GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
WDR35
FullNmae
WD repeat domain 35
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:29250
EnsembleID
ENSG00000118965
Uniprot
Q9P2L0
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
WDR35
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
WDR35
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
WDR35
GO:0005515,GO:0005813,GO:0005929,GO:0005929,GO:0005930,GO:0005930,GO:0030991,GO:0030991,GO:0030991,GO:0035721,GO:0035721,GO:0035721,GO:0036064,GO:0042073,GO:0060271,GO:0060271,GO:0060271,GO:0061512,GO:0097542,GO:1990830
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
AR
WDR35
20610535
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
E2F4
WDR35
17531812
18971253
trascriptional regulation,stimulation
chromatin immunoprecipitation array,inferred by curator
TFlink
ESR1
WDR35
18414489
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
ETS1
WDR35
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
YBX1
WDR35
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
FOXP3
WDR35
20554955
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
SMARCA4
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
GATA2
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TAL1
WDR35
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00003A5E54
WDR35
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS000015F70F
WDR35
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000007FBA
WDR35
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000003E1A9
WDR35
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000052EA98
WDR35
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
CUL3
WDR35
25348397
N/A
physical interaction
ComPPI
NTRK1
WDR35
25348397
N/A
physical interaction
ComPPI
DNAJC7
WDR35
25348397
N/A
physical interaction
ComPPI
PCNT
WDR35
25348397
N/A
physical interaction
ComPPI
AURKA
WDR35
25348397
N/A
physical interaction
ComPPI
MAD2L1
WDR35
25348397
N/A
physical interaction
ComPPI
NUDC
WDR35
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
ALYREF
WDR35
25348397
N/A
physical interaction
ComPPI
RNPS1
WDR35
25348397
N/A
physical interaction
ComPPI
NEK7
WDR35
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
IFT140
WDR35
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
KIF2A
WDR35
25348397
N/A
physical interaction
ComPPI
BCL6
WDR35
16147992
24234451
25348397
association
anti bait coimmunoprecipitation,physical interaction
ComPPI,IntAct
WDR35
IFT122
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
WDR35
TULP3
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
WDR35
WDR19
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
Visualization