Gene Information gene info

  1. Home

GENE：TPT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TPT1
FullNmae tumor protein, translationally-controlled 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12022
EnsembleID ENSG00000133112
Uniprot P13693

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TPT1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPT1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPT1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TPT1 GO:0000922,GO:0003723,GO:0005509,GO:0005509,GO:0005515,GO:0005615,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005771,GO:0005829,GO:0005881,GO:0006816,GO:0006874,GO:0009615,GO:0019827,GO:0042981,GO:0043066,GO:0070062,GO:0140297,GO:1902230,GO:2000384

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TPT1 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
TPT1 SNX6 16730713 23180781 physical association anti tag coimmunoprecipitation InnateDB
TPT1 ATP1A1 16730713 23180781 physical association anti tag coimmunoprecipitation InnateDB
TPT1 EEF1A1 14623968 23180781 physical association anti tag coimmunoprecipitation InnateDB
TPT1 EEF1B2 14623968 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDK2 TPT1 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG TPT1 20098747 23180781 physical association protein array InnateDB
APP TPT1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR TPT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 TPT1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TPT1 19815065 trascriptional regulation,stimulation inferred by curator TFlink
MYC TPT1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFEC1 TPT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 TPT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 TPT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 TPT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001938D9 TPT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000753AD TPT1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 TPT1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B TPT1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 TPT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F TPT1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF1B TPT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG3 TPT1 25348397 N/A physical interaction ComPPI
CALM1 TPT1 25348397 N/A physical interaction ComPPI
BCL2L1 TPT1 15870695 25348397 27898060 N/A physical interaction ComPPI,OmniPath
DDIT4L TPT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMAD2 TPT1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
TBCB TPT1 25348397 N/A physical interaction ComPPI
RBBP6 TPT1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LIG4 TPT1 25348397 N/A physical interaction ComPPI
SPP1 TPT1 25348397 N/A physical interaction ComPPI
SNX6 TPT1 14525934 16730713 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
XRCC5 TPT1 22451927 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CALR TPT1 25348397 N/A physical interaction ComPPI
MCL1 TPT1 11598139 12149273 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PLK1 TPT1 12167714 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
XRCC6 TPT1 22451927 24234451 25348397 27607350 association,physical association anti bait coimmunoprecipitation,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EEF1A1 TPT1 14525934 14623968 24234451 25348397 27607350 association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ATM TPT1 22451927 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPLP1 TPT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 TPT1 25348397 N/A physical interaction ComPPI
ATP1A1 TPT1 14525934 15383549 16730713 21278788 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
TPT1 ATP1A2 14525934 15383549 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
TPT1 STEAP3 14525934 15319436 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
TPT1 MLC1 12149273 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
TPT1 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TPT1 FANCA 25348397 N/A physical interaction ComPPI
TPT1 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
TPT1 DBN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TPT1 TP53 21081126 22451927 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid pooling approach ComPPI,IntAct,OmniPath
TPT1 CDK2 25348397 N/A physical interaction ComPPI
TPT1 APP 25348397 N/A physical interaction ComPPI
TPT1 NKX3-1 25348397 N/A physical interaction ComPPI
TPT1 PER2 25348397 N/A physical interaction ComPPI
TPT1 TUBB2A 24234451 25348397 27607350 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TPT1 TRIP13 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TPT1 NOTCH3 25348397 N/A physical interaction ComPPI
TPT1 HSPB1 24234451 25277244 25348397 physical association anti bait coimmunoprecipitation,reverse ras recruitment system,physical interaction ComPPI,IntAct
TPT1 NPEPL1 25348397 N/A physical interaction ComPPI
TPT1 SAMD9 25348397 N/A physical interaction ComPPI
TPT1 MSH2 25348397 N/A physical interaction ComPPI
TPT1 MYCBP 25348397 N/A physical interaction ComPPI
TPT1 LACC1 25348397 N/A physical interaction ComPPI
TPT1 CST7 25348397 N/A physical interaction ComPPI
TPT1 FOXA1 25348397 N/A physical interaction ComPPI
TPT1 MCPH1 25348397 N/A physical interaction ComPPI
TPT1 H2AX 22451927 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TPT1 RHEB 17301792 24234451 25348397 27898060 N/A pull down,physical interaction,gdp/gtp exchange assay ComPPI,IntAct,OmniPath
TPT1 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TPT1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TPT1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TPT1 TSC22D1 18325344 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct,OmniPath
TPT1 CHFR 18504434 24234451 25348397 27898060 physical association two hybrid ComPPI,IntAct,OmniPath
TPT1 EGFR 21278788 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TPT1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TPT1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
EEF1D TPT1 14623968 15062873 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
EEF1B2 TPT1 25348397 N/A physical interaction ComPPI
EEF1A2 TPT1 25348397 N/A physical interaction ComPPI
TPT1 TPT1 11368327 12149273 14525934 N/A experimental interaction detection,two hybrid HPRD
TPT1 TUFM 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBB4B 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS20 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 SLC25A6 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 SLC25A5 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 SERPINH1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS8 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS7 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS5 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS4X 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBB 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBA8 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBA4A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBA3C 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 TUBA1C 24234451 27607350 association,physical association anti bait coimmunoprecipitation,bimolecular fluorescence complementation IntAct
TPT1 TRIM27 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 SRP14 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS3A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL7 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL7A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL6 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL4 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL38 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL30 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL27A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL22 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS3 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS25 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS2 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPS16 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPN1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPLP2 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPLP0 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL9 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PKM 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PHB 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PABPC4 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PABPC3 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PABPC1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 NAA50 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 MYL6 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 MYL12B 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL18A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL18 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL17 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL15 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL14 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RPL12 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RARS1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 PRDX1 24234451 27607350 association,physical association anti bait coimmunoprecipitation,bimolecular fluorescence complementation IntAct
TPT1 HSPA6 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 HSPA5 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 HSPA1L 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 HNRNPM 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 HNRNPK 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 H4C1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 H2AC4 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 GRN 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 LMNA 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 LDHA 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 KRT76 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 KRT73 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 KRT5 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 JUP 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 HSPA9 24234451 27607350 association,physical association anti bait coimmunoprecipitation,bimolecular fluorescence complementation IntAct
TPT1 HSPA8 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3H 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3G 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3F 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3E 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3D 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3C 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3B 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 GFAP 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 GAPDH 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 G3BP1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF4A1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3M 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3L 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3K 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3I 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 ACTA1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 RACK1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 YBX1 24234451 27607350 association,physical association anti bait coimmunoprecipitation,bimolecular fluorescence complementation IntAct
TPT1 DEK 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 DDX3X 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 CLCC1 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 CBS 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 ATP5F1B 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 ATP5F1A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TPT1 ACTB 24234451 27607350 association,physical association anti bait coimmunoprecipitation,bimolecular fluorescence complementation IntAct
PLK1 TPT1 12167714 17287340 18669648 20068231 27898060 inhibition,stimulant N/A OmniPath
IKBKG TPT1 20098747 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009C0DC3 TPT1 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return