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GENE：TMEM109

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMEM109
FullNmae transmembrane protein 109
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28771
EnsembleID ENSG00000110108
Uniprot Q9BVC6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMEM109 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM109 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM109 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM109 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMEM109 GO:0003674,GO:0005515,GO:0005640,GO:0022843,GO:0033017,GO:0034220,GO:0034765,GO:0042771,GO:0043069,GO:0070062,GO:0071480,GO:0071480

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMEM109 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TMEM109 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 TMEM109 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TMEM109 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TMEM109 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TMEM109 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB TMEM109 20371350 23824327 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000EED18 TMEM109 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000148B91 TMEM109 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 TMEM109 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E TMEM109 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA TMEM109 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 TMEM109 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C TMEM109 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D TMEM109 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F373E TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000014F13C TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB TMEM109 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000EF0B TMEM109 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000008A99 TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA TMEM109 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 TMEM109 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000011DF TMEM109 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001597DC TMEM109 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000214763 TMEM109 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000224AEA TMEM109 19536157 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000170D8B TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 TMEM109 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D TMEM109 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 TMEM109 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031BC7D TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000353492 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 TMEM109 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED TMEM109 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SH3GLB1 TMEM109 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CRYAB TMEM109 23542032 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRAF6 TMEM109 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LMNA TMEM109 25348397 N/A physical interaction ComPPI
MCM2 TMEM109 25348397 N/A physical interaction ComPPI
AQP9 TMEM109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN TMEM109 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
FAP TMEM109 25348397 N/A physical interaction ComPPI
KSR2 TMEM109 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB2A TMEM109 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC18A2 TMEM109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM25 TMEM109 25348397 N/A physical interaction ComPPI
PDZK1IP1 TMEM109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAR1A TMEM109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SDHA TMEM109 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GOLT1B TMEM109 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATL3 TMEM109 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TMEM109 CCRL2 25348397 N/A physical interaction ComPPI
AQP2 TMEM109 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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