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GENE：SLC25A6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC25A6
FullNmae solute carrier family 25 member 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10992
EnsembleID ENSG00000169100
Uniprot P12236

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC25A6 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC25A6 GO:0005471,GO:0005515,GO:0005634,GO:0005739,GO:0005739,GO:0005743,GO:0005744,GO:0006915,GO:0016020,GO:0140021,GO:1901029,GO:1990544

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC25A6 hsa:293 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa04217 Necroptosis - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa04218 Cellular senescence - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05010 Alzheimer disease - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05012 Parkinson disease - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05016 Huntington disease - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05020 Prion disease - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05164 Influenza A - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
SLC25A6 hsa:293 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMAD2 SLC25A6 18729074 23180781 physical association tandem affinity purification InnateDB
ADRB2 SLC25A6 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB
AP2B1 SLC25A6 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 TRIM23 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 KRT31 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 TRAF1 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 TRIP6 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 MID2 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 MTUS2 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 LZTS2 23180781 25416956 physical association two hybrid InnateDB
SLC25A6 TEKT4 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SLC25A6 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC SLC25A6 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SLC25A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004505E4 SLC25A6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 SLC25A6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000029D9F1 SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000308E4D SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000192A75 SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000759B6A SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001A6D0C SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000065FDF SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004C689A SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C SLC25A6 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000023BE29 SLC25A6 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TEKT4 SLC25A6 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CHCHD2 SLC25A6 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MAD2L2 SLC25A6 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
KRTAP4-12 SLC25A6 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CIAO2B SLC25A6 25348397 N/A physical interaction ComPPI
VAMP2 SLC25A6 25348397 N/A physical interaction ComPPI
BAG3 SLC25A6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LZTS2 SLC25A6 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VIM SLC25A6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TOMM22 SLC25A6 25348397 N/A physical interaction ComPPI
LMNA SLC25A6 25348397 N/A physical interaction ComPPI
SLC25A6 KRT31 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 FGFR3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC25A6 PLSCR1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC25A6 KARS1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 PRSS23 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 CHGB 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC25A6 STRN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC25A6 MGMT 25348397 N/A physical interaction ComPPI
SLC25A6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 SIRT4 17715127 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 MRPL58 25348397 N/A physical interaction ComPPI
SLC25A6 HDAC5 25348397 N/A physical interaction ComPPI
SLC25A6 NDRG1 17220478 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 CUL3 25348397 N/A physical interaction ComPPI
SLC25A6 CUL4A 25348397 N/A physical interaction ComPPI
SLC25A6 CUL1 25348397 N/A physical interaction ComPPI
SLC25A6 COPS5 25348397 N/A physical interaction ComPPI
SLC25A6 CAND1 25348397 N/A physical interaction ComPPI
SLC25A6 SMAD2 18729074 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
SLC25A6 INPPL1 25348397 N/A physical interaction ComPPI
SLC25A6 TIMM13 25348397 N/A physical interaction ComPPI
SLC25A6 TIMM10 25348397 N/A physical interaction ComPPI
SLC25A6 TIMM50 25348397 N/A physical interaction ComPPI
SLC25A6 TIMM9 25348397 N/A physical interaction ComPPI
SLC25A6 RPL10L 25348397 N/A physical interaction ComPPI
SLC25A6 RPL7A 25348397 N/A physical interaction ComPPI
SLC25A6 RPL10 25348397 N/A physical interaction ComPPI
SLC25A6 RPL10A 25348397 N/A physical interaction ComPPI
SLC25A6 NNT 25348397 N/A physical interaction ComPPI
SLC25A6 NDUFB8 25348397 N/A physical interaction ComPPI
SLC25A6 UQCRC1 25348397 N/A physical interaction ComPPI
SLC25A6 NDUFV3 25348397 N/A physical interaction ComPPI
SLC25A6 YWHAE 25348397 N/A physical interaction ComPPI
SLC25A6 GRB2 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 UBL4A 25348397 N/A physical interaction ComPPI
SLC25A6 CLN3 25348397 N/A physical interaction ComPPI
SLC25A6 CLN5 25348397 N/A physical interaction ComPPI
SLC25A6 ADRB2 25348397 N/A physical interaction ComPPI
SLC25A6 FBXO6 25348397 N/A physical interaction ComPPI
SLC25A6 HECW2 25348397 N/A physical interaction ComPPI
SLC25A6 ASB8 25348397 N/A physical interaction ComPPI
SLC25A6 ASB14 25348397 N/A physical interaction ComPPI
SLC25A6 SMURF2 25348397 N/A physical interaction ComPPI
SLC25A6 ZBTB1 25348397 N/A physical interaction ComPPI
SLC25A6 AP2M1 25348397 N/A physical interaction ComPPI
SLC25A6 HUWE1 25348397 N/A physical interaction ComPPI
SLC25A6 AP2B1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 TRIM23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 TRAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 TRIP6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 MID2 25348397 N/A physical interaction ComPPI
SLC25A6 MTUS2 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A6 CCDC8 25348397 N/A physical interaction ComPPI
SLC25A6 FAM187B 25348397 N/A physical interaction ComPPI
SLC25A6 LCOR 25348397 N/A physical interaction ComPPI
SLC25A6 VSIG4 25348397 N/A physical interaction ComPPI
SLC25A6 ISLR 25348397 N/A physical interaction ComPPI
SLC25A6 NTRK1 25348397 N/A physical interaction ComPPI
SLC25A6 ATP6V0D1 25348397 N/A physical interaction ComPPI
SLC25A6 PMM2 25348397 N/A physical interaction ComPPI
SLC25A6 SLC25A20 25348397 N/A physical interaction ComPPI
SLC25A6 SLC25A24 25348397 N/A physical interaction ComPPI
SLC25A6 TOMM20 25348397 N/A physical interaction ComPPI
SLC25A6 CHEK2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SLC25A6 NDUFA13 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 AHSA1 25348397 N/A physical interaction ComPPI
SLC25A6 SCAF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 POLR3E 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 GAN 25348397 N/A physical interaction ComPPI
SLC25A6 SKI 25348397 N/A physical interaction ComPPI
SLC25A6 MCM2 25348397 N/A physical interaction ComPPI
SLC25A6 NF2 25348397 N/A physical interaction ComPPI
SLC25A6 ERBB3 25348397 N/A physical interaction ComPPI
SLC25A6 ESRRB 25348397 N/A physical interaction ComPPI
SLC25A6 CDC37 25348397 N/A physical interaction ComPPI
SLC25A6 COQ9 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 NDUFA4 25348397 N/A physical interaction ComPPI
SLC25A6 CHCHD10 25348397 N/A physical interaction ComPPI
SLC25A6 NMES1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A6 DGLUCY 25348397 N/A physical interaction ComPPI
SLC25A6 LRP1 25348397 N/A physical interaction ComPPI
SLC25A6 GLMP 25348397 N/A physical interaction ComPPI
SLC25A6 DKK3 25348397 N/A physical interaction ComPPI
SLC25A6 CHRM4 25348397 N/A physical interaction ComPPI
SLC25A6 SPACA1 25348397 N/A physical interaction ComPPI
SLC25A6 CD79B 25348397 N/A physical interaction ComPPI
SLC25A6 ERGIC3 25348397 N/A physical interaction ComPPI
SLC25A6 PDCD1 25348397 N/A physical interaction ComPPI
SLC25A6 FAM131B 25348397 N/A physical interaction ComPPI
SLC25A6 THBS4 25348397 N/A physical interaction ComPPI
SLC25A6 THBS3 25348397 N/A physical interaction ComPPI
SLC25A6 TMCO3 25348397 N/A physical interaction ComPPI
SLC25A6 CLEC2D 25348397 N/A physical interaction ComPPI
SLC25A6 PMEL 25348397 N/A physical interaction ComPPI
SLC25A6 GAA 25348397 N/A physical interaction ComPPI
SLC25A6 CNDP1 25348397 N/A physical interaction ComPPI
SLC25A6 CYLD 25348397 N/A physical interaction ComPPI
SLC25A6 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SLC25A6 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SLC25A6 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SLC25A6 VDAC1 21370995 24234451 25348397 29128334 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
SLC25A6 TRIM25 25348397 N/A physical interaction ComPPI
SLC25A6 ATXN3 25348397 N/A physical interaction ComPPI
SLC25A6 KEAP1 25348397 N/A physical interaction ComPPI
SLC25A6 IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 MAP3K3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 RELA 25348397 N/A tandem affinity purification ComPPI
SLC25A6 TNFRSF1A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 TNFRSF1B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 TRADD 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SLC25A6 CHD3 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 RACK1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 CUTC 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 TNFRSF10C 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 TMEM62 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SLC25A6 A2M 17174955 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
SLC25A6 AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 YWHAH 17979178 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SLC25A6 MAX 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SLC25A6 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
SLC25A6 LRRK2 21370995 24234451 24725412 25348397 association,physical association anti tag coimmunoprecipitation,tandem affinity purification ComPPI,IntAct
SLC25A6 SLC25A5 23260140 24234451 25348397 association blue native page ComPPI,IntAct
SLC25A6 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 ESR1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
SLC25A6 NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
SLC25A6 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SLC25A6 TERF2IP 21044950 24234451 25348397 physical association pull down ComPPI,IntAct
SLC25A6 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
SLC25A6 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 TUBA1A 24234451 25348397 29568061 association pull down ComPPI,IntAct
SLC25A6 COQ2 24234451 25348397 27499296 29128334 association anti tag coimmunoprecipitation,cross-linking study ComPPI,IntAct
SLC25A6 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 NDUFAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 HOGA1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 LACTB 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 LYRM1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 CISD3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 SDHAF3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 OPA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 COQ10A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 FMC1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 ADCK1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A6 NDUFS3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MKI67 SLC25A6 24234451 26949251 association anti tag coimmunoprecipitation IntAct
METTL14 SLC25A6 24234451 29507755 association anti tag coimmunoprecipitation IntAct
DICER1 SLC25A6 21858095 24234451 association anti tag coimmunoprecipitation IntAct
RRBP1 SLC25A6 24234451 30021884 physical association cross-linking study IntAct
TPT1 SLC25A6 24234451 27607350 association anti bait coimmunoprecipitation IntAct

Visualization










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