Gene Information gene info

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GENE：TNFRSF25

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF25
FullNmae TNF receptor superfamily member 25
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11910
EnsembleID ENSG00000215788
Uniprot Q93038

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF25 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF25 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF25 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF25 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF25 GO:0005031,GO:0005576,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006915,GO:0007165,GO:0007166,GO:0033209,GO:0038023,GO:0042981,GO:0097190

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF25 hsa:8718 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TNFRSF25 TNFSF15 20403353 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CTCF TNFRSF25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNFRSF25 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAPK1 TNFRSF25 11606045 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DAP3 TNFRSF25 25348397 N/A physical interaction ComPPI
TNFRSF1A TNFRSF25 14525934 25348397 8934525 N/A two hybrid,two hybrid ComPPI,HPRD
TNFRSF25 TNFSF12 11094155 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNFRSF25 BAG4 14525934 25348397 9915703 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TNFRSF25 TNFSF15 11911831 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD
TNFRSF25 TRAF2 14525934 25348397 8875942 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TNFRSF25 TRADD 14525934 25348397 8934525 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TNFRSF25 RIPK1 25348397 N/A physical interaction ComPPI
FADD TNFRSF25 27898060 9052839 9430227 N/A N/A OmniPath
TNFRSF25 TRADD 14585074 21421854 27898060 8875942 8934525 9430227 9714541 stimulant N/A OmniPath
TNFSF15 TNFRSF25 11911831 14585074 20403353 21300286 27898060 stimulant N/A OmniPath

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