Gene Information gene info

GENE:WFS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WFS1
FullNmae wolframin ER transmembrane glycoprotein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12762
EnsembleID ENSG00000109501
Uniprot O76024

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WFS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WFS1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WFS1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WFS1 GO:0000122,GO:0001822,GO:0003091,GO:0005515,GO:0005516,GO:0005783,GO:0005783,GO:0005788,GO:0005789,GO:0005789,GO:0005789,GO:0006983,GO:0006983,GO:0007601,GO:0007605,GO:0017148,GO:0022417,GO:0030141,GO:0030425,GO:0030433,GO:0030433,GO:0030672,GO:0030968,GO:0031016,GO:0031398,GO:0031398,GO:0031625,GO:0032469,GO:0034976,GO:0042048,GO:0042593,GO:0043066,GO:0043069,GO:0043433,GO:0043524,GO:0045927,GO:0048306,GO:0050821,GO:0050821,GO:0050821,GO:0050821,GO:0050877,GO:0051117,GO:0051247,GO:0051928,GO:0055074,GO:0055074,GO:0070628,GO:0140297,GO:1902236,GO:1903573,GO:1903892,GO:1904294,GO:2000675

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WFS1 hsa:7466 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 WFS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 WFS1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C WFS1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 WFS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
XBP1 WFS1 16539657 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D WFS1 \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000009262D WFS1 18927107 19253296 19342589 25416803 mrna cleavage,inhibition experimental interaction detection miR2Disease,TarBase

Source Target Pmid Interactiontype Methods Database
YIPF3 WFS1 25348397 N/A physical interaction ComPPI
ITGB3BP WFS1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSMA5 WFS1 25348397 N/A physical interaction ComPPI
CFTR WFS1 17110338 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAPK6 WFS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF6 WFS1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SYVN1 WFS1 25348397 N/A physical interaction ComPPI
ATF6 WFS1 25348397 N/A physical interaction ComPPI
ANTXR1 WFS1 25348397 N/A physical interaction ComPPI
SMURF1 WFS1 21454619 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CD79A WFS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TERF1 WFS1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ADIPOR1 WFS1 25348397 N/A physical interaction ComPPI
WFS1 DRD2 24234451 28298427 physical association ubiquitin reconstruction IntAct
F2RL1 WFS1 24234451 28298427 physical association ubiquitin reconstruction IntAct
LTB4R2 WFS1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization