Gene Information gene info

GENE:CA9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CA9
FullNmae carbonic anhydrase 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1383
EnsembleID ENSG00000107159
Uniprot Q16790

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CA9 alkaliptosis 39937414 In the alkaliptosis gene set (IKBKB, NFKB1, CA9, CHUK, IKBKG, and RELA), NFKB1, CHUK, and IKBKG exhibited differential expression in TCGA-KIRC. retulator signature
CA9 alkaliptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CA9 GO:0001666,GO:0002009,GO:0004089,GO:0004089,GO:0004089,GO:0005515,GO:0005730,GO:0005886,GO:0005886,GO:0005886,GO:0006730,GO:0008270,GO:0009410,GO:0016020,GO:0016323,GO:0031528,GO:0033574,GO:0046903,GO:0140677

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CA9 hsa:768 path:hsa00910 Nitrogen metabolism - Homo sapiens (human)
CA9 hsa:768 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CA9 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOS CA9 11672442 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
HIF1A CA9 12171890 17486380 18971253 19154183 19238077 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 CA9 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 CA9 11672442 12615703 16270297 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SP3 CA9 11672442 12615703 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
EGR1 CA9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CA9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AHR CA9 19154183 trascriptional regulation,stimulation inferred by curator TFlink
ARNT CA9 22387692 trascriptional regulation,stimulation inferred by curator TFlink
ATF4 CA9 19564335 trascriptional regulation,stimulation inferred by curator TFlink
EP300 CA9 16270297 trascriptional regulation,stimulation inferred by curator TFlink
EPAS1 CA9 12171890 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 CA9 18381358 trascriptional regulation,stimulation inferred by curator TFlink
HDAC4 CA9 20110259 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 CA9 12615703 16270297 trascriptional regulation,stimulation inferred by curator TFlink
VHL CA9 15754010 trascriptional regulation,stimulation inferred by curator TFlink
ELK1 CA9 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A CA9 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 CA9 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 CA9 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA CA9 22135298 phosphorylation N/A PhosphoSite
CDH1 CA9 25361965 interaction type N/A PTMCode2
CA9 CDH1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 CA9 25348397 N/A physical interaction ComPPI
GLRX3 CA9 24234451 25348397 26871637 physical association two hybrid,two hybrid array,bimolecular fluorescence complementation,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP5F1B CA9 25348397 N/A physical interaction ComPPI
CA2 CA9 25348397 N/A physical interaction ComPPI
CDH1 CA9 25348397 N/A physical interaction,in vitro,in vivo ComPPI
XPO5 CA9 25348397 N/A physical interaction ComPPI
XPO1 CA9 25348397 N/A physical interaction ComPPI
TNPO1 CA9 25348397 N/A physical interaction ComPPI
IPO7 CA9 25348397 N/A physical interaction ComPPI
CTNNB1 CA9 14525934 14567991 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CSE1L CA9 25348397 N/A physical interaction ComPPI
CA9 CTNNA1 14525934 14567991 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CA9 FLOT1 25348397 N/A physical interaction ComPPI
CA9 CAND1 25348397 N/A physical interaction ComPPI
CA9 G3BP2 25348397 N/A physical interaction ComPPI
CA9 ATP5F1A 25348397 N/A physical interaction ComPPI
CA9 RTCB 25348397 N/A physical interaction ComPPI
CA9 RPS5 25348397 N/A physical interaction ComPPI
CA9 CAND2 25348397 N/A physical interaction ComPPI
CA9 ACACA 25348397 N/A physical interaction ComPPI
CA9 IPO9 25348397 N/A physical interaction ComPPI
CA9 IPO4 25348397 N/A physical interaction ComPPI
CA9 IPO5 25348397 N/A physical interaction ComPPI
CA9 XPOT 25348397 N/A physical interaction ComPPI
CA9 TNPO3 25348397 N/A physical interaction ComPPI
CA9 ATXN10 25348397 N/A physical interaction ComPPI
CA9 HEATR3 25348397 N/A physical interaction ComPPI
CA9 SAAL1 25348397 N/A physical interaction ComPPI
CA9 SRPRB 25348397 N/A physical interaction ComPPI
CA9 HADHA 25348397 N/A physical interaction ComPPI
CA9 ATP4A 25348397 N/A physical interaction ComPPI
CA9 CSRP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CA9 CA9 19805286 24234451 N/A x-ray crystallography IntAct
PRKACA CA9 22037869 27898060 stimulant N/A OmniPath

Visualization