GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
TM2D1
FullNmae
TM2 domain containing 1
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:24142
EnsembleID
ENSG00000162604
Uniprot
Q9BX74
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
TM2D1
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
TM2D1
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
TM2D1
GO:0001540,GO:0004930,GO:0005515,GO:0005886,GO:0007186,GO:0097190
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
TM2D1
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA2
TM2D1
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
FOXP3
TM2D1
20554955
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
SMARCA4
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TAL1
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TP53
TM2D1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
ELAVL1
TM2D1
25348397
N/A
physical interaction
ComPPI
TM2D1
APP
11278849
14525934
25348397
N/A
experimental interaction detection,physical interaction,two hybrid
ComPPI,HPRD
Source
Target
Pmid
Interactiontype
Methods
Database
URS00009B7568
TM2D1
27087310
direct interaction,inhibition
N/A
NPInter
Visualization