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GENE：UACA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UACA
FullNmae uveal autoantigen with coiled-coil domains and ankyrin repeats
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15947
EnsembleID ENSG00000137831
Uniprot Q9BZF9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UACA mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UACA apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UACA apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
UACA GO:0003674,GO:0003779,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0005856,GO:0008150,GO:0043280,GO:0070062,GO:1901223

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 UACA 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR UACA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UACA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 UACA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UACA 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 UACA 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UACA 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UACA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 UACA 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 UACA 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000041FA2C UACA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C UACA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075AB14 UACA 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE UACA 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MIS18A UACA 25348397 N/A physical interaction ComPPI
PNMA5 UACA 25348397 N/A physical interaction ComPPI
PPP1CB UACA 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KEAP1 UACA 25348397 N/A physical interaction ComPPI
KRT31 UACA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT40 UACA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BORCS6 UACA 25348397 N/A physical interaction ComPPI
PICK1 UACA 25348397 N/A physical interaction ComPPI
REL UACA 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
GRB2 UACA 12577067 24234451 25348397 association pull down ComPPI,IntAct
HIF1A UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1R12A UACA 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CDH1 UACA 25348397 N/A physical interaction ComPPI
VTN UACA 25348397 N/A physical interaction ComPPI
BAG6 UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WWP2 UACA 25348397 N/A physical interaction ComPPI
PRKAR1B UACA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPL UACA 25348397 N/A physical interaction ComPPI
RABEP1 UACA 25348397 N/A physical interaction ComPPI
UBQLN2 UACA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SYNCRIP UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF2 UACA 25348397 N/A physical interaction ComPPI
TP63 UACA 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
HIF1AN UACA 17003112 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
RGS3 UACA 25348397 N/A physical interaction ComPPI
MED14 UACA 14525934 15604093 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
SYNC UACA 25348397 N/A physical interaction ComPPI
STAMBP UACA 14525934 16730941 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MAP3K3 UACA 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CELSR3 UACA 12421765 14525934 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
SORT1 UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ANLN UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAN2 UACA 25348397 N/A physical interaction ComPPI
IFI16 UACA 25348397 N/A physical interaction ComPPI
MYH9 UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FUS UACA 25348397 N/A physical interaction ComPPI
NRDC UACA 25348397 N/A physical interaction ComPPI
NFKBIE UACA 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ZUP1 UACA 25348397 N/A physical interaction ComPPI
WIZ UACA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO25 UACA 25348397 N/A physical interaction ComPPI
GUCY1B1 UACA 25348397 N/A physical interaction ComPPI
AHCYL1 UACA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCAR1 UACA 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ANKRD28 UACA 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
USP48 UACA 25348397 N/A physical interaction ComPPI
PLEKHA7 UACA 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
JPH1 UACA 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
UACA TIGD7 25348397 N/A physical interaction ComPPI
UACA L1TD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UACA JPH4 25348397 N/A physical interaction ComPPI
UACA CORO6 25348397 N/A physical interaction ComPPI
UACA CCDC102B 25348397 N/A physical interaction ComPPI
UACA CCDC125 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VIM UACA 24234451 30021884 physical association cross-linking study IntAct
KRT8 UACA 24234451 30021884 physical association cross-linking study IntAct

Visualization










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