GENE：UMOD
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | UMOD |
| FullNmae | uromodulin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12559 |
| EnsembleID | ENSG00000169344 |
| Uniprot | P07911 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| UMOD | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| UMOD | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| UMOD | GO:0000922,GO:0002251,GO:0003091,GO:0003094,GO:0005509,GO:0005515,GO:0005615,GO:0005783,GO:0005796,GO:0005929,GO:0006629,GO:0006874,GO:0006883,GO:0006914,GO:0006954,GO:0006968,GO:0007029,GO:0007157,GO:0007159,GO:0008217,GO:0008285,GO:0008380,GO:0009410,GO:0009414,GO:0009986,GO:0015747,GO:0016020,GO:0016323,GO:0016324,GO:0016324,GO:0019864,GO:0019898,GO:0030433,GO:0030643,GO:0030644,GO:0032496,GO:0033209,GO:0033555,GO:0034620,GO:0035809,GO:0044861,GO:0046720,GO:0050829,GO:0051223,GO:0055075,GO:0060073,GO:0060170,GO:0061077,GO:0070062,GO:0070294,GO:0071918,GO:0072044,GO:0072051,GO:0072218,GO:0072221,GO:0072233,GO:0072665,GO:0097190,GO:0097709,GO:0097744,GO:0098552,GO:0140367,GO:1990266,GO:1990266 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CEBPA | UMOD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | UMOD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | UMOD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF1B | UMOD | 18846391 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MMP8 | UMOD | 14525934 25348397 27898060 8397318 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| UMOD | LTA | 14525934 25348397 27898060 8323280 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| UMOD | RSC1A1 | 25348397 | N/A | physical interaction | ComPPI |
| IL1B | UMOD | 27898060 9099704 | N/A | N/A | OmniPath |