Gene Information gene info

GENE:ABCB8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ABCB8
FullNmae ATP binding cassette subfamily B member 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:49
EnsembleID ENSG00000197150
Uniprot Q9NUT2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ABCB8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ABCB8 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. Genes related to copper homeostasis pathway

Go Annotation:

GeneSymbol Go id
ABCB8 GO:0005515,GO:0005524,GO:0005654,GO:0005730,GO:0005739,GO:0005743,GO:0006884,GO:0015440,GO:0015833,GO:0016887,GO:0031966,GO:0043190,GO:0055085,GO:0062157,GO:0062157,GO:0071805,GO:0140141

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ABCB8 hsa:11194 path:hsa02010 ABC transporters - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ABCB8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ABCB8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ABCB8 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ABCB8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 ABCB8 21046154 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 ABCB8 21046154 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 ABCB8 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SAT1 ABCB8 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FMNL1 ABCB8 25348397 N/A physical interaction ComPPI
PROCR ABCB8 25348397 N/A physical interaction ComPPI
CFTR ABCB8 25348397 N/A physical interaction ComPPI
RASGRP1 ABCB8 25348397 N/A physical interaction ComPPI
GPR37 ABCB8 25348397 N/A physical interaction ComPPI
RAB11FIP5 ABCB8 25348397 N/A physical interaction ComPPI
ABCB8 CLEC2D 25348397 N/A physical interaction ComPPI
ABCB8 LPAR1 25348397 N/A physical interaction ComPPI
ABCB8 NCR3LG1 25348397 N/A physical interaction ComPPI
ABCB8 SLC15A1 25348397 N/A physical interaction ComPPI
ABCB8 SLC1A5 25348397 N/A physical interaction ComPPI

Visualization