIAH1 25348397 N/A physical interaction ComPPI
OPRM1 SIAH1 23840749 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
UBE2D2 SIAH1 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIAH1 APC 11389840 14525934 24234451 25241761 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
SIAH1 TUBA4A 11146551 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SIAH1 SYP 11786535 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SIAH1 POU2AF1 11483517 11483518 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SIAH1 PEG3 10681424 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
SIAH1 BAG1 12421809 25348397 27898060 9582267 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
SIAH1 TUBA1A 11146551 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SIAH1 TUBA1B 11146551 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SIAH1 KIF22 11146551 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SIAH1 DAB1 12646221 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SIAH1 NUMB 11752454 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SIAH1 EIF3J 14525934 25348397 9822659 N/A experimental interaction detection,in vivo ComPPI,HPRD
SIAH1 TUBA8 11146551 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SIAH1 SLC9A3R2 12421809 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
SIAH1 CACYBP 11389839 12421809 12626763 14525934 16085652 16713569 20181957 22295074 23208506 24234451 25241761 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct,OmniPath
SIAH1 KHDRBS3 14525934 15163637 16189514 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
SIAH1 PEG10 12810624 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SIAH1 SNCAIP 14506261 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SIAH1 AFF4 14525934 15459319 16189514 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
SIAH1 DCC 14525934 25348397 9858595 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIAH1 SH3RF1 14525934 16230351 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SIAH1 AFF1 14525934 15221006 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SIAH1 RBBP8 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
SIAH1 PKD1 14525934 15284290 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
SIAH1 GAPDH 14525934 15951807 22534308 23027902 25348397 25391652 26438826 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SIAH1 HIPK3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SIAH1 TBL1X 25348397 N/A physical interaction ComPPI
SIAH1 HIF1AN 25348397 N/A physical interaction ComPPI
SIAH1 PIAS3 25348397 N/A physical interaction ComPPI
SIAH1 UBE2D3 17420721 19250734 19549727 19690564 22483617 24234451 25348397 27898060 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct,OmniPath
SIAH1 UBE2N 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIAH1 UBE2K 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIAH1 RUNX1 25348397 N/A physical interaction ComPPI
SIAH1 RLIM 25348397 N/A physical interaction ComPPI
SIAH1 UBE2L6 25348397 N/A physical interaction ComPPI
SIAH1 PML 25348397 N/A physical interaction ComPPI
SIAH1 PLCE1 25348397 N/A physical interaction ComPPI
SIAH1 HIPK2 25348397 N/A physical interaction ComPPI
SIAH1 HERPUD1 25348397 N/A physical interaction ComPPI
SIAH1 CTNNB1 25348397 N/A physical interaction ComPPI
SIAH1 SEPTIN4 21185211 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SIAH1 ATXN7 21078624 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
SIAH1 SNCA 25348397 N/A physical interaction ComPPI
SIAH1 PSMC5 25348397 N/A physical interaction ComPPI
SIAH1 TERF2 21057505 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SIAH1 FLT3 25348397 N/A physical interaction ComPPI
SIAH1 PARD3 25348397 N/A physical interaction ComPPI
SIAH1 ELL2 25348397 N/A physical interaction ComPPI
SIAH1 USP19 25348397 N/A physical interaction ComPPI
SIAH1 HTT 25348397 N/A physical interaction ComPPI
SIAH1 KLF10 25348397 N/A physical interaction ComPPI
SIAH1 HIPK1 25348397 N/A physical interaction ComPPI
SIAH1 RNF2 25348397 N/A physical interaction ComPPI
SIAH1 ATN1 14525934 16713569 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SIAH1 PUF60 21516116 21988832 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 TNK2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 GRM5 23152621 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SIAH1 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIAH1 MYD88 21988832 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
SIAH1 TXN 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
SIAH1 TFDP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 STAT3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 NUMBL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 RAPH1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 MAPRE3 25348397 N/A physical interaction ComPPI
SIAH1 AQP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 TRIM23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 BCL6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 CAPG 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 PHC1 25348397 N/A physical interaction ComPPI
SIAH1 KIFC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 MX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 PFKM 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 RPL27A 25348397 N/A physical interaction ComPPI
SIAH1 MAPK12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 NELFA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 ZNF148 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 CDC23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 SYT7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 MAPKBP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 RAD54L2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 PRPF31 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 TOLLIP 25348397 N/A physical interaction ComPPI
SIAH1 ZCCHC10 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 NTAQ1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 CCDC198 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 KIAA1217 25348397 N/A physical interaction ComPPI
SIAH1 AASDHPPT 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 ZMAT3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 NOL6 25348397 N/A physical interaction ComPPI
SIAH1 OTUB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 ZFYVE21 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 KIAA0319L 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 ARMC9 25348397 N/A physical interaction ComPPI
SIAH1 IQCN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 ZBP1 25348397 N/A physical interaction ComPPI
SIAH1 GDPD5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 TRIM7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 SPATC1L 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 EXOC3-AS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 UPP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 MAP3K5 25348397 N/A physical interaction ComPPI
SIAH1 DLD 25348397 N/A physical interaction ComPPI
SIAH1 JSRP1 25348397 N/A physical interaction ComPPI
SIAH1 LATS2 25348397 N/A physical interaction ComPPI
SIAH1 EXOC3L2 25348397 N/A physical interaction ComPPI
SIAH1 TP73 24234451 25348397 25774835 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIAH1 SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
RAD51AP1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDC34 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PYGB SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KCNJ10 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KIF1B SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EEF1D SIAH1 21633900 21988832 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
ZCCHC13 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FZD9 SIAH1 25348397 N/A physical interaction ComPPI
TMEM43 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DNALI1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RPS19BP1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
INHA SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DDX41 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF671 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DNAJC15 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPATA4 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LACTB2 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MTIF3 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAB21L1 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIAH1 SIAH1 12810624 14525934 21988832 22493164 24234451 25416956 9582267 physical association two hybrid,experimental interaction detection,two hybrid array,two hybrid HPRD,IntAct
TUBA3C SIAH1 11146551 14525934 N/A two hybrid HPRD
SIAH1 CTNNB1 11389840 20181957 24882689 27898060 inhibition N/A OmniPath
SIAH1 NUMB 11752454 21988832 27898060 inhibition N/A OmniPath
SIAH1 SNCAIP 14506261 15064394 16174773 27898060 inhibition N/A OmniPath
ATR SIAH1 18536714 27898060 N/A N/A OmniPath
ATM SIAH1 18536714 19788416 27898060 inhibition N/A OmniPath
MYD88 SIAH1 21988832 27898060 N/A N/A OmniPath
TP53 SIAH1 15326481 27898060 stimulant N/A OmniPath
SIAH1 NOTCH1 20940030 27898060 stimulant N/A OmniPath
SIAH1 HIPK2 18536714 19043406 19250734 19788416 23503458 27898060 inhibition N/A OmniPath

Visualization










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