GENE:WFS1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | WFS1 |
FullNmae | wolframin ER transmembrane glycoprotein |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:12762 |
EnsembleID | ENSG00000109501 |
Uniprot | O76024 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
WFS1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
WFS1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
WFS1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
WFS1 | GO:0000122,GO:0001822,GO:0003091,GO:0005515,GO:0005516,GO:0005783,GO:0005783,GO:0005788,GO:0005789,GO:0005789,GO:0005789,GO:0006983,GO:0006983,GO:0007601,GO:0007605,GO:0017148,GO:0022417,GO:0030141,GO:0030425,GO:0030433,GO:0030433,GO:0030672,GO:0030968,GO:0031016,GO:0031398,GO:0031398,GO:0031625,GO:0032469,GO:0034976,GO:0042048,GO:0042593,GO:0043066,GO:0043069,GO:0043433,GO:0043524,GO:0045927,GO:0048306,GO:0050821,GO:0050821,GO:0050821,GO:0050821,GO:0050877,GO:0051117,GO:0051247,GO:0051928,GO:0055074,GO:0055074,GO:0070628,GO:0140297,GO:1902236,GO:1903573,GO:1903892,GO:1904294,GO:2000675 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
WFS1 | hsa:7466 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | WFS1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | WFS1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
TFAP2C | WFS1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | WFS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
XBP1 | WFS1 | 16539657 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
YIPF3 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
ITGB3BP | WFS1 | 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
PSMA5 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
CFTR | WFS1 | 17110338 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MAPK6 | WFS1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
EIF6 | WFS1 | 14525934 16169070 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
SYVN1 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
ATF6 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
ANTXR1 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
SMURF1 | WFS1 | 21454619 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
CD79A | WFS1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TERF1 | WFS1 | 21044950 24234451 25348397 | physical association | pull down,physical interaction,bimolecular fluorescence complementation | ComPPI,IntAct |
ADIPOR1 | WFS1 | 25348397 | N/A | physical interaction | ComPPI |
WFS1 | DRD2 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
F2RL1 | WFS1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
LTB4R2 | WFS1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |