GENE:AASDHPPT
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | AASDHPPT |
FullNmae | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:14235 |
EnsembleID | ENSG00000149313 |
Uniprot | Q9NRN7 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
AASDHPPT | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
GeneSymbol | Go id |
---|---|
AASDHPPT | GO:0000287,GO:0005515,GO:0005829,GO:0005829,GO:0005829,GO:0008897,GO:0008897,GO:0008897,GO:0009258,GO:0015939,GO:0019878,GO:0051604,GO:0070062 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
AASDHPPT | hsa:60496 | path:hsa00770 | Pantothenate and CoA biosynthesis - Homo sapiens (human) |
AASDHPPT | hsa:60496 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SMARCA4 | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ETS1 | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | AASDHPPT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | AASDHPPT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000028BB8 | AASDHPPT | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000F31F4 | AASDHPPT | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | AASDHPPT | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000122ED0 | AASDHPPT | 19088304 21572407 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
URS0000008A99 | AASDHPPT | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000021D7C8 | AASDHPPT | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000020CEC2 | AASDHPPT | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007F792 | AASDHPPT | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000046CDA6 | AASDHPPT | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005E6F45 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000081E1F | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000170CF4 | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004719AB | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EBD4B | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C28B2 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016E46F | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C04A2 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002F8148 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000324096 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FFA8C | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003BD367 | AASDHPPT | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000E1E9E | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000202460 | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FA24D | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003BBF48 | AASDHPPT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B341F | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000321A1A | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000100748 | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003758F0 | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001F5B39 | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C7B2B | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EED18 | AASDHPPT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EIF1B | AASDHPPT | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
CRX | AASDHPPT | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SGTA | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
MDFI | AASDHPPT | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
PPP1R3C | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
JUN | AASDHPPT | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
UBE2D2 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
PAXIP1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
SIAH1 | AASDHPPT | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
DLD | AASDHPPT | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
NTRK1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
TRAF2 | AASDHPPT | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
HNRNPH1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
NOL3 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
RAE1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
SOD1 | AASDHPPT | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
TRIP13 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
DAZAP1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
EHD1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
ULK2 | AASDHPPT | 20562859 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
ADSS2 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
HNRNPA1 | AASDHPPT | 25348397 | N/A | physical interaction | ComPPI |
STIL | AASDHPPT | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
AASDHPPT | USP22 | 19615732 24234451 25348397 25416956 | physical association | anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
AASDHPPT | BABAM1 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
AASDHPPT | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | CAPZA2 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | PLCG1 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | ZC3HC1 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | ANGPTL4 | 25348397 | N/A | physical interaction | ComPPI |
AASDHPPT | HLA-B | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
AASDHPPT | SLX4 | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
AASDHPPT | PLEKHA7 | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |