Gene Information gene info

GENE:AASDHPPT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AASDHPPT
FullNmae aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14235
EnsembleID ENSG00000149313
Uniprot Q9NRN7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AASDHPPT cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
AASDHPPT GO:0000287,GO:0005515,GO:0005829,GO:0005829,GO:0005829,GO:0008897,GO:0008897,GO:0008897,GO:0009258,GO:0015939,GO:0019878,GO:0051604,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AASDHPPT hsa:60496 path:hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human)
AASDHPPT hsa:60496 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 AASDHPPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AASDHPPT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000028BB8 AASDHPPT 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 AASDHPPT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 AASDHPPT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 AASDHPPT 19088304 21572407 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000008A99 AASDHPPT 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 AASDHPPT 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 AASDHPPT 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 AASDHPPT 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 AASDHPPT 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000081E1F AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 AASDHPPT 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000E1E9E AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 AASDHPPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 AASDHPPT 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF1B AASDHPPT 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CRX AASDHPPT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGTA AASDHPPT 25348397 N/A physical interaction ComPPI
MDFI AASDHPPT 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPP1R3C AASDHPPT 25348397 N/A physical interaction ComPPI
JUN AASDHPPT 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2D2 AASDHPPT 25348397 N/A physical interaction ComPPI
PAXIP1 AASDHPPT 25348397 N/A physical interaction ComPPI
SIAH1 AASDHPPT 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DLD AASDHPPT 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 AASDHPPT 25348397 N/A physical interaction ComPPI
TRAF2 AASDHPPT 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
HNRNPH1 AASDHPPT 25348397 N/A physical interaction ComPPI
NOL3 AASDHPPT 25348397 N/A physical interaction ComPPI
RAE1 AASDHPPT 25348397 N/A physical interaction ComPPI
SOD1 AASDHPPT 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TRIP13 AASDHPPT 25348397 N/A physical interaction ComPPI
DAZAP1 AASDHPPT 25348397 N/A physical interaction ComPPI
EHD1 AASDHPPT 25348397 N/A physical interaction ComPPI
ULK2 AASDHPPT 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ADSS2 AASDHPPT 25348397 N/A physical interaction ComPPI
HNRNPA1 AASDHPPT 25348397 N/A physical interaction ComPPI
STIL AASDHPPT 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AASDHPPT USP22 19615732 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AASDHPPT BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AASDHPPT FBXO6 25348397 N/A physical interaction ComPPI
AASDHPPT CAPZA2 25348397 N/A physical interaction ComPPI
AASDHPPT PLCG1 25348397 N/A physical interaction ComPPI
AASDHPPT ZC3HC1 25348397 N/A physical interaction ComPPI
AASDHPPT MOV10 25348397 N/A physical interaction ComPPI
AASDHPPT NXF1 25348397 N/A physical interaction ComPPI
AASDHPPT ANGPTL4 25348397 N/A physical interaction ComPPI
AASDHPPT HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
AASDHPPT SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AASDHPPT PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization