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GENE：TPD52L1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TPD52L1
FullNmae TPD52 like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12006
EnsembleID ENSG00000111907
Uniprot Q16890

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TPD52L1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPD52L1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPD52L1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPD52L1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TPD52L1 GO:0000086,GO:0005515,GO:0005737,GO:0005737,GO:0042802,GO:0042803,GO:0043406,GO:0043406,GO:0046330,GO:0048471,GO:2001235,GO:2001235

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TPD52L1 MAP3K5 14761963 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR TPD52L1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 TPD52L1 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 TPD52L1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TPD52L1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TPD52L1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 TPD52L1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 TPD52L1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C TPD52L1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TPD52L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TPD52L1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004DA9DB TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F TPD52L1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB TPD52L1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD TPD52L1 24398324 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TPD52L2 TPD52L1 14525934 25348397 9484778 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PSMC3 TPD52L1 25348397 N/A physical interaction ComPPI
MAL2 TPD52L1 11549320 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
YWHAB TPD52L1 12963375 14525934 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
YWHAZ TPD52L1 12963375 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MAP3K5 TPD52L1 14525934 14761963 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBR5 TPD52L1 25348397 N/A physical interaction ComPPI
YWHAQ TPD52L1 25348397 N/A physical interaction ComPPI
SFN TPD52L1 19732746 24234451 25348397 27898060 physical association two hybrid ComPPI,IntAct,OmniPath
TPD52L1 TPD52 14525934 24234451 25348397 9484778 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
TPD52L1 TPD52L3 14525934 16631610 24234451 25348397 physical association two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,IntAct
TPD52L1 EIF3J 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TPD52L1 GPR135 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TPD52L1 YAE1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TPD52L1 HDAC1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TPD52L1 ABL2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TPD52L1 PAK6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TPD52L1 ISYNA1 25348397 N/A physical interaction ComPPI
TPD52L1 UCHL3 25348397 N/A physical interaction ComPPI
TPD52L1 AZIN2 25348397 N/A physical interaction ComPPI
TPD52L1 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
NPM3 TPD52L1 25348397 N/A physical interaction ComPPI
TPD52L1 TPD52L1 14525934 24234451 9484778 physical association two hybrid,two hybrid HPRD,IntAct
TPD52L1 MAP3K5 14761963 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B966B TPD52L1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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