Gene Information gene info

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GENE：PRKCZ

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRKCZ
FullNmae protein kinase C zeta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9412
EnsembleID ENSG00000067606
Uniprot Q05513

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRKCZ pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRKCZ necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRKCZ GO:0000226,GO:0001725,GO:0001954,GO:0004672,GO:0004674,GO:0004674,GO:0004697,GO:0004697,GO:0004698,GO:0005515,GO:0005524,GO:0005635,GO:0005737,GO:0005768,GO:0005815,GO:0005829,GO:0005829,GO:0005886,GO:0005911,GO:0005923,GO:0006468,GO:0006954,GO:0007165,GO:0007166,GO:0007616,GO:0008284,GO:0014069,GO:0015459,GO:0016020,GO:0016324,GO:0016363,GO:0016477,GO:0018105,GO:0018105,GO:0019901,GO:0030010,GO:0030054,GO:0031252,GO:0031333,GO:0031982,GO:0032733,GO:0032736,GO:0032753,GO:0032754,GO:0032869,GO:0035556,GO:0035748,GO:0043066,GO:0043203,GO:0043274,GO:0043560,GO:0044877,GO:0045179,GO:0045197,GO:0045630,GO:0046627,GO:0046628,GO:0046872,GO:0047496,GO:0048471,GO:0050732,GO:0051092,GO:0051222,GO:0051899,GO:0060081,GO:0060291,GO:0070062,GO:0070160,GO:0070374,GO:0070528,GO:0071889,GO:0072659,GO:0098685,GO:0098696,GO:0098978,GO:0106310,GO:0120157,GO:1990138,GO:2000463,GO:2000553

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRKCZ hsa:5590 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04144 Endocytosis - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04360 Axon guidance - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04530 Tight junction - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04611 Platelet activation - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04930 Type II diabetes mellitus - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04931 Insulin resistance - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)
PRKCZ hsa:5590 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRKCZ BAX 10873802 10934475 10954424 14766748 15642728 17525161 20505164 26192618 interaction type N/A ACSN
SQSTM1 PRKCZ 11755531 12887891 15870274 19850933 23180781 9566925 physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,gst pull down InnateDB
RIPK1 PRKCZ 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PRKCZ 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCZ IRAK1 11937546 23180781 physical association anti tag coimmunoprecipitation InnateDB
AJUBA PRKCZ 15870274 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
TLR2 PRKCZ 16925784 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 PRKCZ 10747026 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSNK2B PRKCZ 10764587 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
CSNK2A1 PRKCZ 10764587 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
NFKBIA PRKCZ 10764587 12893839 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
PRKCZ PRKCZ 11078718 15665819 23180781 phosphorylation reaction mass spectrometry studies of complexes,in-gel kinase assay,protein kinase assay InnateDB
PRKCSH PRKCZ 15707389 23180781 physical association two hybrid,pull down InnateDB
ADAP1 PRKCZ 12893243 23180781 phosphorylation reaction,physical association pull down,protein kinase assay InnateDB
HABP4 PRKCZ 14699138 23180781 phosphorylation reaction protein kinase assay InnateDB
PARD6B PRKCZ 11260256 23180781 physical association two hybrid,pull down InnateDB
PARD6A PRKCZ 10873802 11260256 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
PRKCZ CDC42 10733591 10873802 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
RAC1 PRKCZ 10873802 23180781 physical association anti tag coimmunoprecipitation InnateDB
PDPK1 PRKCZ 10764742 23180781 physical association two hybrid,pull down InnateDB
PPP1R14A PRKCZ 15003508 23180781 phosphorylation reaction,physical association pull down,protein kinase assay InnateDB
WWC1 PRKCZ 15081397 23180781 phosphorylation reaction,physical association pull down,protein kinase assay InnateDB
PAWR PRKCZ 11755531 16209943 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCZ AKT3 12162751 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
C1QBP PRKCZ 10831594 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
FADD PRKCZ 11739185 23180781 physical association anti tag coimmunoprecipitation InnateDB
AKT1 PRKCZ 11585925 18353613 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCZ AKT1 11585925 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCZ KRT10 11585925 23180781 physical association anti tag coimmunoprecipitation InnateDB
KRT10 PRKCZ 11585925 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAP2K5 PRKCZ 11158308 23180781 physical association anti tag coimmunoprecipitation InnateDB
RELA PRKCZ 11684013 23180781 physical association anti tag coimmunoprecipitation InnateDB
RPS6KB1 PRKCZ 16931574 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCF1 PRKCZ 11145703 23180781 phosphorylation reaction protein kinase assay InnateDB
FAS PRKCZ 15993755 23180781 physical association anti tag coimmunoprecipitation InnateDB
F11R PRKCZ 17057644 23180781 physical association pull down InnateDB
PRKCQ PRKCZ 17588663 23180781 physical association two hybrid InnateDB
AKT2 PRKCZ 18353613 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCZ CASP9 16287866 23180781 phosphorylation reaction pull down,protein kinase assay InnateDB
SLC22A8 PRKCZ 19028678 23180781 physical association two hybrid InnateDB
BAX PRKCZ 17525161 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
PIK3CG PRKCZ 16527821 23180781 physical association anti tag coimmunoprecipitation InnateDB
PIK3R1 PRKCZ 17408603 23180781 physical association anti tag coimmunoprecipitation InnateDB
NR1H4 PRKCZ 18668687 23180781 physical association protein kinase assay InnateDB
BLVRA PRKCZ 17639074 23180781 phosphorylation reaction anti tag coimmunoprecipitation,protein kinase assay InnateDB
SP1 PRKCZ 16943418 23180781 physical association anti tag coimmunoprecipitation InnateDB
AGER PRKCZ 21829704 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
YWHAB PRKCZ 10620507 21900206 23331499 stimulation N/A SignaLink
YWHAZ PRKCZ 10620507 23331499 stimulation N/A SignaLink
PRKCZ PARD3 17353362 23109003 24152735 chemical activation reaction N/A SignaLink
CDC42 PRKCZ 17353362 23109003 chemical activation reaction N/A SignaLink
PRKCZ MAPK1 11035106 12900386 12942541 23109003 chemical activation reaction N/A SignaLink
PRKCZ MAPK3 11035106 12900386 12942541 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
FADD PRKCZ 20005715 interaction type N/A PSP
FRS2 PRKCZ 20005715 interaction type N/A PSP
GRB14 PRKCZ 20005715 interaction type N/A PSP
IRS1 PRKCZ 20005715 interaction type N/A PSP
IRS4 PRKCZ 20005715 interaction type N/A PSP
PARD3 PRKCZ 20005715 interaction type N/A PSP,SignaLink
SQSTM1 PRKCZ 10356400 12813044 18988627 20005715 9566925 interaction type N/A PSP,SignaLink
YWHAB PRKCZ 20005715 interaction type N/A PSP,SignaLink
YWHAG PRKCZ 20005715 interaction type N/A PSP
YWHAH PRKCZ 20005715 interaction type N/A PSP
YWHAQ PRKCZ 20005715 interaction type N/A PSP
YWHAZ PRKCZ 20005715 interaction type N/A PSP
GRB14 PRKCZ 12242277 18988627 20005715 N/A N/A SignaLink
FRS2 PRKCZ 10383403 18988627 20005715 N/A N/A SignaLink
IRS4 PRKCZ 12774026 18988627 20005715 N/A N/A SignaLink
YWHAQ PRKCZ 10620507 20005715 21071413 N/A N/A SignaLink
YWHAZ PRKCZ 20005715 N/A N/A SignaLink
IRS1 PRKCZ 20005715 N/A N/A SignaLink
FADD PRKCZ 11739185 18988627 20005715 N/A N/A SignaLink
YWHAG PRKCZ 10620507 20005715 21071413 N/A N/A SignaLink
YWHAH PRKCZ 10620507 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 PRKCZ 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PRKCZ 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PRKCZ 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 PRKCZ 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PRKCZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171525 PRKCZ 25416803 28218902 mrna cleavage,inhibition array technology,experimental interaction detection,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000C85B2 PRKCZ 25416803 27911275 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
PDPK1 PRKCZ 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCZ PTEN 22135298 phosphorylation N/A PhosphoSite
PRKCZ NCOA3 22135298 phosphorylation N/A PhosphoSite
PRKCZ OCLN 22135298 phosphorylation N/A PhosphoSite
PRKCZ MARK2 22135298 phosphorylation N/A PhosphoSite
PRKCZ RND3 22135298 phosphorylation N/A PhosphoSite
PRKCZ PHGDH 22135298 phosphorylation N/A PhosphoSite
PRKCZ GSK3B 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCZ AQP9 22135298 phosphorylation N/A PhosphoSite
PRKCZ MYH10 22135298 phosphorylation N/A PhosphoSite
PRKCZ RPS6KB2 22135298 phosphorylation N/A PhosphoSite
PRKCZ SP1 22135298 phosphorylation N/A PhosphoSite
PRKCZ BAX 22135298 phosphorylation N/A PhosphoSite
PRKCZ SMARCD3 22135298 phosphorylation N/A PhosphoSite
PRKCZ STK11 22135298 phosphorylation N/A PhosphoSite
PRKCZ MARK3 22135298 phosphorylation N/A PhosphoSite
PRKCZ PPP1R14A 22135298 phosphorylation N/A PhosphoSite
PRKCZ IRS1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCZ PIAS4 22135298 phosphorylation N/A PhosphoSite
PRKCZ CTNNB1 22135298 phosphorylation N/A PhosphoSite
PRKCZ ADD2 22135298 phosphorylation N/A PhosphoSite
PRKCZ ADD1 22135298 phosphorylation N/A PhosphoSite
PRKCZ CASP9 22135298 phosphorylation N/A PhosphoSite
PRKCZ NR0B2 22135298 phosphorylation N/A PhosphoSite
PRKCZ YAP1 22135298 phosphorylation N/A PhosphoSite
PRKCZ HABP4 22135298 phosphorylation N/A PhosphoSite
PRKCZ IKBKB 22135298 phosphorylation N/A PhosphoSite
PRKCZ WWC1 22135298 phosphorylation N/A PhosphoSite
PRKCZ NREP 22135298 phosphorylation N/A PhosphoSite
PRKCZ GEM 22135298 phosphorylation N/A PhosphoSite
PRKCZ TRAF2 22135298 phosphorylation N/A PhosphoSite
PRKCZ NCF1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCZ RELA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
IRAK1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ IRAK1 25361965 interaction type N/A PTMCode2
HRAS PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ HRAS 25361965 interaction type N/A PTMCode2
PARD6B PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PARD6B 25361965 interaction type N/A PTMCode2
GRB14 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ GRB14 25361965 interaction type N/A PTMCode2
PARD6A PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PARD6A 25361965 interaction type N/A PTMCode2
GSK3B PRKCZ 25361965 interaction type N/A PTMCode2
RAF1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ RAF1 25361965 interaction type N/A PTMCode2
TIAM1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ TIAM1 25361965 interaction type N/A PTMCode2
MAPK1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ MAPK1 25361965 interaction type N/A PTMCode2
PRKCI PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PRKCI 25361965 interaction type N/A PTMCode2
ECT2 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ ECT2 25361965 interaction type N/A PTMCode2
JAK1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ JAK1 25361965 interaction type N/A PTMCode2
PAWR PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PAWR 25361965 interaction type N/A PTMCode2
AKT3 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ AKT3 25361965 interaction type N/A PTMCode2
STAT6 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ STAT6 25361965 interaction type N/A PTMCode2
PARD3 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PARD3 25361965 interaction type N/A PTMCode2
SRC PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ SRC 25361965 interaction type N/A PTMCode2
NCL PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ NCL 25361965 interaction type N/A PTMCode2
FEZ1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ FEZ1 25361965 interaction type N/A PTMCode2
YWHAB PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ YWHAB 25361965 interaction type N/A PTMCode2
GLRX3 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ GLRX3 25361965 interaction type N/A PTMCode2
IRS1 PRKCZ 25361965 interaction type N/A PTMCode2
AKT1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ AKT1 25361965 interaction type N/A PTMCode2
PRKCZ FEZ2 25361965 interaction type N/A PTMCode2
FEZ2 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ NFATC2 25361965 interaction type N/A PTMCode2
NFATC2 PRKCZ 25361965 interaction type N/A PTMCode2
RELA PRKCZ 25361965 interaction type N/A PTMCode2
NCF1 PRKCZ 25361965 interaction type N/A PTMCode2
TRAF6 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ TRAF6 25361965 interaction type N/A PTMCode2
FADD PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ FADD 25361965 interaction type N/A PTMCode2
NUMB PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ NUMB 25361965 interaction type N/A PTMCode2
PEBP1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PEBP1 25361965 interaction type N/A PTMCode2
PRKCZ PDPK1 25361965 interaction type N/A PTMCode2
CDC42 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ CDC42 25361965 interaction type N/A PTMCode2
F11R PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ F11R 25361965 interaction type N/A PTMCode2
IRS4 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ IRS4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DYNLL1 PRKCZ 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC42 PRKCZ 10733591 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GLRX3 PRKCZ 10636891 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NPM1 PRKCZ 25348397 N/A physical interaction ComPPI
CFL1 PRKCZ 25348397 N/A physical interaction ComPPI
TRAF6 PRKCZ 10747026 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
YWHAG PRKCZ 25348397 N/A physical interaction ComPPI
CASP9 PRKCZ 14525934 16287866 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSP90AB1 PRKCZ 22939624 24234451 25348397 physical association anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping ComPPI,IntAct
APPL1 PRKCZ 25348397 N/A physical interaction ComPPI
CD44 PRKCZ 25348397 N/A physical interaction ComPPI
MAPK1 PRKCZ 14525934 15721486 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HRAS PRKCZ 14525934 15721486 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BTK PRKCZ 11788586 14525934 25348397 7522330 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCQ PRKCZ 17588663 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,protein kinase assay ComPPI,IntAct
TIAM1 PRKCZ 25348397 N/A physical interaction ComPPI
SP1 PRKCZ 25348397 N/A physical interaction ComPPI
PRKCA PRKCZ 10339425 12162751 14525934 25348397 8856079 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SRC PRKCZ 10527887 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCD PRKCZ 11381116 12162751 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CASP3 PRKCZ 11016947 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK3 PRKCZ 14525934 15721486 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NCOA3 PRKCZ 25348397 N/A physical interaction ComPPI
FRS2 PRKCZ 10383403 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
RHOA PRKCZ 14525934 15210811 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FEZ1 PRKCZ 14525934 25348397 9971736 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
GSK3B PRKCZ 11481324 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
YWHAB PRKCZ 10620507 14525934 21900206 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
YWHAZ PRKCZ 25348397 N/A physical interaction ComPPI
IRS4 PRKCZ 12774026 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HSP90AA1 PRKCZ 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
JAK1 PRKCZ 14525934 15526032 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CKAP4 PRKCZ 25348397 N/A physical interaction ComPPI
GRB14 PRKCZ 12242277 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CASP6 PRKCZ 11016947 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NUMB PRKCZ 14525934 17203073 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD
PDPK1 PRKCZ 10357815 10764742 11222751 11781095 14500673 14525934 25348397 9748166 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PRG2 PRKCZ 10357815 11222751 14500673 14525934 25348397 9748166 N/A experimental interaction detection,in vitro ComPPI,HPRD
MSH6 PRKCZ 25348397 N/A physical interaction ComPPI
CASP7 PRKCZ 11016947 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CASP8 PRKCZ 11016947 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
IKBKB PRKCZ 10022904 10195894 10779355 14525934 25348397 9689078 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAP2K1 PRKCZ 11535599 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PEBP1 PRKCZ 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
F11R PRKCZ 17057644 24234451 25241761 25348397 physical association pull down,physical interaction,proximity ligation assay ComPPI,IntAct
AGER PRKCZ 21829704 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPL PRKCZ 25348397 N/A physical interaction ComPPI
C1QBP PRKCZ 10831594 14525934 24234451 25348397 25852190 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCZ NCF1 24234451 25348397 27040869 colocalization,physical association anti bait coimmunoprecipitation,pull down,physical interaction,fluorescence microscopy,in vitro ComPPI,IntAct
PRKCZ IRAK1 11937546 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ NFATC2 12021260 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ SQSTM1 10356400 12813044 14525934 24234451 25348397 25852190 9566925 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PRKCZ FADD 11739185 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ MAP2K5 25348397 N/A physical interaction,in vivo ComPPI
PRKCZ DAPK3 12242277 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKCZ PARD6A 11260256 12813044 14525934 14676191 16189514 17057644 17335965 17350623 24234451 25348397 25852190 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,imaging technique,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PRKCZ AKT3 12162751 14525934 24234451 25241761 25348397 9305920 9512493 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
PRKCZ ADCY5 14525934 25348397 8206971 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ PAWR 14525934 25348397 8797824 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKCZ FEZ2 14525934 14697253 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ ADAP1 12893243 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKCZ AFAP1 12134071 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ WWC1 14525934 15081397 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PRKCZ PARD6G 11260256 14525934 14676191 17057644 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PRKCZ PDLIM7 14525934 25348397 8940095 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ HABP4 14525934 14699138 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCZ PPP1R14A 14525934 15003508 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKCZ PARD6B 11260256 14525934 14676191 24234451 25348397 25852190 27107012 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
PRKCZ PPP3CA 12021260 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKCZ CSNK2B 10764587 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKCZ MBP 10383403 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKCZ CHAT 14525934 15381704 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ GRM5 24234451 25241761 25348397 physical association physical interaction,in vitro,proximity ligation assay ComPPI,IntAct
PRKCZ IL4R 14525934 15526032 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCZ STAT6 14525934 15526032 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKCZ GSK3A 11481324 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCZ FYN 14525934 25348397 8621384 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ SLC39A1 10477520 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKCZ IRS1 11063744 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCZ PSEN1 14525934 14576165 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCZ KRT10 11585925 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ RELA 11684013 12881425 14525934 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCZ AKT1 10085094 11723139 14525934 14560023 18650932 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCZ RAF1 10620507 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCZ ECT2 25348397 N/A physical interaction ComPPI
PRKCZ RPS6KB1 25348397 N/A physical interaction ComPPI
PRKCZ NCL 14525934 25348397 9388266 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PRKCZ YWHAH 25348397 N/A physical interaction ComPPI
PRKCZ PARD3 25348397 N/A physical interaction ComPPI
PRKCZ HSP90AA2P 25348397 N/A physical interaction ComPPI
PRKCZ MSH2 25348397 N/A physical interaction ComPPI
PRKCZ TLR4 25348397 N/A physical interaction ComPPI
PRKCZ TLR9 25348397 N/A physical interaction ComPPI
PRKCZ STUB1 25348397 N/A physical interaction ComPPI
PRKCZ ZNF71 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKCZ UTP14A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKCZ NMT2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKCZ DENND5A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKCZ CCDC115 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKCZ PIAS4 25348397 N/A physical interaction ComPPI
PRKCZ TRIM41 25348397 N/A physical interaction ComPPI
PRKCZ ESR1 25348397 N/A physical interaction ComPPI
PRKCZ VHL 10491320 17101696 17350623 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,physical interaction,imaging technique ComPPI,IntAct,OmniPath
PRKCZ AJUBA 25348397 N/A physical interaction ComPPI
PRKCZ LRRK2 25348397 N/A physical interaction ComPPI
PRKCZ NCF1B 25348397 N/A physical interaction ComPPI
PRKCZ H1-1 25348397 N/A physical interaction ComPPI
PRKCZ MARCKS 25348397 N/A physical interaction ComPPI
PRKCZ H1-5 25348397 N/A physical interaction ComPPI
PRKCZ AKT2 25348397 N/A physical interaction ComPPI
PRKCZ MAPK7 25348397 N/A physical interaction ComPPI
PRKCZ EGFR 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PRKCZ ABL1 25348397 N/A physical interaction ComPPI
PRKCZ LLGL1 24234451 24366813 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKCZ LLGL2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKCZ NIPSNAP2 25348397 N/A physical interaction ComPPI
PRKCZ CDC42BPB 25348397 N/A physical interaction ComPPI
PRKCZ GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKCZ RICTOR 24234451 24375676 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
YWHAQ PRKCZ 25348397 N/A physical interaction ComPPI
PRKCI PRKCZ 11260256 24234451 24375676 25348397 25852190 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL10 PRKCZ 24234451 25011391 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy,proximity ligation assay ComPPI,IntAct,OmniPath
BLVRA PRKCZ 25348397 N/A physical interaction ComPPI
PRKCZ PRKCZ 14525934 9748166 N/A experimental interaction detection HPRD
PRKCZ NUMB 17203073 24234451 phosphorylation reaction protein kinase assay IntAct
PRKCA PRKCZ 10339425 11222751 12162751 27898060 8856079 N/A N/A OmniPath
PRKCZ PRKCA 10339425 12162751 18691976 20068231 27898060 8856079 N/A N/A OmniPath
PRKCZ NUMB 17203073 18767875 27898060 N/A N/A OmniPath
PRKCZ PRKCSH 15707389 27898060 N/A N/A OmniPath
PRKCZ NOS3 24379783 27898060 inhibition N/A OmniPath
PRKCZ PRKCD 11381116 12162751 15302935 18452278 18669648 18691976 20058876 20068231 27898060 N/A N/A OmniPath
PRKCZ TRAF2 19336568 27898060 N/A N/A OmniPath
PRKCZ FADD 11739185 27898060 inhibition,stimulant N/A OmniPath
AJUBA PRKCZ 15870274 27898060 N/A N/A OmniPath
PRKCZ STK11 17635921 18250273 19414597 20724523 27898060 stimulant N/A OmniPath
CASP9 PRKCZ 16287866 27898060 N/A N/A OmniPath
PRKCZ CASP9 15703181 16287866 27898060 inhibition N/A OmniPath
PRKCZ NCOA3 18313384 27898060 N/A N/A OmniPath
TRAF6 PRKCZ 10747026 27898060 N/A N/A OmniPath
PDPK1 PRKCZ 10075713 10357815 10764742 11141077 11222751 11781095 12781924 12887331 14500673 15314172 16051884 16129678 16943418 17335005 18691976 20332120 21946537 27898060 9748166 9768361 stimulant N/A OmniPath
PRKCZ PDPK1 10357815 10764742 11141077 11222751 11781095 14500673 27898060 9748166 N/A N/A OmniPath
PRKCZ PEBP1 12551925 14654844 20068231 20166139 27898060 stimulant N/A OmniPath
PRKCZ BLVRA 17639074 27898060 N/A N/A OmniPath
AKT1 PRKCZ 10085094 11585925 11723139 14560023 18353613 18650932 27898060 N/A N/A OmniPath
PRKCZ AKT1 10085094 11585925 11723139 14560023 18353613 18650932 27898060 inhibition N/A OmniPath
PRKCZ IRS1 11063744 15069075 15516986 16020478 16129678 17360977 27898060 inhibition,stimulant N/A OmniPath
PRKCZ MYH10 16611744 27898060 inhibition N/A OmniPath
YWHAZ PRKCZ 10620507 12893243 27898060 stimulant N/A OmniPath
TLR2 PRKCZ 16925784 27898060 N/A N/A OmniPath
PRKCZ TLR2 16925784 27898060 N/A N/A OmniPath
PRKCZ PRKCQ 17588663 27898060 N/A N/A OmniPath
PRKCZ RAC1 10873802 27898060 N/A N/A OmniPath
PRKCZ NFKBIA 10764587 12893839 27898060 inhibition N/A OmniPath
PRKCZ PIK3R1 17408603 27898060 N/A N/A OmniPath
PRKCZ SP1 16943418 18258854 19464346 20953893 27898060 stimulant N/A OmniPath
PRKCZ RELA 10521409 11684013 12767944 12881425 15210811 15485852 15849198 17183360 21131967 21515635 27898060 stimulant N/A OmniPath
PRKCZ AKT3 12162751 25241761 27898060 9305920 9512493 inhibition,stimulant N/A OmniPath
AKT3 PRKCZ 12162751 25241761 27898060 9305920 9512493 N/A N/A OmniPath
PRKCZ MARK2 15084291 27898060 inhibition N/A OmniPath
CSNK2A1 PRKCZ 10764587 27898060 N/A N/A OmniPath
PRKCZ CSNK2A1 10764587 27898060 N/A N/A OmniPath
PRKCZ BAX 14766748 15642728 16679323 17525161 17911107 27898060 inhibition N/A OmniPath
PRKCZ MAP2K5 11158308 27898060 N/A N/A OmniPath
PRKCZ PSEN1 14576165 27898060 stimulant N/A OmniPath
CDC42 PRKCZ 10733591 10873802 27898060 stimulant N/A OmniPath
CSNK2B PRKCZ 10764587 27898060 N/A N/A OmniPath
PRKCZ CSNK2B 10764587 27898060 N/A N/A OmniPath
PRKCZ AKT2 18353613 27898060 N/A N/A OmniPath
SQSTM1 PRKCZ 10356400 10747026 11755531 12431995 12813044 12887891 15143057 15870274 19850933 20974803 20979579 23023376 25852190 26187466 27898060 9177193 9566925 N/A N/A OmniPath
PRKCZ GSK3B 11481324 14657655 16510873 17053159 25241761 27898060 inhibition,stimulant N/A OmniPath
PRKCZ RPS6KB1 16931574 27898060 stimulant N/A OmniPath
IRAK1 PRKCZ 11937546 27898060 N/A N/A OmniPath
PRKCZ PPP1R14A 15003508 27898060 N/A N/A OmniPath
PPP1R14A PRKCZ 15003508 27898060 N/A N/A OmniPath
PRKCZ IKBKB 10022904 10195894 10356400 10779355 27898060 9689078 stimulant N/A OmniPath
ADAP1 PRKCZ 12893243 27898060 N/A N/A OmniPath
PRKCZ ADAP1 12893243 27898060 N/A N/A OmniPath
KRT10 PRKCZ 11585925 27898060 N/A N/A OmniPath
PRKCZ PHGDH 23374352 27898060 N/A N/A OmniPath
PRKCZ NCF1 11145703 12056906 27898060 8089108 stimulant N/A OmniPath
PRKCZ AGER 21829704 27898060 N/A N/A OmniPath
AGER PRKCZ 21829704 27898060 N/A N/A OmniPath
PRKCZ NR0B2 23824184 27898060 N/A N/A OmniPath
PRKCZ SLC22A8 19028678 27898060 N/A N/A OmniPath
PRKCZ PARD3 12390250 27898060 stimulant N/A OmniPath
PRKCZ PAWR 11755531 16209943 27898060 8797824 N/A N/A OmniPath
PRKCZ WWC1 15081397 27898060 N/A N/A OmniPath
WWC1 PRKCZ 15081397 27898060 N/A N/A OmniPath
YWHAB PRKCZ 10620507 21900206 2190021 27898060 stimulant N/A OmniPath
PRKCZ YWHAB 10620507 21900206 27898060 9705322 N/A N/A OmniPath
PRKCZ PARD6B 11260256 12887891 14676191 25852190 26186194 27898060 N/A N/A OmniPath
PARD6B PRKCZ 11260256 12887891 14676191 25852190 26186194 27898060 N/A N/A OmniPath
PRKCZ RPS6KB2 12529391 27898060 N/A N/A OmniPath
PRKCZ F11R 17057644 25241761 27898060 N/A N/A OmniPath
C1QBP PRKCZ 10831594 23402259 25852190 27898060 N/A N/A OmniPath
PRKCZ HABP4 14699138 27898060 inhibition N/A OmniPath
PRKCZ NR1H4 18668687 27898060 stimulant N/A OmniPath
PRKCZ PARD6A 10873802 11260256 12813044 14676191 14685273 15254234 16189514 16510873 17057644 17335965 17350623 25852190 27898060 N/A N/A OmniPath
PARD6A PRKCZ 10873802 11260256 12813044 14676191 14685273 15254234 16189514 16510873 17057644 17335965 17350623 25852190 27898060 N/A N/A OmniPath
PRKCZ PIK3CG 16527821 27898060 N/A N/A OmniPath
PRKCZ ADD1 15611095 27898060 8810272 9679146 stimulant N/A OmniPath
PRKCZ MARK3 15084291 27898060 inhibition N/A OmniPath
PRKCZ CHAT 12486117 15381704 27898060 stimulant N/A OmniPath
PRKCZ SMARCD3 23219531 27898060 N/A N/A OmniPath
PRKCZ ADD2 16116087 27898060 inhibition N/A OmniPath
PRKCZ OCLN 21545357 27898060 N/A N/A OmniPath
PRKCZ RND3 23622247 27898060 N/A N/A OmniPath
PRKCZ AQP9 17346701 21873454 27898060 stimulant N/A OmniPath
PRKCZ GEM 14701738 17605761 27898060 N/A N/A OmniPath
PRKCZ RRAD 27898060 9677319 N/A N/A OmniPath

Visualization










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