Gene Information gene info

GENE:STK25

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STK25
FullNmae serine/threonine kinase 25
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11404
EnsembleID ENSG00000115694
Uniprot O00506

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STK25 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STK25 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
STK25 GO:0004672,GO:0004674,GO:0005515,GO:0005524,GO:0005737,GO:0005737,GO:0005794,GO:0006468,GO:0006468,GO:0006979,GO:0007163,GO:0007165,GO:0007409,GO:0032874,GO:0036481,GO:0042542,GO:0042803,GO:0046777,GO:0046872,GO:0050772,GO:0051645,GO:0051683,GO:0070062,GO:0090168,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG STK25 20098747 23180781 physical association protein array InnateDB
APP STK25 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
PPP2R1A STK25 20005715 interaction type N/A PSP
YWHAZ STK25 20005715 interaction type N/A PSP
YWHAZ STK25 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 STK25 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF STK25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STK25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 STK25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 STK25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF STK25 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 STK25 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F373E STK25 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 STK25 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 STK25 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 STK25 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 STK25 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 STK25 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000048B5E9 STK25 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B83FE STK25 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STK25 CCM2 22135298 phosphorylation N/A PhosphoSite
STK25 PDCD10 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GOLGA2 STK25 14525934 15037601 23455922 24234451 25348397 25416956 26871637 27107012 association,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
MOS STK25 25348397 N/A physical interaction ComPPI
DYNLL1 STK25 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 STK25 25348397 N/A physical interaction ComPPI
PPP2R1A STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 STK25 25348397 N/A physical interaction ComPPI
STRN STK25 18782753 23455922 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
C4ORF19 STK25 25348397 N/A physical interaction ComPPI
PDCD10 STK25 14525934 16189514 17657516 18782753 21516116 23455922 23665169 24234451 25348397 25416956 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,two hybrid,cosedimentation in solution,molecular sieving,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,protein kinase assay,tandem affinity purification,surface plasmon resonance array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CCNDBP1 STK25 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAZ STK25 14525934 15037601 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro ComPPI,HPRD,IntAct
STRN3 STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PPP2CB STK25 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP2CA STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PKM STK25 25348397 N/A protein kinase assay ComPPI
KIF20A STK25 25348397 N/A physical interaction ComPPI
RPL12 STK25 25348397 N/A physical interaction ComPPI
ZDHHC17 STK25 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TCP1 STK25 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAOK2 STK25 25348397 N/A physical interaction ComPPI
PTPN13 STK25 25348397 N/A phosphatase assay ComPPI
NEDD4 STK25 25348397 N/A physical interaction ComPPI
UBE2D3 STK25 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GORASP1 STK25 25348397 N/A physical interaction ComPPI
STK24 STK25 17353931 18782753 23455922 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STRN4 STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
TRIM27 STK25 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP2R1B STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
TRAF3IP3 STK25 18782753 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAB39 STK25 21423148 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAOK1 STK25 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MOB4 STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
EIF4A3 STK25 25348397 N/A physical interaction ComPPI
MTMR6 STK25 25348397 N/A physical interaction ComPPI
STK25 STRIP1 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK25 SIKE1 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STK25 STRIP2 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STK25 FGFR1OP2 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STK25 USP36 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK25 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
STK25 LRRK2 25348397 N/A physical interaction ComPPI
STK25 APP 25348397 N/A physical interaction ComPPI
STK25 ACACA 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
STK25 CTTNBP2 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STK25 CEP70 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STK25 IHO1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STK25 ACAD11 25348397 N/A physical interaction ComPPI
STK25 MTPAP 25348397 N/A physical interaction ComPPI
STK25 ARV1 25348397 N/A physical interaction ComPPI
STK25 HBS1L 25348397 N/A physical interaction ComPPI
STK25 ZNF598 25348397 N/A physical interaction ComPPI
STK25 ARL13B 25348397 N/A physical interaction ComPPI
STK25 PROSER2 25348397 N/A physical interaction ComPPI
STK25 CCM2 17657516 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
STK25 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STK25 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
STK26 STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SLMAP STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CTTNBP2NL STK25 18782753 23455922 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
HSCB STK25 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
STK25 STK25 14525934 15037601 24234451 phosphorylation reaction protein kinase assay,two hybrid HPRD,IntAct
PTPN13 STK25 17657516 27898060 inhibition N/A OmniPath
IKBKG STK25 20098747 27898060 N/A N/A OmniPath
STK25 CCM2 17657516 22782892 27898060 N/A N/A OmniPath

Visualization