GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ABCB8
FullNmae
ATP binding cassette subfamily B member 8
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:49
EnsembleID
ENSG00000197150
Uniprot
Q9NUT2
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ABCB8
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
ABCB8
cuproptosis
36313717
The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1.
Genes related to copper homeostasis pathway
Go Annotation:
GeneSymbol
Go id
ABCB8
GO:0005515,GO:0005524,GO:0005654,GO:0005730,GO:0005739,GO:0005743,GO:0006884,GO:0015440,GO:0015833,GO:0016887,GO:0031966,GO:0043190,GO:0055085,GO:0062157,GO:0062157,GO:0071805,GO:0140141
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
ABCB8
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA1
ABCB8
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
GATA2
ABCB8
18971253
19941826
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
ZNF263
ABCB8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SP1
ABCB8
21046154
trascriptional regulation,stimulation
inferred by curator
TFlink
DAND5
ABCB8
21046154
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000324096
ABCB8
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
SAT1
ABCB8
16169070
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach
ComPPI,IntAct
FMNL1
ABCB8
25348397
N/A
physical interaction
ComPPI
PROCR
ABCB8
25348397
N/A
physical interaction
ComPPI
CFTR
ABCB8
25348397
N/A
physical interaction
ComPPI
RASGRP1
ABCB8
25348397
N/A
physical interaction
ComPPI
GPR37
ABCB8
25348397
N/A
physical interaction
ComPPI
RAB11FIP5
ABCB8
25348397
N/A
physical interaction
ComPPI
ABCB8
CLEC2D
25348397
N/A
physical interaction
ComPPI
ABCB8
LPAR1
25348397
N/A
physical interaction
ComPPI
ABCB8
NCR3LG1
25348397
N/A
physical interaction
ComPPI
ABCB8
SLC15A1
25348397
N/A
physical interaction
ComPPI
ABCB8
SLC1A5
25348397
N/A
physical interaction
ComPPI
Visualization