GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
SRPX
FullNmae
sushi repeat containing protein X-linked
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:11309
EnsembleID
ENSG00000101955
Uniprot
P78539
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
SRPX
lysosomal_cd
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
SRPX
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
SRPX
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
SRPX
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
SRPX
GO:0001845,GO:0005201,GO:0005515,GO:0005776,GO:0005783,GO:0006914,GO:0007155,GO:0009986,GO:0016020,GO:0034976,GO:0060244,GO:0062023,GO:2001241
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
AR
SRPX
20610535
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
SMARCA4
SRPX
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
SRPX
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
SRPX
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
GATA2
SRPX
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXP2
SRPX
20858596
trascriptional regulation,stimulation
inferred by curator
TFlink
TWIST1
SRPX
19051271
trascriptional regulation,stimulation
inferred by curator
TFlink
TWIST2
SRPX
19051271
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS000003ABC4
SRPX
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
KCTD13
SRPX
19615732
24234451
25348397
physical association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
CUL3
SRPX
25348397
N/A
physical interaction
ComPPI
PLK1
SRPX
19596235
24234451
25348397
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MAP1LC3A
SRPX
20562859
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
SLX4
SRPX
19596235
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
Visualization