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GENE：TMBIM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMBIM1
FullNmae transmembrane BAX inhibitor motif containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23410
EnsembleID ENSG00000135926
Uniprot Q969X1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMBIM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMBIM1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMBIM1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMBIM1 GO:0005123,GO:0005515,GO:0005765,GO:0005765,GO:0005783,GO:0005794,GO:0005794,GO:0005886,GO:0010008,GO:0016020,GO:0035579,GO:0043086,GO:0043231,GO:0070062,GO:1902042,GO:1902045,GO:1903077,GO:2000504,GO:2001234

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 TMBIM1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TMBIM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TMBIM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TMBIM1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TMBIM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TMBIM1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TMBIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 TMBIM1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
BIK TMBIM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGFR TMBIM1 25348397 N/A physical interaction ComPPI
RCHY1 TMBIM1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS5 TMBIM1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRPRB TMBIM1 25348397 N/A physical interaction ComPPI
CD33 TMBIM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NXF1 TMBIM1 25348397 N/A physical interaction ComPPI
MOV10 TMBIM1 25348397 N/A physical interaction ComPPI
F2RL1 TMBIM1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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