GENE:MAP3K7
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MAP3K7 |
FullNmae | mitogen-activated protein kinase kinase kinase 7 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:6859 |
EnsembleID | ENSG00000135341 |
Uniprot | O43318 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MAP3K7 | necroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAP3K7 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAP3K7 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAP3K7 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
MAP3K7 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAP3K7 | anoikis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MAP3K7 | GO:0000165,GO:0000287,GO:0001223,GO:0001666,GO:0002223,GO:0002726,GO:0002753,GO:0002755,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004707,GO:0004709,GO:0004709,GO:0004709,GO:0005114,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0006338,GO:0006954,GO:0006955,GO:0007179,GO:0007249,GO:0007249,GO:0007250,GO:0007252,GO:0007254,GO:0007254,GO:0007254,GO:0008349,GO:0010008,GO:0010629,GO:0016239,GO:0030971,GO:0031625,GO:0032743,GO:0034138,GO:0034142,GO:0035173,GO:0035666,GO:0038066,GO:0038066,GO:0038095,GO:0038172,GO:0038173,GO:0042742,GO:0042802,GO:0043123,GO:0043123,GO:0043123,GO:0043276,GO:0043507,GO:0043507,GO:0043966,GO:0045787,GO:0045793,GO:0050852,GO:0050852,GO:0051403,GO:0070423,GO:0070498,GO:0071356,GO:0090650,GO:0097110,GO:0106310,GO:0120283,GO:0140297,GO:0140672,GO:1904385,GO:1904707,GO:1904754,GO:1990450 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
MAP3K7 | hsa:6885 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04064 | NF-kappa B signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04140 | Autophagy - animal - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04152 | AMPK signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04520 | Adherens junction - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04613 | Neutrophil extracellular trap formation - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04620 | Toll-like receptor signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04622 | RIG-I-like receptor signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04657 | IL-17 signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04660 | T cell receptor signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04668 | TNF signaling pathway - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa04936 | Alcoholic liver disease - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05131 | Shigellosis - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05132 | Salmonella infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05135 | Yersinia infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05140 | Leishmaniasis - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05145 | Toxoplasmosis - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05162 | Measles - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05168 | Herpes simplex virus 1 infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
MAP3K7 | hsa:6885 | path:hsa05418 | Fluid shear stress and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
MAP3K7 | TAB3 | 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 21903422 22941947 23180781 23681101 24403530 24699077 24958845 26192618 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
TAB2 | MAP3K7 | 10391247 11259596 11280761 11460167 11477091 12242293 12620219 14633987 14660645 14670075 15082531 15125833 16603398 16799562 17301840 17363905 18180283 18264787 18641653 18988627 19026643 19161412 19955178 20164171 21041997 21071413 21133840 21232017 21903422 22941947 23180781 23331499 23681101 24403530 24699077 24958845 26192618 | interaction type,stimulation,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB,SignaLink,SignaLink |
MAP3K7 | MAP2K4 | 10391247 11280761 11460167 11477091 12620219 13130464 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23109003 23681101 24403530 24699077 24958845 26192618 8177321 9851932 | interaction type,chemical activation reaction | N/A | ACSN,SignaLink |
MAP3K7 | IKBKG | 10391247 10702308 11280761 11325957 11460167 11477091 12620219 14514672 14633987 14660645 15082531 15125833 15327770 16301747 16356855 16603398 16799562 17047224 17301840 17363905 17496917 18079694 18223652 18264787 18641653 19161412 19909372 20164171 20300203 21041997 21133840 21232017 22941947 23109003 23681101 24403530 24699077 24958845 26192618 29145629 9744859 | interaction type,enzymatic reaction,physical association,chemical activation reaction | inferred by curator | ACSN,Reactome,SignaLink |
MAP3K7 | FOXP3 | 10391247 11280761 11460167 12620219 14633987 14660645 15082531 15125833 15282297 16200688 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20060931 20164171 21041997 21133840 21232017 22941947 24403530 24699077 24958845 26192618 | interaction type | N/A | ACSN |
MAP3K7 | MAP2K3 | 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23331499 23681101 24403530 24699077 24958845 26192618 8663074 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
MAP3K7 | MAP2K6 | 10391247 11280761 11460167 12620219 14633987 14660645 15082531 15125833 15282297 16200688 16603398 16799562 17301840 17363905 18264787 18641653 18988627 19161412 20060931 20164171 21041997 21133840 21232017 22941947 23331499 24403530 24699077 24958845 26192618 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
FYB1 | MAP3K7 | 20164171 26192618 | interaction type | N/A | ACSN |
TRAF6 | MAP3K7 | 10882101 10921914 11259596 11274345 11809792 12150927 12609980 12620219 14633987 14660645 15125833 16252010 16517750 17948050 18264787 18758450 18922473 19161412 19232515 23180781 26192618 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
PRKCQ | MAP3K7 | 10652356 15214048 15536066 16606694 17363905 17544292 17548359 18784374 19201850 20164171 23077238 23109003 23433459 23474202 23886063 25960930 26192618 | interaction type,chemical activation reaction | N/A | ACSN,SignaLink |
DUSP14 | MAP3K7 | 24403530 26192618 | interaction type | N/A | ACSN |
FADD | MAP3K7 | 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 | interaction type | N/A | ACSN |
RIPK1 | MAP3K7 | 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18570872 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
TNF | MAP3K7 | 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 | interaction type | N/A | ACSN |
TRADD | MAP3K7 | 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 | interaction type | N/A | ACSN |
TRAF2 | MAP3K7 | 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14633987 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17384642 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
MAP3K7 | TAB1 | 21903422 23180781 26192618 | association,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
ECSIT | MAP3K7 | 10465784 23180781 25371197 26192618 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
XIAP | MAP3K7 | 11865055 12048196 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
STRADB | MAP3K7 | 12048196 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TAB3 | MAP3K7 | 14633987 14670075 17158449 17384642 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PELI2 | MAP3K7 | 12804775 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PELI1 | MAP3K7 | 12804775 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | MAP3K5 | 10921914 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
SOCS3 | MAP3K7 | 16543409 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
HRAS | MAP3K7 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | PELI2 | 16831874 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | BCL10 | 10702308 10838074 10882101 11460167 14695475 15125833 15327770 16056267 16186825 16301747 16356855 16831874 17158449 17189706 17496917 19909372 20038579 20449947 20538596 22069318 23180781 29145629 | physical association | anti tag coimmunoprecipitation,inferred by curator | InnateDB,Reactome |
MAP3K3 | MAP3K7 | 16260783 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
IKBKB | MAP3K7 | 10187861 10807933 11325957 11460167 14514672 16301747 16356855 17047224 17496917 19909372 20300203 23180781 29145629 9744859 | phosphorylation reaction,enzymatic reaction,physical association | anti tag coimmunoprecipitation,inferred by curator,in-gel kinase assay | InnateDB,Reactome |
MAP3K7 | MAP3K7 | 10702308 10882101 11460167 12609980 15327770 15590691 16115877 17299140 17496917 19675569 19935683 20038579 20538596 21902831 23180781 24243840 26467481 29145629 9278437 9480845 9890973 | interaction type,phosphorylation reaction,bind,physical association,up-regulates activity,down-regulates quantity by destabilization | inferred by curator,in-gel kinase assay | InnateDB,Reactome,Signor |
SMAD6 | MAP3K7 | 10748100 11737269 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | TRAF5 | 17384642 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
RBCK1 | MAP3K7 | 17449468 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TNFRSF11A | MAP3K7 | 11809792 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
HGS | MAP3K7 | 11397816 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP2K6 | MAP3K7 | 11460167 21220427 23180781 | phosphorylation reaction | in-gel kinase assay,protein kinase assay | InnateDB |
PPM1B | MAP3K7 | 11104763 23180781 | dephosphorylation reaction,physical association | anti tag coimmunoprecipitation,in gel phosphatase assay | InnateDB |
MAP4K1 | MAP3K7 | 10224067 23180781 23331499 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink |
MAPK8 | MAP3K7 | 11865055 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | TRAF3IP2 | 12089335 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NOD2 | MAP3K7 | 15075345 17348859 17965022 23180781 | physical association | anti tag coimmunoprecipitation,gst pull down | InnateDB |
RIPK2 | MAP3K7 | 17348859 17947236 17965022 18079694 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TAOK2 | MAP3K7 | 16893890 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TAOK1 | MAP3K7 | 16893890 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
JAZF1 | MAP3K7 | 15302198 15302918 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down | InnateDB |
SKIL | MAP3K7 | 17276978 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
TAB1 | MAP3K7 | 10094049 10702308 10838074 10921914 12429732 14670075 15590691 16845370 17348859 18180283 18988627 19026643 20200282 21071413 21903422 23180781 23331499 8638164 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink,SignaLink |
IRAK1 | MAP3K7 | 12242293 17197697 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | TAB2 | 10882101 12609980 14633987 14670075 15590691 16603398 17384642 18180283 20200282 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | TRAF6 | 14633987 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | TRAF2 | 14633987 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP4K4 | MAP3K7 | 10807933 23180781 23331499 9890973 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink |
PEBP1 | MAP3K7 | 11585904 23180781 23331499 | stimulation,physical association | anti tag coimmunoprecipitation | InnateDB,SignaLink |
SMAD7 | MAP3K7 | 12589052 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAVS | MAP3K7 | 16153868 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PTPN6 | MAP3K7 | 17079228 23180781 | dephosphorylation reaction,physical association | anti tag coimmunoprecipitation,dephosphorylation reaction | InnateDB |
TLR3 | MAP3K7 | 12609980 16115877 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
EIF2AK2 | MAP3K7 | 12609980 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TNFRSF1A | MAP3K7 | 16115877 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ELP1 | MAP3K7 | 10094049 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ERLIN1 | MAP3K7 | 16893890 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
FBXW5 | MAP3K7 | 19232515 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ROR2 | MAP3K7 | 18762249 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SIVA1 | MAP3K7 | 19584092 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
DYNC2I2 | MAP3K7 | 19521662 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
CHUK | MAP3K7 | 11325957 11460167 14514672 16301747 16356855 17047224 17496917 18949366 19909372 20300203 23180781 29145629 9744859 | enzymatic reaction,physical association | affinity chromatography technology,inferred by curator | InnateDB,Reactome |
MAP3K7 | TIPRL | 20200282 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IL17RA | MAP3K7 | 17277779 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TRAF3IP2 | MAP3K7 | 17277779 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
YWHAE | MAP3K7 | 20462248 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
EGR1 | MAP3K7 | 19032775 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | DAAM1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IKBKG | MAP3K7 | 18180283 23180781 | physical association | pull down | InnateDB |
SASH1 | MAP3K7 | 23180781 23776175 | physical association | anti tag coimmunoprecipitation | InnateDB |
PRKX | MAP3K7 | 23180781 25028512 | physical association | anti tag coimmunoprecipitation | InnateDB |
PRKACA | MAP3K7 | 23180781 25028512 | physical association | anti tag coimmunoprecipitation | InnateDB |
MAP3K7 | UBB | 23180781 24816145 | physical association | deubiquitinase assay | InnateDB |
MAP3K7 | MALT1 | 10702308 10838074 10882101 11460167 14695475 15125833 15327770 16056267 16186825 16301747 16356855 17158449 17496917 19909372 20038579 20449947 20538596 22069318 29145629 | physical association | inferred by curator | Reactome |
MAP3K7 | CARD11 | 10702308 10838074 10882101 11460167 14695475 15125833 15327770 16056267 16186825 16301747 16356855 17158449 17496917 19909372 20449947 29145629 | physical association | inferred by curator | Reactome |
MAP3K7 | USP18 | 23825189 24243840 29145629 | physical association | inferred by curator | Reactome |
MAP3K7 | MAP2K7 | 23331499 9890973 | stimulation | N/A | SignaLink,SignaLink |
MAP3K7 | NLK | 10391247 23331499 | stimulation | N/A | SignaLink |
TGFBR2 | MAP3K7 | 16360132 23331499 | stimulation | N/A | SignaLink |
MAP3K7 | MAP2K2 | 13130464 23109003 8177321 9851932 | chemical activation reaction | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
BCL10 | MAP3K7 | 20005715 | interaction type | N/A | PSP |
HGS | MAP3K7 | 20005715 | interaction type | N/A | PSP |
TAB2 | MAP3K7 | 20005715 | interaction type | N/A | PSP |
MAPK8IP1 | MAP3K7 | 20005715 | interaction type | N/A | PSP |
MAVS | MAP3K7 | 20005715 | interaction type | N/A | PSP,SignaLink |
TRAF2 | MAP3K7 | 14633987 20005715 21071413 | interaction type | N/A | PSP,SignaLink |
TRAF3IP2 | MAP3K7 | 20005715 | interaction type | N/A | PSP,SignaLink |
HGS | MAP3K7 | 11397816 18988627 20005715 21071413 | N/A | N/A | SignaLink |
TAB2 | MAP3K7 | 20005715 20005715 | N/A | N/A | SignaLink |
MAPK8IP1 | MAP3K7 | 18286207 18988627 20005715 20005715 | N/A | N/A | SignaLink |
BCL10 | MAP3K7 | 20005715 20005715 | N/A | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | MAP3K7 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | MAP3K7 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
ETS1 | MAP3K7 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | MAP3K7 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | MAP3K7 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | MAP3K7 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | MAP3K7 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | MAP3K7 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | MAP3K7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000016D2D4 | MAP3K7 | 20624982 | rna interference,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS000016D2D4 | MAP3K7 | 20624982 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00000EED18 | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00002971AB | MAP3K7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000008A99 | MAP3K7 | 22942087 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000023133F | MAP3K7 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075AEA5 | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008F0CF | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002E1509 | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002198F3 | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027352D | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000366551 | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041FA2C | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F2EB0 | MAP3K7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000475586 | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F6E49 | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007D64A | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F0F49 | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040EE1D | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041CB9C | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000171CD1 | MAP3K7 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000237AF9 | MAP3K7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040EC3B | MAP3K7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000042B108 | MAP3K7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B0D1E | MAP3K7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000277201 | MAP3K7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
MAP3K7 | POLD2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | HDAC7 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | HDAC4 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | TUBA1B | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | PTPN3 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | MAP2K6 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | EIF4B | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | HNRNPA2B1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | TUBB | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | KSR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | TAB1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | FLNA | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | RBMX | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | MAP3K7 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | GAPVD1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | PRKAA2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | E2F1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | HSP90B1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | HDAC5 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | RAB1A | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | EEF1A1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAP3K7 | LDHA | 22135298 | phosphorylation | N/A | PhosphoSite |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NUDT21 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
SOCS3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
HSPA8 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
SGF29 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
ROR2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
HSPBP1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
SKIL | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
PSMC3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
ACTG1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
POLE4 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
PPP2R1A | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
DYNC2I2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TUBB | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
NRIP1 | MAP3K7 | 14525934 25348397 9556573 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
TRAF6 | MAP3K7 | 10094049 12496252 14525934 18758450 19820695 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
CALM1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
XIAP | MAP3K7 | 12048196 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
DR1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MCM2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TAB3 | MAP3K7 | 21903422 22081109 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
HSP90AB1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
GPR25 | MAP3K7 | 14525934 18286207 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
RACK1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
NLK | MAP3K7 | 15764709 24234451 25241761 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,proximity ligation assay | ComPPI,IntAct |
EGLN3 | MAP3K7 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
H4C1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
SYK | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
PRKCQ | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
EZH2 | MAP3K7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
TGFBR2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAPK8 | MAP3K7 | 11865055 14525934 17709393 24234451 25348397 | physical association | experimental interaction detection,molecular sieving,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
SMAD7 | MAP3K7 | 12589052 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MAP4K1 | MAP3K7 | 10224067 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
HCFC1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
SMAD3 | MAP3K7 | 14525934 24234451 25241761 25348397 9380693 | physical association | experimental interaction detection,physical interaction,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
COPS5 | MAP3K7 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
MAPK14 | MAP3K7 | 12589052 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
FLNA | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
DAAM1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
RBX1 | MAP3K7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
SLC9A1 | MAP3K7 | 20936779 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
MAP4K4 | MAP3K7 | 25348397 | N/A | in vitro,in vivo | ComPPI |
HGS | MAP3K7 | 11397816 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
PRKAA1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
UBC | MAP3K7 | 16845370 19820695 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
HSP90AA1 | MAP3K7 | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification,tandem affinity purification | ComPPI |
ENO1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
RUVBL1 | MAP3K7 | 24234451 25241761 25348397 | physical association | physical interaction,tandem affinity purification,proximity ligation assay | ComPPI,IntAct |
EIF2AK2 | MAP3K7 | 12609980 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
PDPK1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAP2K4 | MAP3K7 | 12556533 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
HSPA5 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K5 | MAP3K7 | 10921914 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
IKBKB | MAP3K7 | 10022904 10195894 10779355 11460167 14525934 17363973 24234451 25348397 9689078 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct |
TIRAP | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MYC | MAP3K7 | 21150319 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
TRAF3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
PEBP1 | MAP3K7 | 11585904 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
TNFRSF1A | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
NFKBIA | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
CAD | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
DDX5 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAPK6 | MAP3K7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
PPP2CA | MAP3K7 | 17079228 24234451 25348397 | dephosphorylation reaction | phosphatase assay | ComPPI,IntAct |
IRAK1 | MAP3K7 | 12242293 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
TNF | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
RELA | MAP3K7 | 14525934 16498455 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
MAPK8IP1 | MAP3K7 | 14525934 16840345 17709393 18286207 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro | ComPPI,HPRD,IntAct |
ERC1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TNIK | MAP3K7 | 22904686 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
EPRS1 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
ATM | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
XPO1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
USP4 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TRAF2 | MAP3K7 | 25348397 | N/A | physical interaction,tandem affinity purification | ComPPI |
TADA3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
PRMT2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
CLTC | MAP3K7 | 24234451 25241761 25348397 | physical association | physical interaction,tandem affinity purification,proximity ligation assay | ComPPI,IntAct |
ARRB2 | MAP3K7 | 17620599 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRAF5 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
SIVA1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
YWHAE | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
FYB1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAP2K6 | MAP3K7 | 11460167 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
THBS3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
CNTN2 | MAP3K7 | 17363973 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
HIPK2 | MAP3K7 | 14525934 15082531 23565059 24234451 25348397 | association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct |
HSPB1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
KAT2A | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
ITCH | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TAOK2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
RNF19A | MAP3K7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
CHUK | MAP3K7 | 10094049 10187861 14525934 24234451 25241761 25348397 | association,physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
HSPA9 | MAP3K7 | 25348397 | N/A | tandem affinity purification | ComPPI |
RIPK1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
RIPK2 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
TRAIP | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K14 | MAP3K7 | 10094049 14525934 25348397 | N/A | coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
TH | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
HIF1AN | MAP3K7 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
TRAF4 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAGED1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | SMAD6 | 10748100 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MAP3K7 | TNFRSF11A | 11809792 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MAP3K7 | ELP1 | 10094049 14525934 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct |
MAP3K7 | PPM1B | 11104763 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAP3K7 | TRAF3IP2 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
MAP3K7 | NAIP | 11865055 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAP3K7 | PELI3 | 12874243 14525934 25348397 | N/A | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAP3K7 | PPM1L | 12556533 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAP3K7 | STRADB | 12048196 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MAP3K7 | IL17RD | 25348397 | N/A | physical interaction,in vivo | ComPPI |
MAP3K7 | TAB2 | 11259596 14525934 16845370 17158449 18180283 21903422 22081109 22158122 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,two hybrid | ComPPI,HPRD,IntAct |
MAP3K7 | CARD11 | 14525934 16301747 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
MAP3K7 | MAVS | 14525934 16153868 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAP3K7 | STAT3 | 14525934 15764709 24234451 25348397 3031469 | association,physical association | anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo | ComPPI,HPRD,IntAct |
MAP3K7 | MAP3K3 | 14525934 16260783 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
MAP3K7 | VRK2 | 14525934 17709393 18286207 24234451 25348397 | physical association | experimental interaction detection,pull down,physical interaction,in vitro | ComPPI,HPRD,IntAct |
MAP3K7 | TAB1 | 10838074 14525934 16845370 18180283 22158122 24234451 25241761 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,tandem affinity purification,proximity ligation assay | ComPPI,HPRD,IntAct |
MAP3K7 | TGFBR1 | 14525934 18758450 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
MAP3K7 | CYLD | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | IKBKG | 17363973 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MAP3K7 | MIB2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | PPP6C | 17079228 24234451 25348397 | dephosphorylation reaction,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,phosphatase assay | ComPPI,IntAct |
MAP3K7 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | CDC37 | 25348397 | N/A | physical interaction,physical interaction,tandem affinity purification,tandem affinity purification | ComPPI |
MAP3K7 | BBS10 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MAP3K7 | PPP5C | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MAP3K7 | ZNF746 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MAP3K7 | NDUFS6 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MAP3K7 | TLR3 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | RBCK1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | TRIM8 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | EDARADD | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | YEATS2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | FBXW5 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | TRIM5 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | DAZAP2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | PRKAB1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | NOD2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | IL17RA | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | TAOK1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | PINK1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | BST2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | USP2 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | MALT1 | 17948050 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MAP3K7 | SASH1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | SIK1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | STUB1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | ECSIT | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | CARD8 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | CARNMT1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | NDFIP1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | MED4 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | RBM7 | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
MAP3K7 | HSPA1L | 24234451 25241761 25348397 | physical association | physical interaction,tandem affinity purification,proximity ligation assay | ComPPI,IntAct |
MAP3K7 | MAP2K7 | 17110930 17709393 24234451 25241761 25348397 | physical association | anti tag coimmunoprecipitation,molecular sieving,physical interaction,proximity ligation assay | ComPPI,IntAct |
MAP3K7 | RNF4 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | USP18 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | FBXL17 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | CRBN | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | EMILIN1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | SYNC | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | AARSD1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | PCDH20 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | CCDC102B | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | TBL1Y | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | SCRN1 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | KERA | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | IL17RC | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | THBS4 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | IFIT5 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | FKBP5 | 25348397 | N/A | physical interaction,tandem affinity purification,tandem affinity purification | ComPPI |
MAP3K7 | RUVBL2 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | RPS3 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | DNAJA1 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | IARS1 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | TUBB2B | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | TUBB4A | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | RPLP0P6 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | DARS1 | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | TUBA3C | 25348397 | N/A | tandem affinity purification | ComPPI |
MAP3K7 | AKTIP | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
MAP3K7 | EZR | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
MAP3K7 | TOMM20 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
BCL10 | MAP3K7 | 14525934 16186825 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
MUL1 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
ZNF593 | MAP3K7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
SIK3 | MAP3K7 | 25348397 | N/A | physical interaction | ComPPI |
MAP3K7 | MAP3K7 | 10838074 11259596 14525934 18758450 9556573 | N/A | experimental interaction detection,two hybrid | HPRD |
MAP3K7 | FOS | 11397816 14525934 | N/A | experimental interaction detection | HPRD |
SHARPIN | MAP3K7 | 24234451 30561431 | association | virotrap | IntAct |
MAP3K7 | JAZF1 | 15302198 15302918 27898060 | N/A | N/A | OmniPath |
MAP3K7 | PRKAA2 | 15465812 21228273 23716691 25937278 26001218 27898060 | stimulant | N/A | OmniPath |
PRKACA | MAP3K7 | 25028512 27898060 | N/A | N/A | OmniPath |
CAMK2B | MAP3K7 | 12482967 27898060 | N/A | N/A | OmniPath |
SOCS3 | MAP3K7 | 16543409 27898060 | N/A | N/A | OmniPath |
MAP3K7 | SOCS3 | 16543409 27898060 | N/A | N/A | OmniPath |
TGFBR2 | MAP3K7 | 16360132 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | NOD2 | 15075345 17348859 17965022 27898060 | N/A | N/A | OmniPath |
NOD2 | MAP3K7 | 10702308 15075345 17079228 17348859 17947236 17965022 27898060 | N/A | N/A | OmniPath |
CHUK | MAP3K7 | 10094049 10187861 16893890 18949366 20200282 25241761 27898060 9742107 | N/A | N/A | OmniPath |
MAP3K7 | CHUK | 10094049 10187861 15836773 16893890 18949366 20200282 25241761 27898060 9742107 | stimulant | N/A | OmniPath |
TRAF2 | MAP3K7 | 14633987 17384642 20038579 26299341 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | RIPK2 | 10702308 15075345 17079228 17348859 17947236 17965022 18079694 27898060 | N/A | N/A | OmniPath |
RIPK2 | MAP3K7 | 10702308 15075345 17079228 17348859 17947236 17965022 18079694 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | EIF2AK2 | 12609980 27898060 | N/A | N/A | OmniPath |
MAP3K7 | HRAS | 11744690 27898060 | N/A | N/A | OmniPath |
MAP3K7 | TIPRL | 20200282 27898060 | N/A | N/A | OmniPath |
MAP3K7 | MAP3K14 | 10094049 10807933 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | BCL10 | 16186825 16831874 17189706 22411628 27898060 | N/A | N/A | OmniPath |
BCL10 | MAP3K7 | 16186825 16831874 17189706 22411628 27898060 | N/A | N/A | OmniPath |
TRAF6 | MAP3K7 | 10094049 10702308 10882101 10921914 11259596 11809792 12242293 12496252 12609980 14633987 16410796 16517750 16543409 17079228 17145710 17947236 17965022 18635759 18758450 19112497 19232515 19521662 19675569 19820695 19843958 19898473 21245467 21822258 22637723 22643835 22649194 22851693 22924441 23960234 24434549 24558484 25828701 25963657 26038599 26474655 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | SIVA1 | 19584092 27898060 | N/A | N/A | OmniPath |
MAP3K7 | NFKB1 | 27898060 9480845 | stimulant | N/A | OmniPath |
MAP3K7 | MAVS | 16153868 27898060 | N/A | N/A | OmniPath |
MAP3K7 | PEBP1 | 11585904 27898060 | N/A | N/A | OmniPath |
PEBP1 | MAP3K7 | 11585904 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | XIAP | 11865055 12048196 19584092 27898060 | N/A | N/A | OmniPath |
XIAP | MAP3K7 | 11865055 12048196 19584092 27898060 | N/A | N/A | OmniPath |
MAP3K7 | MAP2K4 | 12429732 12556533 27898060 9278437 | stimulant | N/A | OmniPath |
MAP3K7 | MAP3K5 | 10921914 22167179 27898060 | N/A | N/A | OmniPath |
MAP3K5 | MAP3K7 | 10921914 22167179 27898060 | N/A | N/A | OmniPath |
MAP3K7 | IKBKG | 15836773 17363973 18180283 19531477 19898473 20038579 21566132 21606198 23986494 27898060 | inhibition,stimulant | N/A | OmniPath |
IKBKG | MAP3K7 | 17363973 18180283 19531477 19898473 20038579 21566132 21606198 23986494 27898060 | N/A | N/A | OmniPath |
PTPN6 | MAP3K7 | 17079228 27898060 | N/A | N/A | OmniPath |
MAP3K7 | MAP2K3 | 12791976 17299140 21902831 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | MAPK14 | 12589052 15692051 17947236 17965022 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | NFKBIA | 10195894 11087742 12514169 16493424 17965022 27898060 7739562 7796813 7862124 7878466 8657102 9480845 | inhibition | N/A | OmniPath |
MAP3K7 | HDAC4 | 10869435 10958686 24904057 27898060 | N/A | N/A | OmniPath |
MAP3K7 | TAB2 | 10838074 10882101 11259596 11460167 12242293 12372426 12609980 14633987 14670075 14743216 15590691 16603398 16845370 17158449 17384642 18021073 18180283 19026643 19232515 19556242 19675569 19843958 19955178 20194509 20200282 20538596 21903422 22081109 22158122 22167179 24061540 24912525 25642820 26432169 27898060 8638164 | inhibition | N/A | OmniPath |
TAB2 | MAP3K7 | 10838074 10882101 11259596 11460167 12242293 12372426 12609980 14633987 14670075 14743216 15590691 16251197 16603398 16845370 17158449 17384642 18021073 18180283 19026643 19232515 19556242 19675569 19843958 19955178 20194509 20200282 20538596 20932475 21903422 22081109 22158122 22167179 24061540 24912525 25642820 26432169 27898060 8638164 | stimulant | N/A | OmniPath |
MAP3K7 | MAP2K6 | 10094049 10702308 10838074 11460167 12242293 12556533 12609980 14633987 15590691 15764709 16893890 17079228 17363905 17363973 17384642 19675569 20932476 21220427 21902831 23606331 26038599 27898060 | stimulant | N/A | OmniPath |
MAP2K6 | MAP3K7 | 10094049 10702308 10838074 11460167 12242293 12556533 12609980 14633987 15590691 15764709 16893890 17079228 17363905 17363973 17384642 19675569 20932476 21220427 23606331 26038599 27898060 | N/A | N/A | OmniPath |
MAP3K7 | MAP3K4 | 27898060 9890973 | stimulant | N/A | OmniPath |
PPP2CA | MAP3K7 | 17079228 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | HIPK2 | 15082531 27898060 | stimulant | N/A | OmniPath |
RIPK1 | MAP3K7 | 16543241 18570872 21606198 24434549 27898060 | stimulant | N/A | OmniPath |
TNFRSF1A | MAP3K7 | 16115877 16260783 18037881 18949366 21331078 27898060 | stimulant | N/A | OmniPath |
TLR3 | MAP3K7 | 12609980 16115877 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | PARP1 | 15302918 27898060 | N/A | N/A | OmniPath |
UBE2N | MAP3K7 | 10702308 17079228 17965022 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | ROR2 | 18762249 27898060 | N/A | N/A | OmniPath |
ROR2 | MAP3K7 | 18762249 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | NFKBIB | 27898060 9480845 | inhibition | N/A | OmniPath |
MAP3K7 | MAP2K7 | 17110930 25241761 27898060 9890973 | stimulant | N/A | OmniPath |
MAP3K7 | NLK | 10377264 10391247 10823839 11071635 11404460 12482967 12709429 15082531 15640443 20194509 25241761 27898060 7693453 | stimulant | N/A | OmniPath |
MAP3K7 | MAP3K3 | 16260783 19843958 27898060 | N/A | N/A | OmniPath |
MAP3K7 | TAB1 | 10702308 10838074 10882101 10921914 11259596 11460167 12242293 12372426 12429732 12975377 14633987 14670075 14743216 15590691 16260783 16289117 16845370 17145710 17299140 17348859 17560374 18180283 18456659 19026643 19232515 19556242 19775907 20200282 20538596 21903422 22158122 22167179 22216226 23934659 24912525 25241761 26432169 27898060 8638164 | stimulant | N/A | OmniPath |
TAB1 | MAP3K7 | 10702308 10838074 10882101 10921914 11259596 11460167 12242293 12372426 12429732 12975377 14633987 14670075 14743216 15590691 16260783 16289117 16845370 17145710 17299140 17348859 17560374 18180283 18456659 19026643 19232515 19556242 19775907 20200282 20538596 21903422 22158122 22167179 23934659 24912525 25241761 26432169 27898060 8638164 | stimulant | N/A | OmniPath |
MAP3K7 | MAPK8 | 11865055 15692051 17186025 17947236 17965022 27898060 | stimulant | N/A | OmniPath |
MAPK8 | MAP3K7 | 11865055 27898060 | N/A | N/A | OmniPath |
MAP3K7 | IRAK1 | 12242293 17197697 19026643 23244239 27898060 | N/A | N/A | OmniPath |
MAP3K7 | IKBKB | 10022904 10094049 10187861 10195894 10779355 10807933 10837071 11129660 11460167 12547194 14530355 15214841 15327770 15502405 15620648 15691841 15836773 16006187 16186825 16260493 16493424 17363905 17363973 17965022 18316610 18456659 19632174 20932476 21331078 24270572 25946971 27898060 9689078 | stimulant | N/A | OmniPath |
YWHAE | MAP3K7 | 20462248 27898060 | N/A | N/A | OmniPath |
MAP3K7 | PELI2 | 12804775 16831874 27898060 | N/A | N/A | OmniPath |
ELP1 | MAP3K7 | 10094049 27898060 | N/A | N/A | OmniPath |
MAP3K7 | DAAM1 | 21903422 27898060 | N/A | N/A | OmniPath |
MAP3K7 | TAOK2 | 16893890 27898060 | N/A | N/A | OmniPath |
TAOK2 | MAP3K7 | 16893890 27898060 | N/A | N/A | OmniPath |
MAP3K7 | KSR1 | 11741534 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | TNFRSF11A | 11809792 27898060 | N/A | N/A | OmniPath |
TNFRSF11A | MAP3K7 | 11809792 27898060 | N/A | N/A | OmniPath |
MAP3K7 | FBXW5 | 19232515 27898060 | N/A | N/A | OmniPath |
MAP3K7 | DYNC2I2 | 19521662 27898060 | N/A | N/A | OmniPath |
DYNC2I2 | MAP3K7 | 19521662 27898060 | N/A | N/A | OmniPath |
SMAD7 | MAP3K7 | 12589052 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | SMAD7 | 12589052 27898060 | N/A | N/A | OmniPath |
ERLIN1 | MAP3K7 | 16893890 27898060 | N/A | N/A | OmniPath |
MAP3K7 | SKIL | 17276978 27898060 | N/A | N/A | OmniPath |
SKIL | MAP3K7 | 17276978 27898060 | N/A | N/A | OmniPath |
GTPBP2 | MAP3K7 | 17277779 27898060 | N/A | N/A | OmniPath |
TAOK1 | MAP3K7 | 16893890 27898060 | N/A | N/A | OmniPath |
MAP3K7 | PPM1B | 11104763 27898060 | N/A | N/A | OmniPath |
PPM1B | MAP3K7 | 11104763 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | TRAF5 | 17384642 27898060 | N/A | N/A | OmniPath |
MAP3K7 | HDAC5 | 11081517 18184930 18332134 18951085 20716686 21081666 21146494 22243750 23161540 23349925 24120667 24207022 24841198 25012661 26170313 27898060 | N/A | N/A | OmniPath |
MAP3K7 | SMAD6 | 10748100 11737269 27898060 | N/A | N/A | OmniPath |
SMAD6 | MAP3K7 | 10748100 11737269 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | STRADB | 12048196 27898060 | N/A | N/A | OmniPath |
MAP3K7 | PELI1 | 12804775 27898060 | N/A | N/A | OmniPath |
MAP3K7 | HGS | 11397816 27898060 | N/A | N/A | OmniPath |
SASH1 | MAP3K7 | 23776175 27898060 | N/A | N/A | OmniPath |
MAP3K7 | RBCK1 | 17449468 27898060 | N/A | N/A | OmniPath |
RBCK1 | MAP3K7 | 17449468 27898060 | N/A | N/A | OmniPath |
PRKX | MAP3K7 | 25028512 27898060 | N/A | N/A | OmniPath |
MAP3K7 | TAB3 | 14633987 14670075 17158449 17384642 18021073 19232515 19955178 21903422 22081109 24912525 27898060 | N/A | N/A | OmniPath |
TAB3 | MAP3K7 | 14633987 14670075 17158449 17384642 18021073 19232515 19955178 21903422 22081109 24912525 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | TRAF3IP2 | 12089335 17277779 27898060 | N/A | N/A | OmniPath |
TRAF3IP2 | MAP3K7 | 12089335 17277779 27898060 | N/A | N/A | OmniPath |
MAP3K7 | MAP4K4 | 10807933 27898060 9890973 | stimulant | N/A | OmniPath |
MAP4K4 | MAP3K7 | 10807933 27898060 9890973 | stimulant | N/A | OmniPath |
MAP3K7 | MAP4K1 | 10224067 27898060 | N/A | N/A | OmniPath |
MAP4K1 | MAP3K7 | 10224067 27898060 | stimulant | N/A | OmniPath |
MAP3K7 | HDAC7 | 16980613 27898060 | inhibition | N/A | OmniPath |
MAP3K7 | PTPN3 | 27898060 9341175 | N/A | N/A | OmniPath |
CAMK2G | MAP3K7 | 12482967 27898060 | stimulant | N/A | OmniPath |
PPP6C | MAP3K7 | 17079228 19955178 27898060 | inhibition | N/A | OmniPath |
PPP2CB | MAP3K7 | 17079228 27898060 | N/A | N/A | OmniPath |
PPM1L | MAP3K7 | 12556533 27898060 | N/A | N/A | OmniPath |
CAMK2D | MAP3K7 | 12482967 27898060 | N/A | N/A | OmniPath |