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GENE：TRIM32

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRIM32
FullNmae tripartite motif containing 32
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16380
EnsembleID ENSG00000119401
Uniprot Q13049

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRIM32 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRIM32 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRIM32 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRIM32 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
TRIM32 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
TRIM32 GO:0000209,GO:0001894,GO:0003713,GO:0003723,GO:0004842,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005863,GO:0006511,GO:0008270,GO:0009411,GO:0010508,GO:0010994,GO:0016567,GO:0017022,GO:0030307,GO:0030335,GO:0030957,GO:0031369,GO:0032897,GO:0034612,GO:0042802,GO:0043123,GO:0043130,GO:0043621,GO:0044790,GO:0045087,GO:0045087,GO:0045444,GO:0045666,GO:0045732,GO:0045787,GO:0045862,GO:0045893,GO:0046716,GO:0048147,GO:0050769,GO:0051091,GO:0051092,GO:0051092,GO:0051092,GO:0051155,GO:0061564,GO:0061630,GO:0061630,GO:0070936,GO:1902230,GO:1903265,GO:1903883,GO:1903886,GO:2000147

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TRIM32 hsa:22954 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK1 TRIM32 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRIM32 STING1 23180781 25505063 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 TRIM32 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 TRIM32 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 TRIM32 18668040 22473208 25128227 25416803 26497687 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002075FA TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TRIM32 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PDE9A TRIM32 25361965 interaction type N/A PTMCode2
TRIM32 PDE9A 25361965 interaction type N/A PTMCode2
UBE2N TRIM32 25361965 interaction type N/A PTMCode2
TRIM32 UBE2N 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GEM TRIM32 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCTD9 TRIM32 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RARA TRIM32 25348397 N/A physical interaction ComPPI
NGB TRIM32 25348397 N/A physical interaction ComPPI
RNF208 TRIM32 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VPS11 TRIM32 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
YWHAG TRIM32 25348397 N/A physical interaction ComPPI
ATXN1 TRIM32 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
XIAP TRIM32 21628460 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIM32 SCGB1A1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 RABAC1 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
TRIM32 UBQLN1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
TRIM32 PDE9A 14525934 16189514 19060904 24234451 25348397 25416956 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
TRIM32 ABI2 18632609 24234451 25348397 25416956 27898060 physical association two hybrid,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
TRIM32 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
TRIM32 SFN 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM32 MID2 25348397 N/A physical interaction ComPPI
TRIM32 TRIM23 25348397 N/A physical interaction ComPPI
TRIM32 TRIM27 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM32 UBE2N 17994549 19549727 19690564 21143188 24234451 25348397 27173435 27898060 association,physical association two hybrid,physical interaction,two hybrid array,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct,OmniPath
TRIM32 PIAS3 25348397 N/A physical interaction ComPPI
TRIM32 UBE2V1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 UBE2U 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 PIAS4 25348397 N/A physical interaction ComPPI
TRIM32 IRAK1 25348397 N/A physical interaction ComPPI
TRIM32 BIRC2 25348397 N/A physical interaction ComPPI
TRIM32 BIRC3 25348397 N/A physical interaction ComPPI
TRIM32 PIDD1 25348397 N/A physical interaction ComPPI
TRIM32 RXRA 25348397 N/A physical interaction ComPPI
TRIM32 UBE2E1 25348397 N/A physical interaction ComPPI
TRIM32 UBE2V2 25348397 N/A physical interaction ComPPI
TRIM32 UBE2D2 25348397 N/A physical interaction ComPPI
TRIM32 UBE2D3 25348397 N/A physical interaction ComPPI
TRIM32 STING1 25348397 N/A physical interaction ComPPI
TRIM32 DDX58 25348397 N/A physical interaction ComPPI
TRIM32 DTNBP1 25348397 N/A physical interaction ComPPI
TRIM32 TOP1 25348397 N/A physical interaction ComPPI
TRIM32 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM32 UBC 25348397 N/A physical interaction ComPPI
TRIM32 HSP90AA1 25348397 N/A physical interaction ComPPI
TRIM32 HSP90AA2P 25348397 N/A physical interaction ComPPI
TRIM32 YWHAH 25348397 N/A physical interaction ComPPI
TRIM32 YWHAB 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM32 YWHAE 25348397 N/A physical interaction ComPPI
TRIM32 YWHAZ 25348397 N/A physical interaction ComPPI
TRIM32 TP73 25348397 N/A physical interaction ComPPI
TRIM32 TRIM5 22493164 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM32 RNF41 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM32 GLIS2 24500717 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIM32 GPRASP2 25348397 N/A physical interaction ComPPI
TRIM32 CEP250 25348397 N/A physical interaction ComPPI
TRIM32 CUL3 25348397 N/A physical interaction ComPPI
TRIM32 MYCN 25348397 N/A physical interaction ComPPI
TRIM32 TP53 25348397 N/A physical interaction ComPPI
TRIM32 PTPN11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 CLIP4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 PTCD2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 SYT6 25348397 N/A physical interaction ComPPI
TRIM32 SRPRB 25348397 N/A physical interaction ComPPI
TRIM32 AKTIP 23414517 24234451 25348397 physical association physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
TRIM32 EPN3 25348397 N/A physical interaction ComPPI
TRIM32 FAM189A2 25348397 N/A physical interaction ComPPI
TRIM32 SEPTIN6 25348397 N/A physical interaction ComPPI
TRIM32 FBXW11 25348397 N/A physical interaction ComPPI
TRIM32 DNAJC7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM32 TUBA1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM32 MCM2 25348397 N/A physical interaction ComPPI
TRIM32 NDRG2 25348397 N/A physical interaction ComPPI
TRIM32 TRIM72 25348397 N/A physical interaction ComPPI
TRIM32 SEC23IP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TRIM32 EXOC1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TRIM32 TULP2 25348397 N/A physical interaction ComPPI
TRIM32 FAM189B 25348397 N/A physical interaction ComPPI
TRIM32 TKT 25348397 N/A physical interaction ComPPI
TRIM32 P4HA2 25348397 N/A physical interaction ComPPI
TRIM32 CRYL1 25348397 N/A physical interaction ComPPI
TRIM32 TRPC4AP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TRIM32 EXOC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TRIM32 APC 25348397 N/A physical interaction ComPPI
TRIM32 HSPA4 25348397 N/A physical interaction ComPPI
TRIM32 IQCB1 24234451 25348397 25552655 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM32 HSP90AB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TRIM32 TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
TRIM32 TUBA1A 24234451 25348397 27291054 association pull down ComPPI,IntAct
TRIM32 ERGIC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 GPR137B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 DERL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 FADS6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 MOB1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 PELI2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 LCN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 ICMT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM32 RAB29 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D1 TRIM32 25348397 N/A physical interaction ComPPI
UBE2E2 TRIM32 25348397 N/A physical interaction ComPPI
UBE2E3 TRIM32 25348397 N/A physical interaction ComPPI
YWHAQ TRIM32 25348397 N/A physical interaction ComPPI
TRIM32 TRIM32 11331580 14525934 22493164 24234451 25416956 physical association two hybrid array,two hybrid prey pooling approach,two hybrid HPRD,IntAct
IRAK1 TRIM32 21903422 27898060 N/A N/A OmniPath
TRIM32 STING1 22745133 25505063 27898060 N/A N/A OmniPath

Visualization










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