GENE：ABCB10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ABCB10 |
| FullNmae | ATP binding cassette subfamily B member 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:41 |
| EnsembleID | ENSG00000135776 |
| Uniprot | Q9NRK6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ABCB10 | cuproptosis | 36313717 | The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. | Genes related to copper homeostasis pathway |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ABCB10 | GO:0005515,GO:0005524,GO:0005739,GO:0005743,GO:0006783,GO:0006839,GO:0016887,GO:0031966,GO:0034514,GO:0042803,GO:0045648,GO:0046985,GO:0048821,GO:0055085,GO:0070455,GO:0140359 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ABCB10 | hsa:23456 | path:hsa02010 | ABC transporters - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | ABCB10 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | ABCB10 | 20034404 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | ABCB10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ABCB10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ABCB10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ABCB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ABCB10 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F2 | ABCB10 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | ABCB10 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | ABCB10 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | ABCB10 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000065D58 | ABCB10 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000324096 | ABCB10 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KCNA5 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| CFTR | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| BAK1 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| IL9R | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| ECSIT | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| HLA-DPA1 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| NRG1 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| SNX4 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| COX6B1 | ABCB10 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| NDUFA2 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| NDUFB11 | ABCB10 | 25348397 | N/A | physical interaction | ComPPI |
| ABCB10 | KCNC4 | 25348397 | N/A | physical interaction | ComPPI |