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GENE：SST

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SST
FullNmae somatostatin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11329
EnsembleID ENSG00000157005
Uniprot P61278

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SST immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SST apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SST apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SST GO:0005179,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0006972,GO:0007166,GO:0007186,GO:0007267,GO:0007268,GO:0007584,GO:0007586,GO:0008285,GO:0008628,GO:0009410,GO:0010447,GO:0030334,GO:0043025,GO:0043200,GO:0048545,GO:0098982,GO:0098992,GO:0099072

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SST hsa:6750 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
SST hsa:6750 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
SST hsa:6750 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
SST hsa:6750 path:hsa04971 Gastric acid secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 SST 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 SST 19559773 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SST 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SST 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SSTR2 SST 1346068 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SSTR5 SST 14525934 25348397 7908405 N/A experimental interaction detection,in vivo ComPPI,HPRD
SSTR1 SST 1346068 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SST SSTR3 1337145 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SST PDIA2 25348397 N/A physical interaction ComPPI
SST SSTR2 1346068 27898060 8702767 stimulant N/A OmniPath
SST SSTR5 27898060 7908405 8769372 stimulant N/A OmniPath

Visualization










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