Gene Information gene info

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GENE：TXNDC12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TXNDC12
FullNmae thioredoxin domain containing 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24626
EnsembleID ENSG00000117862
Uniprot O95881

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TXNDC12 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TXNDC12 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TXNDC12 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TXNDC12 GO:0005515,GO:0005783,GO:0005788,GO:0015035,GO:0019153,GO:1902236

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TXNDC12 hsa:51060 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
TXNDC12 hsa:51060 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR TXNDC12 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TXNDC12 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TXNDC12 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TXNDC12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 TXNDC12 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 TXNDC12 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000D5659 TXNDC12 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000072E4C TXNDC12 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 TXNDC12 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F TXNDC12 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXLNA TXNDC12 25348397 N/A physical interaction ComPPI
SGTA TXNDC12 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXNDC12 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TXNDC12 TLN1 25348397 N/A physical interaction ComPPI
TXNDC12 NPM1 25348397 N/A physical interaction ComPPI
TXNDC12 UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXNDC12 ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TXNDC12 IQGAP2 25348397 N/A physical interaction ComPPI
TXNDC12 TUBGCP4 25348397 N/A physical interaction ComPPI
TXNDC12 TUBGCP5 25348397 N/A physical interaction ComPPI
TXNDC12 MZT2A 25348397 N/A physical interaction ComPPI
TXNDC12 TUBGCP6 25348397 N/A physical interaction ComPPI
TXNDC12 TUBGCP3 25348397 N/A physical interaction ComPPI
TXNDC12 TUBGCP2 25348397 N/A physical interaction ComPPI
TXNDC12 TUBG1 25348397 N/A physical interaction ComPPI
TXNDC12 PTPRO 25348397 N/A physical interaction ComPPI
TXNDC12 TRIM25 25348397 N/A physical interaction ComPPI
TXNDC12 CAMLG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXNDC12 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXNDC12 DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXNDC12 YTHDC1 24234451 30021884 physical association cross-linking study IntAct

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