GENE：USP47
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | USP47 |
| FullNmae | ubiquitin specific peptidase 47 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20076 |
| EnsembleID | ENSG00000170242 |
| Uniprot | Q96K76 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| USP47 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP47 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP47 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP47 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP47 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| USP47 | GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006284,GO:0006974,GO:0008630,GO:0009410,GO:0010972,GO:0016579,GO:0019005,GO:0030307,GO:0034644,GO:0035520,GO:0043066,GO:0043154,GO:0045892,GO:0071987,GO:0090263,GO:0101005,GO:1902230 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | USP47 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | USP47 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | USP47 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | USP47 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000EED18 | USP47 | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000009262D | USP47 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000029D9F1 | USP47 | 25416803 25429829 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS0000324096 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | USP47 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SF3A3 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| PAK2 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| RAD21 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1R8 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK14 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| CPNE1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| RHPN1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| BTRC | USP47 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SNX6 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| FEN1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| HDLBP | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| EEA1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| GRK5 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| MED9 | USP47 | 14525934 14638676 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| VAMP3 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| TCEA1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| HDAC6 | USP47 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VRK1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| AURKA | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| MDC1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| NCF2 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| ETF1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| SNCA | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| RECQL | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| TOMM34 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| CLPP | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| KIF22 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R5D | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| KATNA1 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| PSMD5 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| FBXW11 | USP47 | 19615732 24234451 25348397 25609649 | association,physical association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| KIFC3 | USP47 | 25253721 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| EZR | USP47 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| USP47 | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | UBXN1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | WRAP73 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | RBPJ | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| USP47 | AP5Z1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | FOXK1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| USP47 | FOXK2 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| USP47 | ATOH1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | INPP5K | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | LETM1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | CTNNBL1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | MCTS1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | NAA15 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | OTUB1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | TRMT2A | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | IST1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | RPRD1B | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | ADSL | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | LRRC40 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | DNAJC2 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | AVIL | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | PLS1 | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | FARSB | 25348397 | N/A | physical interaction | ComPPI |
| USP47 | HMGN5 | 25348397 | N/A | physical interaction | ComPPI |
| EEF1A2 | USP47 | 25348397 | N/A | physical interaction | ComPPI |
| PDIA6 | USP47 | 24234451 30021884 | physical association | cross-linking study | IntAct |