Gene Information gene info

GENE:TSC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TSC2
FullNmae TSC complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12363
EnsembleID ENSG00000103197
Uniprot P49815

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TSC2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
TSC2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC2 anoikis 27882343 Depletion of Bim by siRNA in TSC2-deficient cells resulted in anoikis resistance. retulator signature

Go Annotation:

GeneSymbol Go id
TSC2 GO:0001843,GO:0005096,GO:0005096,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005764,GO:0005765,GO:0005794,GO:0005829,GO:0005829,GO:0006469,GO:0006606,GO:0006897,GO:0007507,GO:0008104,GO:0008285,GO:0009267,GO:0014069,GO:0014069,GO:0016020,GO:0016192,GO:0016239,GO:0019902,GO:0030100,GO:0030178,GO:0031267,GO:0032007,GO:0032007,GO:0032007,GO:0033596,GO:0033596,GO:0033596,GO:0042803,GO:0043276,GO:0043491,GO:0046626,GO:0046627,GO:0048009,GO:0048471,GO:0050918,GO:0051056,GO:0051726,GO:0051879,GO:0051898,GO:0051898,GO:1901525,GO:1904262

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TSC2 hsa:7249 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04140 Autophagy - animal - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04218 Cellular senescence - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04714 Thermogenesis - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
TSC2 hsa:7249 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
TSC2 hsa:7249 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
TSC2 hsa:7249 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
TSC2 hsa:7249 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TSC2 TSC1 10807585 10915759 11175345 11290735 11741832 11741833 12150915 12167664 12172553 12176984 12869586 12906785 14551205 14651849 15342917 15611338 15851026 15851513 15963462 16339216 16424383 16556040 16636147 16678438 16959574 17077083 17604271 17658474 17680028 17693255 18198340 18411301 18481918 18692468 18974095 19022819 19027299 19339977 20146692 20226003 21071413 21533173 21621563 21708191 23030059 23180781 23331499 26192618 26597054 27328425 9069260 9580671 phosphorylation reaction,stimulation,association,physical association anti tag coimmunoprecipitation,protein kinase assay ACSN,InnateDB,SignaLink,SignaLink
RBX1 TSC2 11900249 12648680 12820959 12906785 15340381 15459660 15688063 15703371 16636147 16697054 17680028 17884153 18381890 18931676 19022819 19440234 19622404 19686080 19809470 19847258 20146692 20211143 26192618 interaction type N/A ACSN
TSC2 RHEB 12842888 12906785 15854902 16636147 17680028 19022819 20146692 20226003 21071413 23180781 23331499 26192618 interaction type,stimulation,physical association pull down ACSN,InnateDB,SignaLink,SignaLink
AKT1 TSC2 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 26192618 9812896 interaction type N/A ACSN
SESN2 TSC2 14651849 15509864 15980064 16054095 16054096 17244528 18692468 19037093 19197243 19339977 20484410 26192618 interaction type N/A ACSN
DDIT4 TSC2 18198340 19557001 26192618 interaction type N/A ACSN
DAPK1 TSC2 11323415 17703233 18974095 19180116 26192618 interaction type N/A ACSN
NAA10 TSC2 20145209 26192618 interaction type N/A ACSN
TSC2 GSK3B 12511557 15972957 16959574 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
TSC2 RICTOR 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 MAPKAP1 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 MLST8 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 AKT1 18411301 23180781 phosphorylation reaction protein kinase assay InnateDB
TSC2 MTOR 18411301 23180781 phosphorylation reaction protein kinase assay InnateDB
TSC2 MYCBP2 14559897 19000755 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
TSC2 YWHAZ 12176984 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
TSC2 YWHAB 12364343 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 YWHAG 12438239 23180781 physical association pull down InnateDB
TSC2 CALM3 11811958 23180781 physical association far western blotting InnateDB
TSC2 CCNA2 11444800 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 CCNB1 11444800 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 CDK1 11444800 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 PATJ 17234746 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
TSC2 HSPA1B 15963462 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 HSPA8 15963462 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 ESR1 15039427 15851513 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
AXIN1 TSC2 15972957 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 DVL2 15972957 23180781 physical association anti tag coimmunoprecipitation InnateDB
RB1CC1 TSC2 16043512 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 FOXO1 17077083 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 DAPK1 18974095 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 NEK1 14690447 23180781 physical association two hybrid InnateDB
TSC2 CDKN1B 15355997 17470459 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDKN1B TSC2 15355997 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 PLK1 16339216 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 TBC1D7 17658474 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBC1D7 TSC2 17658474 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
TSC1 TSC2 17658474 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 YWHAE 16636147 23180781 physical association pull down InnateDB
TSC2 YWHAQ 17470459 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 CUL4A 18381890 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 PPP2CA 18487611 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD2 TSC2 15066998 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK1 TSC2 15851026 23180781 physical association anti tag coimmunoprecipitation InnateDB
NEFL TSC2 12226091 23180781 physical association pull down InnateDB
GSK3A TSC2 20226003 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
AR TSC2 20610535 21036700 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
MYC TSC2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TSC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE TSC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 TSC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA TSC2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAPKAPK2 TSC2 22135298 phosphorylation N/A PhosphoSite
MAPK3 TSC2 22135298 phosphorylation N/A PhosphoSite
MAPK1 TSC2 22135298 phosphorylation N/A PhosphoSite
RPS6KA1 TSC2 22135298 phosphorylation N/A PhosphoSite
AKT1 TSC2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIN1 TSC2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CIAO1 TSC2 25348397 N/A physical interaction ComPPI
TBC1D7 TSC2 25348397 N/A physical interaction ComPPI
CCND1 TSC2 14525934 16357142 24234451 25348397 26977878 27898060 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
TK1 TSC2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDKN1B TSC2 14525934 15355997 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
YWHAG TSC2 12364343 12438239 14525934 24234451 25348397 association,physical association coimmunoprecipitation,experimental interaction detection,filter binding,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CALM1 TSC2 25348397 N/A physical interaction ComPPI
MDFI TSC2 25348397 N/A physical interaction ComPPI
CBY1 TSC2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAPK1 TSC2 14525934 15342917 15851026 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK3 TSC2 14525934 15342917 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRB2 TSC2 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD2 TSC2 14525934 15066998 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD3 TSC2 14525934 15066998 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GSK3B TSC2 12511557 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PAM TSC2 14525934 14559897 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
YWHAB TSC2 12364343 12438239 12468542 12582162 14525934 15324660 17353931 20169078 24234451 24255178 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
YWHAZ TSC2 12176984 12364343 12438239 12468542 14525934 15161933 16636147 20618440 24234451 25348397 association,physical association two hybrid,experimental interaction detection,far western blotting,filter binding,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
PRKAA1 TSC2 25348397 N/A physical interaction ComPPI
NTRK1 TSC2 25348397 N/A physical interaction ComPPI
HERC1 TSC2 25348397 N/A physical interaction ComPPI
AXIN1 TSC2 25348397 N/A physical interaction ComPPI
CAV1 TSC2 25348397 N/A physical interaction ComPPI
PLK1 TSC2 25348397 N/A physical interaction ComPPI
PPP1CA TSC2 19389623 24234451 25348397 physical association far western blotting,pull down ComPPI,IntAct
RALA TSC2 25348397 N/A physical interaction ComPPI
RPS6KA1 TSC2 14525934 15342917 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AKT3 TSC2 12167664 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PPP2CA TSC2 14525934 17163575 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RABEP1 TSC2 14525934 25348397 9045618 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
RAB5A TSC2 14525934 25348397 9045618 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TSC2 SFN 12364343 12438239 14525934 24234451 25348397 N/A experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
TSC2 RHEB 12842888 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TSC2 YWHAE 12438239 14525934 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
TSC2 TSC1 10585443 10915759 11175345 11290735 11741833 12511557 12869586 14525934 15342917 15963462 16424383 17658474 17693255 20412061 21134130 24234451 25263562 25348397 9580671 9809973 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
TSC2 NEK1 14525934 14690447 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TSC2 MAPKAPK2 12582162 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TSC2 YWHAH 12438239 14525934 17979178 24234451 25348397 association experimental interaction detection,pull down,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
TSC2 ESR1 14525934 15851513 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TSC2 AKT2 25348397 N/A in vivo ComPPI
TSC2 FBXW5 14525934 18381890 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
TSC2 FBXL6 25348397 N/A two hybrid,in vitro ComPPI
TSC2 AKT1 12150915 12438239 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TSC2 RAP1A 25348397 N/A physical interaction ComPPI
TSC2 FOXO1 25348397 N/A physical interaction ComPPI
TSC2 PTK2 25348397 N/A physical interaction ComPPI
TSC2 CCND2 25348397 N/A physical interaction ComPPI
TSC2 CCND3 25348397 N/A physical interaction ComPPI
TSC2 UBE3A 25348397 N/A physical interaction ComPPI
TSC2 LNX1 25348397 N/A physical interaction ComPPI
TSC2 TIGAR 25348397 N/A physical interaction ComPPI
TSC2 HECW2 25348397 N/A physical interaction ComPPI
TSC2 CBY2 25348397 N/A physical interaction ComPPI
TSC2 SIRT1 20169165 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
TSC2 DAPK1 21134130 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC2 RRAGA 24529380 25348397 25936802 27898060 N/A physical interaction ComPPI,OmniPath
TSC2 RRAGB 25348397 N/A physical interaction ComPPI
TSC2 RRAGC 25348397 N/A physical interaction ComPPI
TSC2 RRAGD 25348397 N/A physical interaction ComPPI
TSC2 SPINT2 25348397 N/A physical interaction ComPPI
TSC2 PNKD 25348397 N/A physical interaction ComPPI
TSC2 RP2 25348397 N/A physical interaction ComPPI
TSC2 PRKCSH 25348397 N/A physical interaction ComPPI
TSC2 ALDH3A2 25348397 N/A physical interaction ComPPI
TSC2 POU5F1 25348397 N/A physical interaction ComPPI
TSC2 COL20A1 25348397 N/A physical interaction ComPPI
TSC2 CD79B 25348397 N/A physical interaction ComPPI
TSC2 CD83 25348397 N/A physical interaction ComPPI
TSC2 SIGLECL1 25348397 N/A physical interaction ComPPI
TSC2 P4HA3 25348397 N/A physical interaction ComPPI
TSC2 FAM221B 25348397 N/A physical interaction ComPPI
TSC2 P4HA2 25348397 N/A physical interaction ComPPI
TSC2 RUVBL2 25348397 N/A physical interaction ComPPI
TSC2 DNAAF10 25348397 N/A physical interaction ComPPI
TSC2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TSC2 CDK4 24234451 25348397 26977878 physical association anti tag coimmunoprecipitation ComPPI,IntAct
TSC2 SGK1 24234451 25348397 27451907 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescent resonance energy transfer ComPPI,IntAct
YWHAQ TSC2 12438239 14525934 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PRKAA2 TSC2 14651849 16959574 27898060 stimulant N/A OmniPath
PRKCA TSC2 11290735 15342917 27898060 N/A N/A OmniPath
TSC2 HSPA8 15963462 27898060 N/A N/A OmniPath
TSC2 YWHAG 12364343 12438239 27898060 N/A N/A OmniPath
YWHAG TSC2 12364343 12438239 27898060 N/A N/A OmniPath
PLK1 TSC2 16339216 27898060 N/A N/A OmniPath
MAPKAPK2 TSC2 12582162 15963462 18075516 27898060 inhibition,stimulant N/A OmniPath
CHUK TSC2 18490760 27898060 inhibition N/A OmniPath
CDKN1B TSC2 15355997 17470459 27898060 N/A N/A OmniPath
RPS6KA1 TSC2 15342917 15757502 15963462 16244323 17081983 19690332 20068231 27898060 inhibition N/A OmniPath
TSC2 FOXO1 17077083 27898060 N/A N/A OmniPath
ESR1 TSC2 15039427 15851513 27898060 N/A N/A OmniPath
MLST8 TSC2 18411301 27898060 N/A N/A OmniPath
AKT1 TSC2 12150915 12167664 12172553 12438239 12582162 15342917 15661536 16288292 16636147 16702951 17018601 17386267 18411301 18466115 18707149 19664994 19690332 20169078 24782546 27898060 inhibition N/A OmniPath
TSC2 AKT1 12150915 12167664 12438239 15342917 18411301 18466115 27898060 N/A N/A OmniPath
GSK3A TSC2 16959574 20226003 27898060 stimulant N/A OmniPath
RICTOR TSC2 18411301 27898060 N/A N/A OmniPath
TSC2 YWHAZ 12176984 12364343 12438239 12468542 15161933 16636147 22001647 27898060 N/A N/A OmniPath
YWHAZ TSC2 12176984 12364343 12438239 12468542 15161933 16636147 22001647 27898060 N/A N/A OmniPath
TSC2 RHEB 12771962 12820960 12842888 12869586 12906785 15340059 15854902 16636147 17077083 20226003 27898060 inhibition,stimulant N/A OmniPath
RHEB TSC2 12771962 12820960 12842888 12869586 15340059 15854902 16636147 17077083 20226003 27898060 N/A N/A OmniPath
MAPK3 TSC2 15342917 16244323 19188143 27898060 inhibition N/A OmniPath
TP53 TSC2 18431400 27898060 stimulant N/A OmniPath
TSC2 CDK1 11444800 27898060 N/A N/A OmniPath
TSC2 CCNA2 11444800 27898060 N/A N/A OmniPath
TSC2 SMAD2 15066998 27898060 N/A N/A OmniPath
RPS6KA3 TSC2 16244323 27898060 inhibition N/A OmniPath
MAPK1 TSC2 12150915 12438239 15342917 15851026 15963462 27898060 inhibition N/A OmniPath
TSC2 CCNB1 11444800 27898060 N/A N/A OmniPath
PPP2CA TSC2 17163575 18487611 27898060 N/A N/A OmniPath
AKT2 TSC2 12150915 12167664 12172553 19188143 27898060 inhibition N/A OmniPath
TSC2 DAPK1 18974095 21134130 27898060 N/A N/A OmniPath
DAPK1 TSC2 18974095 21134130 27898060 inhibition,stimulant N/A OmniPath
TSC2 MTOR 12271141 18411301 27898060 inhibition,stimulant N/A OmniPath
TSC2 GSK3B 12511557 15972957 16959574 27898060 N/A N/A OmniPath
GSK3B TSC2 12511557 15972957 16959574 27898060 stimulant N/A OmniPath
YWHAQ TSC2 12438239 15161933 17353931 17470459 20618440 27898060 N/A N/A OmniPath
TSC2 YWHAQ 12438239 15161933 17353931 17470459 20618440 27898060 N/A N/A OmniPath
CUL4A TSC2 18381890 27898060 stimulant N/A OmniPath
TSC2 TSC1 10585443 10807585 10915759 11175345 11290735 11741832 11741833 12147258 12167664 12176984 12511557 12869586 14551205 14651849 15340059 15342917 15851026 15851513 15963462 16339216 16424383 16464865 16636147 17077083 17355907 17658474 17693255 18411301 20166753 20412061 21134130 27898060 9580671 9809973 inhibition,stimulant N/A OmniPath
TSC1 TSC2 10585443 10807585 10915759 11175345 11290735 11741832 11741833 12147258 12167664 12176984 12511557 12869586 14551205 14651849 15340059 15342917 15851026 15851513 15963462 16339216 16424383 16464865 16636147 17077083 17355907 17658474 17693255 18411301 20166753 20412061 21134130 27898060 9580671 9809973 stimulant N/A OmniPath
TSC2 DVL2 15972957 27898060 N/A N/A OmniPath
TSC2 YWHAE 12438239 16636147 17979178 19608861 27898060 N/A N/A OmniPath
PATJ TSC2 17234746 27898060 N/A N/A OmniPath
TSC2 TBC1D7 17658474 26186194 27898060 N/A N/A OmniPath
TBC1D7 TSC2 17658474 26186194 27898060 N/A N/A OmniPath
NEK1 TSC2 14690447 27898060 N/A N/A OmniPath
YWHAB TSC2 12176984 12364343 12438239 12468542 12582162 15324660 16636147 17353931 20169078 24255178 27898060 N/A N/A OmniPath
TSC2 YWHAB 12176984 12364343 12438239 12468542 12582162 15324660 16636147 17353931 20169078 24255178 27898060 N/A N/A OmniPath
TSC2 CXCR5 15972957 27898060 N/A N/A OmniPath
TSC2 MYCBP2 14559897 19000755 27898060 N/A N/A OmniPath
MAPKAP1 TSC2 18411301 27898060 N/A N/A OmniPath

Visualization