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GENE：MYBBP1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYBBP1A
FullNmae MYB binding protein 1a
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7546
EnsembleID ENSG00000132382
Uniprot Q9BQG0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYBBP1A apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYBBP1A apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MYBBP1A anoikis 23388179 In vivo and in vitro experiments using the breast cancer cell lines MCF-7 and ZR-75-1, which expresses wild type p53, showed that tumorigenesis, colony formation, and anoikis resistance were significantly enhanced by MYBBP1A knockdown. retulator signature

Go Annotation:

GeneSymbol Go id
MYBBP1A GO:0001649,GO:0003714,GO:0003714,GO:0003723,GO:0005634,GO:0005634,GO:0005654,GO:0005730,GO:0005730,GO:0005730,GO:0005730,GO:0005737,GO:0006338,GO:0006355,GO:0016020,GO:0022904,GO:0032922,GO:0035066,GO:0042149,GO:0042254,GO:0042564,GO:0043231,GO:0043565,GO:0045892,GO:0045943,GO:0045944,GO:0045945,GO:0070888,GO:0072332,GO:0110016,GO:1903450,GO:2000210

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED MYBBP1A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 MYBBP1A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 MYBBP1A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
APP MYBBP1A 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MYBBP1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MYBBP1A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF MYBBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYBBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYBBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYBBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MYBBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB MYBBP1A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 MYBBP1A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 MYBBP1A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002152A8 MYBBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 MYBBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC MYBBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB MYBBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004CFC54 MYBBP1A 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKA MYBBP1A 22135298 phosphorylation N/A PhosphoSite
CHEK1 MYBBP1A 22135298 phosphorylation N/A PhosphoSite
AURKB MYBBP1A 22135298 phosphorylation N/A PhosphoSite
MYB MYBBP1A 25361965 interaction type N/A PTMCode2
MYBBP1A MYB 25361965 interaction type N/A PTMCode2
PCNA MYBBP1A 25361965 interaction type N/A PTMCode2
MYBBP1A PCNA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXB9 MYBBP1A 25348397 N/A physical interaction ComPPI
UBE2I MYBBP1A 25348397 N/A physical interaction ComPPI
CDC5L MYBBP1A 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPC MYBBP1A 25348397 N/A physical interaction ComPPI
PPP1CC MYBBP1A 24234451 25348397 28330616 association pull down ComPPI,IntAct
NPM1 MYBBP1A 21297583 24234451 25348397 26496610 colocalization,association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
PCNA MYBBP1A 12171929 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
COIL MYBBP1A 19928837 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RPL37A MYBBP1A 25348397 N/A physical interaction ComPPI
LMNA MYBBP1A 25348397 N/A physical interaction ComPPI
MCM5 MYBBP1A 25348397 N/A physical interaction ComPPI
GABARAPL2 MYBBP1A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BMI1 MYBBP1A 25348397 N/A physical interaction ComPPI
KEAP1 MYBBP1A 25348397 N/A physical interaction ComPPI
NIFK MYBBP1A 25348397 N/A physical interaction ComPPI
SMN1 MYBBP1A 19928837 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
RRS1 MYBBP1A 25348397 N/A physical interaction ComPPI
RPL10 MYBBP1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FGF3 MYBBP1A 25348397 N/A physical interaction ComPPI
SND1 MYBBP1A 25348397 N/A physical interaction ComPPI
JUN MYBBP1A 14525934 24234451 25348397 25609649 8302594 association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
AR MYBBP1A 10607837 11779876 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
EP300 MYBBP1A 21471221 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A PPARGC1A 14525934 14744933 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
MYBBP1A DHX30 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MYBBP1A NR2E3 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MYBBP1A DDX56 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A MYC 17314511 17353931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MYBBP1A AIRE 25348397 N/A physical interaction ComPPI
MYBBP1A NR4A1 25348397 N/A physical interaction ComPPI
MYBBP1A BAZ1B 25348397 N/A physical interaction ComPPI
MYBBP1A VHL 25348397 N/A physical interaction ComPPI
MYBBP1A ELOC 25348397 N/A physical interaction ComPPI
MYBBP1A ELOB 25348397 N/A physical interaction ComPPI
MYBBP1A NOP2 25348397 N/A physical interaction ComPPI
MYBBP1A NCL 25348397 N/A physical interaction ComPPI
MYBBP1A RIOX2 25348397 N/A physical interaction ComPPI
MYBBP1A BOP1 25348397 N/A physical interaction ComPPI
MYBBP1A ZBTB7B 25348397 N/A physical interaction ComPPI
MYBBP1A NOP56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A MARK4 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A UBTF 21297583 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
MYBBP1A SIRT7 25348397 N/A physical interaction ComPPI
MYBBP1A SMARCA5 25348397 N/A physical interaction ComPPI
MYBBP1A HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MYBBP1A CUL3 25348397 N/A physical interaction ComPPI
MYBBP1A CUL1 25348397 N/A physical interaction ComPPI
MYBBP1A COPS5 25348397 N/A physical interaction ComPPI
MYBBP1A CAND1 25348397 N/A physical interaction ComPPI
MYBBP1A GRK5 25348397 N/A physical interaction ComPPI
MYBBP1A APP 25348397 N/A physical interaction ComPPI
MYBBP1A RPL7 25348397 N/A physical interaction ComPPI
MYBBP1A RPL4 25348397 N/A physical interaction ComPPI
MYBBP1A RPL6 25348397 N/A physical interaction ComPPI
MYBBP1A RPS3 25348397 N/A physical interaction ComPPI
MYBBP1A RPS13 25348397 N/A physical interaction ComPPI
MYBBP1A RPL23A 25348397 N/A physical interaction ComPPI
MYBBP1A RPS6 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MYBBP1A EEF1A1 25348397 N/A physical interaction ComPPI
MYBBP1A EEF1A1P5 25348397 N/A physical interaction ComPPI
MYBBP1A RSL1D1 25348397 N/A physical interaction ComPPI
MYBBP1A RPL18 25348397 N/A physical interaction ComPPI
MYBBP1A RPS2 25348397 N/A physical interaction ComPPI
MYBBP1A RPL5 25348397 N/A physical interaction ComPPI
MYBBP1A RPS11 25348397 N/A physical interaction ComPPI
MYBBP1A RPS24 25348397 N/A physical interaction ComPPI
MYBBP1A RPS23 25348397 N/A physical interaction ComPPI
MYBBP1A RPS8 25348397 N/A physical interaction ComPPI
MYBBP1A RNPS1 25348397 N/A physical interaction ComPPI
MYBBP1A FTSJ3 25348397 N/A physical interaction ComPPI
MYBBP1A CAVIN1 25348397 N/A physical interaction ComPPI
MYBBP1A NOP16 25348397 N/A physical interaction ComPPI
MYBBP1A HNRNPA0 25348397 N/A physical interaction ComPPI
MYBBP1A NCSTN 25348397 N/A physical interaction ComPPI
MYBBP1A HNRNPR 25348397 N/A physical interaction ComPPI
MYBBP1A ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
MYBBP1A TP53 25348397 N/A physical interaction ComPPI
MYBBP1A SRPK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MYBBP1A TARDBP 25348397 N/A physical interaction ComPPI
MYBBP1A RELA 25348397 N/A physical interaction ComPPI
MYBBP1A LGR4 25348397 N/A physical interaction ComPPI
MYBBP1A STAU1 25348397 N/A physical interaction ComPPI
MYBBP1A CUL7 25348397 N/A physical interaction ComPPI
MYBBP1A OBSL1 25348397 N/A physical interaction ComPPI
MYBBP1A CCDC8 25348397 N/A physical interaction ComPPI
MYBBP1A EED 25348397 N/A physical interaction ComPPI
MYBBP1A RNF2 25348397 N/A physical interaction ComPPI
MYBBP1A BSG 25348397 N/A physical interaction ComPPI
MYBBP1A ZBTB38 25348397 N/A physical interaction ComPPI
MYBBP1A PRR11 25348397 N/A physical interaction ComPPI
MYBBP1A NSD2 25348397 N/A physical interaction ComPPI
MYBBP1A PRPF8 25348397 N/A physical interaction ComPPI
MYBBP1A NTRK1 25348397 N/A physical interaction ComPPI
MYBBP1A HNRNPU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A MYH6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBBP1A PES1 25348397 N/A physical interaction ComPPI
MYBBP1A C1ORF131 25348397 N/A physical interaction ComPPI
MYBBP1A ZNF746 25348397 N/A physical interaction ComPPI
MYBBP1A CDC14B 25348397 N/A physical interaction ComPPI
MYBBP1A PUM3 25348397 N/A physical interaction ComPPI
MYBBP1A RBM34 25348397 N/A physical interaction ComPPI
MYBBP1A MACROH2A2 25348397 N/A physical interaction ComPPI
MYBBP1A MECP2 25348397 N/A physical interaction ComPPI
MYBBP1A RPL30 25348397 N/A physical interaction ComPPI
MYBBP1A RRP8 25348397 N/A physical interaction ComPPI
MYBBP1A FGF8 25348397 N/A physical interaction ComPPI
MYBBP1A PDGFB 25348397 N/A physical interaction ComPPI
MYBBP1A RPL18A 25348397 N/A physical interaction ComPPI
MYBBP1A SRP68 25348397 N/A physical interaction ComPPI
MYBBP1A CDX1 25348397 N/A physical interaction ComPPI
MYBBP1A PLEKHO1 25348397 N/A physical interaction ComPPI
MYBBP1A KNOP1 25348397 N/A physical interaction ComPPI
MYBBP1A MAGEB10 25348397 N/A physical interaction ComPPI
MYBBP1A CCDC59 25348397 N/A physical interaction ComPPI
MYBBP1A MTARC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MYBBP1A SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MYBBP1A TRIM25 25348397 N/A physical interaction ComPPI
MYBBP1A BRCA1 25348397 N/A physical interaction ComPPI
MYBBP1A MTF1 25348397 N/A physical interaction ComPPI
MYBBP1A NFKB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYBBP1A MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A MED29 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A ESR2 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
MYBBP1A GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MYBBP1A E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
MYBBP1A VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
MYBBP1A YY1 23531880 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A CHEK2 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MYBBP1A DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
MYBBP1A RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYBBP1A AURKB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MYBBP1A FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MAP3K14 MYBBP1A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
H3C1 MYBBP1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ILF2 MYBBP1A 25348397 N/A physical interaction ComPPI
POLR1A MYBBP1A 25348397 N/A physical interaction ComPPI
AURKAIP1 MYBBP1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPL14 MYBBP1A 25348397 N/A physical interaction ComPPI
WDR5 MYBBP1A 25348397 N/A physical interaction ComPPI
IK MYBBP1A 25348397 N/A physical interaction ComPPI
RPS14 MYBBP1A 25348397 N/A physical interaction ComPPI
LYAR MYBBP1A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF1D MYBBP1A 25348397 N/A physical interaction ComPPI
TRIM44 MYBBP1A 25348397 N/A physical interaction ComPPI
RRP7A MYBBP1A 25348397 N/A physical interaction ComPPI
MYBBP1A MYB 14525934 27898060 8302594 9447996 N/A experimental interaction detection HPRD,OmniPath
METTL14 MYBBP1A 24234451 29507755 association anti tag coimmunoprecipitation IntAct
PLEC MYBBP1A 24234451 30021884 physical association cross-linking study IntAct
L1TD1 MYBBP1A 24234451 25702638 association anti bait coimmunoprecipitation IntAct
MYOD1 MYBBP1A 22333916 27898060 N/A N/A OmniPath
AURKB MYBBP1A 20177074 27898060 N/A N/A OmniPath

Visualization










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