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GENE：SLC19A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC19A1
FullNmae solute carrier family 19 member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10937
EnsembleID ENSG00000173638
Uniprot P41440

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC19A1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLC19A1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC19A1 GO:0005542,GO:0005886,GO:0005886,GO:0005886,GO:0006855,GO:0007565,GO:0008514,GO:0008517,GO:0008517,GO:0008518,GO:0008518,GO:0008518,GO:0015297,GO:0015350,GO:0015711,GO:0015884,GO:0015884,GO:0016323,GO:0016323,GO:0016323,GO:0016324,GO:0016324,GO:0016324,GO:0031526,GO:0042910,GO:0046655,GO:0051958,GO:0061507,GO:0098656,GO:0098838,GO:0098838,GO:0140360,GO:0140361,GO:0150104,GO:0150104,GO:1904447

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC19A1 hsa:6573 path:hsa01523 Antifolate resistance - Homo sapiens (human)
SLC19A1 hsa:6573 path:hsa04977 Vitamin digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SLC19A1 SP1 15652157 23180781 physical association anti tag coimmunoprecipitation InnateDB
SLC19A1 SP3 15652157 23180781 physical association anti tag coimmunoprecipitation InnateDB
SLC19A1 CEBPB 15652157 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPB SLC19A1 15652157 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
ESR1 SLC19A1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SLC19A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SLC19A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 SLC19A1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SLC19A1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC SLC19A1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 SLC19A1 15652157 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SMARCA4 SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SLC19A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 SLC19A1 11078737 trascriptional regulation,stimulation inferred by curator TFlink
JUN SLC19A1 11078737 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 SLC19A1 15652157 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SLC19A1 12228234 trascriptional regulation,stimulation inferred by curator TFlink
USF1 SLC19A1 15214842 trascriptional regulation,stimulation inferred by curator TFlink
USF2 SLC19A1 15214842 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 SLC19A1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 SLC19A1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE SLC19A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 SLC19A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065FDF SLC19A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD SLC19A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA SLC19A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SLC19A1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPL SLC19A1 25348397 N/A physical interaction ComPPI
TMEM216 SLC19A1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LAMP1 SLC19A1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CD164L2 SLC19A1 25348397 N/A physical interaction ComPPI
SLC19A1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct

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