Gene Information gene info

GENE:ZNF622

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZNF622
FullNmae zinc finger protein 622
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30958
EnsembleID ENSG00000173545
Uniprot Q969S3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZNF622 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZNF622 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZNF622 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ZNF622 GO:0003723,GO:0005515,GO:0005654,GO:0005730,GO:0005794,GO:0005829,GO:0008270,GO:0008631,GO:0030687,GO:0033674,GO:0042273,GO:0042273,GO:0043065,GO:0043410,GO:0046330,GO:1990275

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
OAS3 ZNF622 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP ZNF622 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR ZNF622 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ZNF622 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZNF622 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ZNF622 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ZNF622 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000475586 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 ZNF622 20371350 21572407 22473208 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C ZNF622 20371350 21572407 22473208 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D ZNF622 20371350 21572407 22473208 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A ZNF622 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 ZNF622 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 ZNF622 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAP3K5 ZNF622 22135298 phosphorylation N/A PhosphoSite
MYBL2 ZNF622 25361965 interaction type N/A PTMCode2
ZNF622 MYBL2 25361965 interaction type N/A PTMCode2
MELK ZNF622 25361965 interaction type N/A PTMCode2
ZNF622 MELK 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NPM1 ZNF622 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LCA5 ZNF622 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP1R2B ZNF622 25348397 N/A physical interaction ComPPI
ERBB2 ZNF622 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL10 ZNF622 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAXIP1 ZNF622 25348397 N/A physical interaction ComPPI
MYBL2 ZNF622 12645566 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
MAP3K5 ZNF622 21771788 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,pull down,in-gel kinase assay,comigration in gel electrophoresis ComPPI,IntAct
HNRNPU ZNF622 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTN1 ZNF622 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EIF6 ZNF622 25348397 N/A physical interaction ComPPI
MELK ZNF622 11802789 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
HIF1AN ZNF622 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
HECTD1 ZNF622 25348397 N/A physical interaction ComPPI
YAF2 ZNF622 25348397 N/A physical interaction ComPPI
CAVIN1 ZNF622 25348397 N/A physical interaction ComPPI
ZNF622 OAS3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZNF622 APP 25348397 N/A physical interaction ComPPI
ZNF622 WDR33 25348397 N/A physical interaction ComPPI
ZNF622 EFTUD2 25348397 N/A physical interaction ComPPI
ZNF622 RBM28 25348397 N/A physical interaction ComPPI
ZNF622 GLA 25348397 N/A physical interaction ComPPI
ZNF622 UBFD1 25348397 N/A physical interaction ComPPI
ZNF622 G6PD 25348397 N/A physical interaction ComPPI
ZNF622 NPEPPS 25348397 N/A physical interaction ComPPI
ZNF622 PPP1R2 25348397 N/A physical interaction ComPPI
ZNF622 SCLY 25348397 N/A physical interaction ComPPI
ZNF622 FTSJ3 25348397 N/A physical interaction ComPPI
ZNF622 POP1 25348397 N/A physical interaction ComPPI
ZNF622 STAU1 25348397 N/A physical interaction ComPPI
ZNF622 DNAJC21 25348397 N/A physical interaction ComPPI
ZNF622 UFL1 25348397 N/A physical interaction ComPPI
ZNF622 LSG1 25348397 N/A physical interaction ComPPI
ZNF622 MMTAG2 25348397 N/A physical interaction ComPPI
ZNF622 NMD3 25348397 N/A physical interaction ComPPI
ZNF622 NOC3L 25348397 N/A physical interaction ComPPI
ZNF622 NEMF 25348397 N/A physical interaction ComPPI
ZNF622 BRIX1 25348397 N/A physical interaction ComPPI
ZNF622 KRR1 25348397 N/A physical interaction ComPPI
ZNF622 MRTO4 25348397 N/A physical interaction ComPPI
ZNF622 EIF2B4 25348397 N/A physical interaction ComPPI
ZNF622 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ZNF622 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ZNF622 CCDC102B 25348397 N/A physical interaction ComPPI
ZNF622 PRPF31 25348397 N/A physical interaction ComPPI
ZNF622 FOS 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ZNF622 MACROH2A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EBNA1BP2 ZNF622 25348397 N/A physical interaction ComPPI
HSCB ZNF622 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
ZNF622 ZNF622 11802789 14525934 N/A experimental interaction detection,two hybrid HPRD
MAP3K5 ZNF622 21771788 27898060 stimulant N/A OmniPath

Visualization