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GENE：TRAF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRAF7
FullNmae TNF receptor associated factor 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20456
EnsembleID ENSG00000131653
Uniprot Q6Q0C0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRAF7 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRAF7 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TRAF7 GO:0000027,GO:0000151,GO:0004842,GO:0005515,GO:0005730,GO:0005886,GO:0006915,GO:0007219,GO:0008270,GO:0016567,GO:0016567,GO:0031410,GO:0043231,GO:0043410,GO:0043525,GO:0061630,GO:0070372,GO:2000060,GO:2001235

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RIPK4 TRAF7 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TRAF7 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TRAF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE TRAF7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000166778 TRAF7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 TRAF7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 TRAF7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B TRAF7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D TRAF7 25416803 26080425 mrna cleavage,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000302909 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003BBF48 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B2B5C TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000160683 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000486E0B TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000116F83 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000254A6 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018E6CD TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BE495 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000759B6A TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122F23 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F373E TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CCD18 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076E54 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B0B46 TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005194EC TRAF7 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CYLD TRAF7 25361965 interaction type N/A PTMCode2
TRAF7 CYLD 25361965 interaction type N/A PTMCode2
TRAF7 UBE2L3 25361965 interaction type N/A PTMCode2
UBE2L3 TRAF7 25361965 interaction type N/A PTMCode2
TRAF7 MAP3K3 25361965 interaction type N/A PTMCode2
MAP3K3 TRAF7 25361965 interaction type N/A PTMCode2
TRAF6 TRAF7 25361965 interaction type N/A PTMCode2
TRAF7 TRAF6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CORO1A TRAF7 25348397 N/A physical interaction ComPPI
OIP5 TRAF7 25348397 N/A physical interaction ComPPI
CD2BP2 TRAF7 25348397 N/A physical interaction ComPPI
LCA5 TRAF7 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 TRAF7 14525934 16230348 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBE2D1 TRAF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAC1 TRAF7 25348397 N/A physical interaction ComPPI
UBE2D4 TRAF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PFDN4 TRAF7 25348397 N/A physical interaction ComPPI
ABRAXAS2 TRAF7 25348397 N/A physical interaction ComPPI
EVL TRAF7 25348397 N/A physical interaction ComPPI
UBE2D2 TRAF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2L3 TRAF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNS2 TRAF7 25348397 N/A physical interaction ComPPI
MAP2K5 TRAF7 25348397 N/A physical interaction ComPPI
ODF2 TRAF7 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CLEC11A TRAF7 25348397 N/A physical interaction ComPPI
MMP10 TRAF7 25348397 N/A physical interaction ComPPI
UBE2K TRAF7 25348397 N/A physical interaction ComPPI
STAM TRAF7 25348397 N/A physical interaction ComPPI
UBE2D3 TRAF7 25348397 N/A physical interaction ComPPI
TRIM25 TRAF7 25348397 N/A physical interaction ComPPI
UBE2L6 TRAF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TINAG TRAF7 25348397 N/A physical interaction ComPPI
MAP3K2 TRAF7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DTNBP1 TRAF7 25348397 N/A physical interaction ComPPI
MAP3K3 TRAF7 14525934 14743216 15001576 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
IFT57 TRAF7 25348397 N/A physical interaction ComPPI
NELL2 TRAF7 25348397 N/A physical interaction ComPPI
FBXW11 TRAF7 25348397 N/A physical interaction ComPPI
RGCC TRAF7 25348397 N/A physical interaction ComPPI
SYBU TRAF7 25348397 N/A physical interaction ComPPI
TRAF7 CYLD 14525934 16230348 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRAF7 RIPK4 25348397 N/A physical interaction ComPPI
TRAF7 LIME1 25348397 N/A physical interaction ComPPI
TRAF7 RALYL 25348397 N/A physical interaction ComPPI
TRAF7 SP6 25348397 N/A physical interaction ComPPI
TRAF7 DEUP1 25348397 N/A physical interaction ComPPI
TRAF7 POU5F1 25348397 N/A physical interaction ComPPI
TRAF7 CERT1 25348397 N/A physical interaction ComPPI
TRAF7 FBXO28 25348397 N/A physical interaction ComPPI
TRAF7 IKBIP 25348397 N/A physical interaction ComPPI
TRAF7 FRMD1 25348397 N/A physical interaction ComPPI
TRAF7 COMMD10 25348397 N/A physical interaction ComPPI
TRAF7 TSPYL6 25348397 N/A physical interaction ComPPI
TRAF7 CGNL1 25348397 N/A physical interaction ComPPI
TRAF7 GPR156 25348397 N/A physical interaction ComPPI
TRAF7 ZNF764 25348397 N/A physical interaction ComPPI
ZNF263 TRAF7 25348397 N/A physical interaction ComPPI
TRIM44 TRAF7 25348397 N/A physical interaction ComPPI
TRAF7 TRAF7 14525934 14743216 24234451 physical association anti tag coimmunoprecipitation,experimental interaction detection HPRD,IntAct
MYB TRAF7 16162816 27898060 N/A N/A OmniPath
TRAF7 MAP3K3 14743216 15001576 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008BDDC3 TRAF7 27087310 direct interaction,inhibition N/A NPInter

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