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GENE：STK4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STK4
FullNmae serine/threonine kinase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11408
EnsembleID ENSG00000101109
Uniprot Q13043

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STK4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STK4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STK4 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
STK4 GO:0000287,GO:0000902,GO:0001569,GO:0001841,GO:0001934,GO:0003157,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006468,GO:0006468,GO:0006606,GO:0006606,GO:0006915,GO:0007165,GO:0007417,GO:0008625,GO:0016604,GO:0018105,GO:0030216,GO:0032092,GO:0032991,GO:0033138,GO:0035265,GO:0035329,GO:0035329,GO:0035556,GO:0035556,GO:0042802,GO:0042803,GO:0043065,GO:0043408,GO:0043539,GO:0045600,GO:0046621,GO:0046777,GO:0050673,GO:0050680,GO:0050821,GO:0051262,GO:0060070,GO:0060215,GO:0060706,GO:0060800,GO:0061629,GO:0090090,GO:0097284,GO:0106310,GO:1902043,GO:1903945,GO:1904237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STK4 hsa:6789 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
STK4 hsa:6789 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
STK4 hsa:6789 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
STK4 hsa:6789 path:hsa05200 Pathways in cancer - Homo sapiens (human)
STK4 hsa:6789 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKT1 STK4 19940129 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
STK4 STK4 15688006 16930133 21808241 23431053 24243840 26467481 29145629 8702870 phosphorylation reaction,physical association,up-regulates inferred by curator Reactome,Signor
STK4 SAV1 11278283 15109305 16930133 29145629 8702870 9545236 physical association inferred by curator Reactome
LATS1 STK4 11278283 15688006 29145629 9545236 enzymatic reaction inferred by curator Reactome
STK4 LATS2 11278283 15688006 29145629 9545236 enzymatic reaction inferred by curator Reactome
STK4 MOB1B 11278283 15688006 18328708 29145629 9545236 enzymatic reaction inferred by curator Reactome
STK4 MOB1A 11278283 15688006 18328708 29145629 9545236 enzymatic reaction inferred by curator Reactome
STK4 MAP2K4 23331499 9182538 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CNKSR1 STK4 20005715 interaction type N/A PSP,SignaLink
YWHAG STK4 20005715 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
AR STK4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 STK4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 STK4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 STK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EZH2 STK4 24499724 trascriptional regulation,stimulation inferred by curator TFlink
MYC STK4 24499724 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STK4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 STK4 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 STK4 15685193 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection TarBase
URS0000324096 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003676C9 STK4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E STK4 24752237 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000023133F STK4 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 STK4 22291592 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F6 STK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 STK4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 STK4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 STK4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 STK4 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 STK4 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A760 STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 STK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 STK4 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F STK4 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC STK4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 STK4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 STK4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 STK4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 STK4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000079D48 STK4 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS0000098B3B STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009EA8F STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000042619A STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BB229 STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD6DC STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000065FDF STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004BACE STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AA845 STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D50C STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004283FE STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001A7A STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075994C STK4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000435A77 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001925C1 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000237E04 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B989F STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075E2C3 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075AB35 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000284586 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000031BC7D STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000259AE4 STK4 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 STK4 22135298 phosphorylation N/A PhosphoSite
ABL1 STK4 22135298 phosphorylation N/A PhosphoSite
STK4 BECN1 22135298 phosphorylation N/A PhosphoSite
STK4 PRDX1 22135298 phosphorylation N/A PhosphoSite
STK4 TNNI3 22135298 phosphorylation N/A PhosphoSite
STK4 STK4 22135298 phosphorylation N/A PhosphoSite
STK4 ABL1 22135298 phosphorylation N/A PhosphoSite
STK4 FOXO3 22135298 phosphorylation N/A PhosphoSite
STK4 IRF3 22135298 phosphorylation N/A PhosphoSite
STK4 AURKB 22135298 phosphorylation N/A PhosphoSite
STK4 MOB1B 22135298 phosphorylation N/A PhosphoSite
STK4 ITGA2 22135298 phosphorylation N/A PhosphoSite
STK4 H2BC3 22135298 phosphorylation N/A PhosphoSite
STK4 STK38 22135298 phosphorylation N/A PhosphoSite
STK4 H2AX 22135298 phosphorylation N/A PhosphoSite
MAPK8 STK4 22135298 phosphorylation N/A PhosphoSite
AKT1 STK4 22135298 phosphorylation N/A PhosphoSite
STK4 RASSF2 25361965 interaction type N/A PTMCode2
RASSF2 STK4 25361965 interaction type N/A PTMCode2
RASSF1 STK4 25361965 interaction type N/A PTMCode2
STK4 RASSF1 25361965 interaction type N/A PTMCode2
CASP3 STK4 25361965 interaction type N/A PTMCode2
STK4 CASP3 25361965 interaction type N/A PTMCode2
MST1 STK4 25361965 interaction type N/A PTMCode2
STK4 MST1 25361965 interaction type N/A PTMCode2
SAV1 STK4 25361965 interaction type N/A PTMCode2
STK4 SAV1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 STK4 25348397 N/A physical interaction ComPPI
DAXX STK4 25348397 N/A physical interaction ComPPI
HSPA8 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HSPA2 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DRG1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CEP43 STK4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ANXA1 STK4 23386615 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STAT1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GABARAPL2 STK4 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
YWHAG STK4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RASSF5 STK4 11864565 14525934 15109305 16892067 20562859 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,cross-linking study,experimental interaction detection,molecular sieving,nuclear magnetic resonance,physical interaction,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
MAP1LC3B STK4 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
STRN STK4 24234451 24255178 24366813 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
S100A13 STK4 25348397 N/A physical interaction ComPPI
EGLN3 STK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB8A STK4 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CASP3 STK4 11278283 11278782 14525934 24234451 25241761 25348397 9545236 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
ARHGAP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
VAPA STK4 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLG STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GTF2I STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
KPNB1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GAPDH STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STRN3 STK4 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UBB STK4 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
HSP90AA1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MAP1S STK4 23455922 24234451 24255178 24366813 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
BTRC STK4 25348397 N/A physical interaction ComPPI
COPB1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
COPA STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ILK STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PARP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
XRCC5 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PIGR STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MAP2K4 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
XPO6 STK4 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA5 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HSPA1A STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HSPA1B STK4 25348397 N/A tandem affinity purification ComPPI
FEN1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MSH6 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PRDX1 STK4 23386615 24234451 25348397 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,protein kinase assay,tandem affinity purification ComPPI,IntAct
THAP12 STK4 12384512 14525934 24234451 24255178 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
AKAP12 STK4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
XRCC6 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HDLBP STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBA4A STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
IQGAP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DDX5 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
LTF STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SPTAN1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PABPC1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SQSTM1 STK4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PKM STK4 23386615 24234451 25348397 association protein kinase assay,tandem affinity purification ComPPI,IntAct
IQGAP2 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
KIF3B STK4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ERC1 STK4 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
H2BC21 STK4 25348397 N/A physical interaction ComPPI
XPO1 STK4 23386615 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CLTC STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HUWE1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RPS18 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RPL4 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RANGAP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ADCYAP1 STK4 25348397 N/A physical interaction ComPPI
IPO7 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
VAPB STK4 25348397 N/A physical interaction ComPPI
MBP STK4 14525934 25348397 7665586 N/A experimental interaction detection,in vitro ComPPI,HPRD
TCP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CCT7 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GABARAP STK4 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RASSF1 STK4 14525934 15109305 20562859 23386615 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
RASSF2 STK4 20562859 20920251 23386615 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
HSPB1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CTNNB1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MAP1LC3A STK4 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HSPA9 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CSN1S1 14525934 25348397 7665586 N/A experimental interaction detection,in vitro ComPPI,HPRD
STK4 LATS1 14525934 15688006 24012335 24234451 25348397 colocalization experimental interaction detection,fluorescence microscopy,in vitro ComPPI,HPRD,IntAct
STK4 SAV1 14525934 16930133 20562859 20920251 23386615 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,nuclear magnetic resonance,physical interaction,in vitro,in vivo,tandem affinity purification,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
STK4 CNKSR1 25348397 N/A physical interaction ComPPI
STK4 SLX4IP 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 STK3 20562859 20920251 23386615 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
STK4 RASSF4 20562859 20920251 23455922 24234451 24366813 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,tandem affinity purification ComPPI,IntAct
STK4 MAP1B 20562859 23455922 24234451 24366813 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
STK4 TAOK1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 SIRT1 25348397 N/A physical interaction ComPPI
STK4 ABL1 25348397 N/A physical interaction ComPPI
STK4 FOXO3 25348397 N/A physical interaction ComPPI
STK4 H2AX 25348397 N/A physical interaction ComPPI
STK4 NEDD4 25348397 N/A physical interaction ComPPI
STK4 ELAVL1 25348397 N/A physical interaction ComPPI
STK4 AKT1 17932490 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
STK4 SGMS1 25348397 N/A physical interaction ComPPI
STK4 IL2RG 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STK4 RASSF3 20920251 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
STK4 LATS2 25348397 N/A physical interaction ComPPI
STK4 MOB1A 21516123 23386615 24234451 24255178 25348397 phosphorylation reaction,colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,protein kinase assay,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
STK4 MOB1B 22863277 24234451 24255178 25348397 phosphorylation reaction,colocalization,association anti tag coimmunoprecipitation,physical interaction,protein kinase assay,proximity-dependent biotin identification ComPPI,IntAct
STK4 AURKB 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 STRIP1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 FGFR1OP2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 KIF2A 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 KIF2C 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 MOB4 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 SH3GLB2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 SNX5 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 STRN4 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STK4 CDK3 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
STK4 FBXW11 25348397 N/A physical interaction ComPPI
STK4 RASSF6 20920251 24234451 24366813 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
STK4 CDC37 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK4 TP53 12384512 12942774 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
STK4 KIF2B 25348397 N/A physical interaction ComPPI
STK4 ZNF133 25348397 N/A physical interaction ComPPI
STK4 ZNF695 25348397 N/A physical interaction ComPPI
STK4 DYRK2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
STK4 KIF3C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
STK4 FOXO1 25348397 N/A physical interaction,protein kinase assay ComPPI
STK4 GABARAPL1 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
STK4 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
STK4 PIH1D1 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
STK4 PARVB 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
STK4 SPATA5L1 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
STK4 SOD2 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
STK4 TUBB6 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MCCC2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 IGHA1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ALB 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 TUBA1C 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 COA1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 AZGP1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 TUBA3C 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 HSPA6 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 TUBB1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 H1-2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MCCC1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 TGM3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 IGLC1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ANXA2P2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CALML5 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 HAL 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ACTBL2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 GGCT 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 HSPA1L 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 HSPA7 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 LCN1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 NCCRP1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ACACA 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 JCHAIN 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 EIF3CL 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 PHGDH 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MSH2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 COPG1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MCM4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 IPO5 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MCM3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ARHGAP18 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 PTBP1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 SNRNP200 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CCT8 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CCT3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CSE1L 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 SRP54 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 DUSP9 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 RANBP2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 SULT1A1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CAND1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 CKAP5 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 RPS3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MCM7 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 MTHFD1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 ARF1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 EIF3B 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 EPPK1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 DNAJA1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 NCL 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 RPS4X 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 STAT3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 PRDX2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 PAK3 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 IPO4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 DDX3X 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ZRSR2 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ARF4 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CSRP2 STK4 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
EEF1A2 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SLMAP STK4 23386615 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,confocal microscopy,proximity-dependent biotin identification ComPPI,IntAct
CTTNBP2NL STK4 25348397 N/A physical interaction ComPPI
SMR3B STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 STK4 11278782 12223493 14525934 20562859 23386615 24234451 8702870 physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection HPRD,IntAct
STK4 TNNI3 18986304 27898060 stimulant N/A OmniPath
STK4 AURKB 18243099 18767990 19203582 21554500 24814515 25298395 25402682 25892238 26460953 27898060 N/A N/A OmniPath
STK4 FOXO4 18394876 27898060 stimulant N/A OmniPath
STK4 FOXO3 16751106 18394876 18985696 22898666 27898060 stimulant N/A OmniPath
MST1 STK4 11805089 27898060 stimulant N/A OmniPath
CASP3 STK4 11278283 11278782 25241761 27898060 9545236 stimulant N/A OmniPath
STK4 H2BC11 12757711 27898060 N/A N/A OmniPath
STK4 FOXO1 18394876 18786403 21245099 22898666 27898060 stimulant N/A OmniPath
AKT1 STK4 17726016 17932490 19369195 19940129 22619175 23431053 23893242 27898060 inhibition N/A OmniPath
STK4 AKT1 17932490 19940129 27898060 N/A N/A OmniPath
STK4 MAP2K4 27898060 9182538 stimulant N/A OmniPath
STK4 ACACA 27898060 2900138 7907095 N/A N/A OmniPath
STK4 H2BC5 12757711 27898060 N/A N/A OmniPath
ABL1 STK4 21715626 27898060 N/A N/A OmniPath
STK4 ABL1 18794806 21715626 27898060 inhibition N/A OmniPath
PPP1CB STK4 21199877 27898060 N/A N/A OmniPath
STK4 LATS1 15688006 24012335 27898060 stimulant N/A OmniPath
RAF1 STK4 22898666 27898060 inhibition N/A OmniPath
PHLPP1 STK4 20513427 23431053 27898060 stimulant N/A OmniPath
STK4 AR 21512132 27898060 N/A N/A OmniPath
STK4 BECN1 24141421 27898060 N/A N/A OmniPath
PPP1CA STK4 21199877 27898060 N/A N/A OmniPath
AKT3 STK4 23431053 27898060 inhibition N/A OmniPath
STK4 LATS2 21808241 23431053 24255178 26578655 27898060 stimulant N/A OmniPath
PPP2CA STK4 21199877 23431053 27898060 inhibition N/A OmniPath
AKT2 STK4 23431053 27898060 inhibition N/A OmniPath
RASSF1 STK4 15109305 17598981 20562859 21808241 22683405 23455922 24255178 24366813 26186194 26578655 27898060 stimulant N/A OmniPath
MAPK8 STK4 20028971 27898060 stimulant N/A OmniPath
TAOK2 STK4 23431053 27898060 stimulant N/A OmniPath
TAOK1 STK4 23431053 27898060 stimulant N/A OmniPath
STK4 SAV1 16930133 17517604 20562859 20920251 21084559 23386615 23455922 24255178 24366813 25692647 26186194 27898060 stimulant N/A OmniPath
SAV1 STK4 16930133 17517604 20562859 20920251 21084559 23386615 23455922 24255178 24366813 25692647 26186194 27898060 stimulant N/A OmniPath
STK4 POLDIP3 15341740 27898060 N/A N/A OmniPath
PPP1CC STK4 21199877 27898060 N/A N/A OmniPath
STK4 MOB1B 18328708 19919647 21808241 22863277 23431053 24255178 27898060 stimulant N/A OmniPath
STK4 MOB1A 21808241 23386615 23431053 24255178 27898060 stimulant N/A OmniPath
PHLPP2 STK4 20513427 27898060 stimulant N/A OmniPath
PPP2CB STK4 21199877 27898060 N/A N/A OmniPath
TAOK3 STK4 23431053 27898060 stimulant N/A OmniPath
STK4 H2BC3 12757711 16462032 19747733 21212262 27898060 stimulant N/A OmniPath
STK4 H2BC14 12757711 27898060 N/A N/A OmniPath
STK4 PRM2 27898060 8218377 N/A N/A OmniPath
STK4 H2BC4 12757711 27898060 N/A N/A OmniPath
STK4 H2BU1 12757711 27898060 N/A N/A OmniPath
STK4 H2BC19P 12757711 27898060 N/A N/A OmniPath
STK4 H2BS1 12757711 27898060 N/A N/A OmniPath
STK4 H2BC15 12757711 27898060 N/A N/A OmniPath
STK4 H2BC17 12757711 27898060 N/A N/A OmniPath
STK4 H2BC18 12757711 27898060 N/A N/A OmniPath
STK4 H2BC13 12757711 27898060 N/A N/A OmniPath
STK4 H2BC9 12757711 27898060 N/A N/A OmniPath
STK4 H2BC21 12757711 19940129 21572393 27898060 N/A N/A OmniPath
STK4 H2BC12 12757711 27898060 N/A N/A OmniPath
STK4 H2BC20P 12757711 27898060 N/A N/A OmniPath

Visualization










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