Gene Information gene info

  1. Home

GENE：TFDP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TFDP1
FullNmae transcription factor Dp-1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11749
EnsembleID ENSG00000198176
Uniprot Q14186

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TFDP1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TFDP1 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TFDP1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TFDP1 apoptosis 39815900 TFDP1 overexpression repressed viability, promoted apoptosis, increased expressions of Bax, Cleaved caspase 3, MMP9 and ADAM15, and decreased Bcl-2 expression in NPCs, while TFDP1 silencing did conversely. retulator signature
TFDP1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
TFDP1 anoikis 36726781 Four anoikis-related genes(SNAI2, TFDP1, IKBKG, and MCL1) with significant differential expression were selected through Cox regression and LASSO analyses. retulator signature

Go Annotation:

GeneSymbol Go id
TFDP1 GO:0000083,GO:0000083,GO:0000785,GO:0000977,GO:0000977,GO:0000981,GO:0000981,GO:0000987,GO:0001228,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0006357,GO:0006366,GO:0008544,GO:0019904,GO:0035189,GO:0035189,GO:0043276,GO:0045944,GO:0051091,GO:0070345,GO:0090575,GO:0090575,GO:0090575,GO:0140297,GO:1900087,GO:2000278

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TFDP1 hsa:7027 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
TFDP1 hsa:7027 path:hsa04110 Cell cycle - Homo sapiens (human)
TFDP1 hsa:7027 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TFDP1 SOCS3 18687693 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
CCNE1 TFDP1 18687693 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR2 TFDP1 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TFDP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TFDP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RB1 TFDP1 8223441 trascriptional regulation,stimulation inferred by curator TFlink
RBL1 TFDP1 8223441 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000033EBB8 TFDP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 TFDP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA TFDP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003677B2 TFDP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 TFDP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075A611 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000053B1E8 TFDP1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 TFDP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD TFDP1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 TFDP1 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 TFDP1 22135298 phosphorylation N/A PhosphoSite
RBBP4 TFDP1 25361965 interaction type N/A PTMCode2
TFDP1 RBBP4 25361965 interaction type N/A PTMCode2
TFDP1 CDK3 25361965 interaction type N/A PTMCode2
CDK3 TFDP1 25361965 interaction type N/A PTMCode2
TP53 TFDP1 25361965 interaction type N/A PTMCode2
TFDP1 TP53 25361965 interaction type N/A PTMCode2
CCNE1 TFDP1 25361965 interaction type N/A PTMCode2
TFDP1 CCNE1 25361965 interaction type N/A PTMCode2
SERTAD2 TFDP1 25361965 interaction type N/A PTMCode2
TFDP1 SERTAD2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SOCS3 TFDP1 25348397 N/A physical interaction ComPPI
GMNN TFDP1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCBP1 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
NPDC1 TFDP1 11042687 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CDK6 TFDP1 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
LIN37 TFDP1 17531812 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 TFDP1 25348397 N/A physical interaction ComPPI
E2F6 TFDP1 16189514 24234451 25348397 25416956 26871637 27705803 association,physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RING1 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RYBP TFDP1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
NLK TFDP1 22773187 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CBX1 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RB1 TFDP1 16360038 24234451 25348397 27705803 association,physical association coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
CREBBP TFDP1 25348397 N/A physical interaction ComPPI
SIAH1 TFDP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ABCD3 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
ARF3 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
AXIN1 TFDP1 22773187 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
APOD TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RBL2 TFDP1 17531812 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F1 TFDP1 14525934 16360038 22327218 24234451 25348397 27705803 8405995 8816502 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,pull down,x-ray crystallography,physical interaction,comigration in non denaturing gel electrophoresis,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
E2F2 TFDP1 14525934 24234451 25348397 27705803 7739537 8755520 association experimental interaction detection,physical interaction,comigration in non denaturing gel electrophoresis,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
E2F4 TFDP1 10540350 14525934 16360038 24234451 25348397 27705803 association,physical association experimental interaction detection,isothermal titration calorimetry,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach ComPPI,HPRD,IntAct
LIN9 TFDP1 17531812 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F5 TFDP1 14525934 24234451 25348397 27705803 7760804 association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
DVL1 TFDP1 22773187 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
ZRANB2 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
DVL2 TFDP1 22773187 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDK2 TFDP1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC2 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CDC20 TFDP1 25348397 N/A physical interaction ComPPI
CCT5 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
MXD1 TFDP1 25348397 N/A physical interaction ComPPI
RNF2 TFDP1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 SERTAD2 11331592 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TFDP1 TP53 14525934 25348397 8816502 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TFDP1 CDK3 25348397 N/A physical interaction ComPPI
TFDP1 RBL1 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction ComPPI
TFDP1 LIN54 17531812 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TFDP1 ELAVL1 25348397 N/A physical interaction ComPPI
TFDP1 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 CDK1 25348397 N/A physical interaction ComPPI
TFDP1 PRPF31 25348397 N/A physical interaction ComPPI
TFDP1 E2F3 14525934 24234451 25348397 27705803 7739537 8755520 association experimental interaction detection,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
TFDP1 CDC27 25348397 N/A physical interaction ComPPI
TFDP1 ANAPC5 25348397 N/A physical interaction ComPPI
TFDP1 MIER2 25348397 N/A physical interaction ComPPI
TFDP1 COMMD4 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 CDT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TFDP1 MAX 24234451 25348397 25609649 27705803 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 L3MBTL2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 GGA1 25348397 N/A physical interaction ComPPI
TFDP1 COMMD8 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 COMMD1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 COMMD6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 HDAC1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 CBX3 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 MCIDAS 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 AKAP8 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 TUBA1C 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 ATP2A2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 MGA 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 RPL35A 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 ATP5MK 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 NTPCR 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 CCT8 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 GLUD1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 RCN2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 CAND1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 SLC25A10 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 TRIM28 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP1 ERLIN2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
WDR5 TFDP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
SOCS3 TFDP1 18687693 27898060 inhibition N/A OmniPath
TFDP1 E2F1 14618416 16360038 22629304 25368385 27898060 7739537 7892279 8405995 8657117 8816502 8816798 8832394 9199321 9464260 9501179 9704927 9780002 stimulant N/A OmniPath

Visualization










  Return