GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
SLFN12 |
| FullNmae |
schlafen family member 12 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:25500 |
| EnsembleID |
ENSG00000172123 |
| Uniprot |
Q8IYM2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| SLFN12 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| SLFN12 |
apoptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| SLFN12 |
GO:0004540,GO:0004540,GO:0005515,GO:0005634,GO:0005829,GO:0016075,GO:0016075,GO:0043022,GO:0097190,GO:0140102 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| SMARCA4 |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| PRDM14 |
SLFN12 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS000003ABC4 |
SLFN12 |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000000EF0B |
SLFN12 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00005D986D |
SLFN12 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000018CD09 |
SLFN12 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002E728C |
SLFN12 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00005F9738 |
SLFN12 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00005FDE70 |
SLFN12 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000004BACE |
SLFN12 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| PDLIM7 |
SLFN12 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SUV39H1 |
SLFN12 |
23455924
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| JMJD6 |
SLFN12 |
23455924
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
Visualization