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GENE：ABCE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ABCE1
FullNmae ATP binding cassette subfamily E member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:69
EnsembleID ENSG00000164163
Uniprot P61221

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ABCE1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
ABCE1 GO:0000054,GO:0003924,GO:0005506,GO:0005515,GO:0005524,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005829,GO:0006413,GO:0006415,GO:0006415,GO:0006417,GO:0016020,GO:0016887,GO:0017111,GO:0022626,GO:0032790,GO:0043024,GO:0043273,GO:0051539,GO:0060698,GO:0060702,GO:0072344

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 ABCE1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ABCE1 RNASEL 11265282 11585831 29145629 7539425 9660177 9847332 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
AR ABCE1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ABCE1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 ABCE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 ABCE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ABCE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB ABCE1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB ABCE1 19843643 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004DA9DB ABCE1 19843643 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000076995 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 ABCE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 ABCE1 25416803 26617714 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
RPS16 ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 RPS16 25361965 interaction type N/A PTMCode2
ABCE1 RPL13 25361965 interaction type N/A PTMCode2
RPL13 ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3F 25361965 interaction type N/A PTMCode2
EIF3F ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 RPL4 25361965 interaction type N/A PTMCode2
RPL4 ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3C 25361965 interaction type N/A PTMCode2
EIF3C ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 ETF1 25361965 interaction type N/A PTMCode2
ETF1 ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3B 25361965 interaction type N/A PTMCode2
EIF3B ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3A 25361965 interaction type N/A PTMCode2
EIF3A ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3I 25361965 interaction type N/A PTMCode2
EIF3I ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 MRTO4 25361965 interaction type N/A PTMCode2
MRTO4 ABCE1 25361965 interaction type N/A PTMCode2
EIF3J ABCE1 25361965 interaction type N/A PTMCode2
ABCE1 EIF3J 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 ABCE1 25348397 N/A physical interaction ComPPI
GNG5 ABCE1 25348397 N/A physical interaction ComPPI
DYNLL1 ABCE1 25348397 N/A physical interaction ComPPI
CIAO1 ABCE1 25348397 N/A physical interaction ComPPI
EIF3H ABCE1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBASH3A ABCE1 18006034 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CIAO2B ABCE1 25348397 N/A physical interaction ComPPI
PPP1CC ABCE1 25348397 N/A physical interaction ComPPI
VIM ABCE1 25348397 N/A physical interaction ComPPI
KIF5B ABCE1 25348397 N/A physical interaction ComPPI
SNRPF ABCE1 25348397 N/A physical interaction ComPPI
PSMD14 ABCE1 25348397 N/A physical interaction ComPPI
LMNA ABCE1 25348397 N/A physical interaction ComPPI
PPP1CB ABCE1 25348397 N/A physical interaction ComPPI
MCM2 ABCE1 25348397 N/A physical interaction ComPPI
RAP2B ABCE1 25348397 N/A physical interaction ComPPI
NDUFAF4 ABCE1 25348397 N/A physical interaction ComPPI
CD44 ABCE1 25348397 N/A physical interaction ComPPI
MAPK1 ABCE1 25348397 N/A physical interaction ComPPI
LYN ABCE1 25348397 N/A physical interaction ComPPI
SRC ABCE1 25348397 N/A physical interaction ComPPI
CD59 ABCE1 25348397 N/A physical interaction ComPPI
PPP1R15A ABCE1 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN ABCE1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
USP7 ABCE1 25348397 N/A physical interaction ComPPI
FLNA ABCE1 25348397 N/A physical interaction ComPPI
PRKACA ABCE1 25348397 N/A physical interaction ComPPI
VAPA ABCE1 25348397 N/A physical interaction ComPPI
CUL3 ABCE1 25348397 N/A physical interaction ComPPI
JUP ABCE1 25348397 N/A physical interaction ComPPI
PDIA3 ABCE1 25348397 N/A physical interaction ComPPI
DUT ABCE1 25348397 N/A physical interaction ComPPI
GNAQ ABCE1 25348397 N/A physical interaction ComPPI
PFKL ABCE1 25348397 N/A physical interaction ComPPI
NTRK1 ABCE1 25348397 N/A physical interaction ComPPI
PTPRF ABCE1 25348397 N/A physical interaction ComPPI
ILK ABCE1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RPS3A ABCE1 25348397 N/A physical interaction ComPPI
XRCC5 ABCE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAX1 ABCE1 25348397 N/A physical interaction ComPPI
PSMA5 ABCE1 25348397 N/A physical interaction ComPPI
PTGES3 ABCE1 25348397 N/A physical interaction ComPPI
PEBP1 ABCE1 25348397 N/A physical interaction ComPPI
TTC37 ABCE1 25348397 N/A physical interaction ComPPI
PRKAR2A ABCE1 25348397 N/A physical interaction ComPPI
RALA ABCE1 25348397 N/A physical interaction ComPPI
IQGAP1 ABCE1 25348397 N/A physical interaction ComPPI
SNAP23 ABCE1 25348397 N/A physical interaction ComPPI
PSMD8 ABCE1 25348397 N/A physical interaction ComPPI
EWSR1 ABCE1 25348397 N/A physical interaction ComPPI
PSMD1 ABCE1 25348397 N/A physical interaction ComPPI
PDHA1 ABCE1 25348397 N/A physical interaction ComPPI
EIF3F ABCE1 25348397 N/A physical interaction ComPPI
EEA1 ABCE1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
XPO1 ABCE1 25348397 N/A physical interaction ComPPI
DNAJC7 ABCE1 25348397 N/A physical interaction ComPPI
TBCD ABCE1 25348397 N/A physical interaction ComPPI
TMPO ABCE1 25348397 N/A physical interaction ComPPI
ABCE1 RNASEL 14525934 25348397 7539425 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ABCE1 RNASE2 12578357 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
ABCE1 USP50 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCE1 SIRT7 25348397 N/A physical interaction ComPPI
ABCE1 ITGA4 25348397 N/A physical interaction ComPPI
ABCE1 MMS19 25348397 N/A physical interaction ComPPI
ABCE1 FBXO6 25348397 N/A physical interaction ComPPI
ABCE1 PRKN 25348397 N/A physical interaction ComPPI
ABCE1 AP1B1 25348397 N/A physical interaction ComPPI
ABCE1 DIABLO 25348397 N/A physical interaction ComPPI
ABCE1 DCP2 25348397 N/A physical interaction ComPPI
ABCE1 STAU1 25348397 N/A physical interaction ComPPI
ABCE1 RNF2 25348397 N/A physical interaction ComPPI
ABCE1 ABCF1 25348397 N/A physical interaction ComPPI
ABCE1 FUBP3 25348397 N/A physical interaction ComPPI
ABCE1 CBX3 25348397 N/A physical interaction ComPPI
ABCE1 ABLIM1 25348397 N/A physical interaction ComPPI
ABCE1 CNIH4 25348397 N/A physical interaction ComPPI
ABCE1 NAA10 25348397 N/A physical interaction ComPPI
ABCE1 PSMD4 25348397 N/A physical interaction ComPPI
ABCE1 CORO1C 25348397 N/A physical interaction ComPPI
ABCE1 SRP9 25348397 N/A physical interaction ComPPI
ABCE1 TIMM21 25348397 N/A physical interaction ComPPI
ABCE1 H1-2 25348397 N/A physical interaction ComPPI
ABCE1 EPB41L3 25348397 N/A physical interaction ComPPI
ABCE1 CUL4A 25348397 N/A physical interaction ComPPI
ABCE1 ZNF207 25348397 N/A physical interaction ComPPI
ABCE1 PRCP 25348397 N/A physical interaction ComPPI
ABCE1 TTC29 25348397 N/A physical interaction ComPPI
ABCE1 WDR1 25348397 N/A physical interaction ComPPI
ABCE1 EIF3D 25348397 N/A physical interaction ComPPI
ABCE1 PAK3 25348397 N/A physical interaction ComPPI
ABCE1 TIMM23 25348397 N/A physical interaction ComPPI
ABCE1 PFDN2 25348397 N/A physical interaction ComPPI
ABCE1 H2BC18 25348397 N/A physical interaction ComPPI
ABCE1 FLNB 25348397 N/A physical interaction ComPPI
ABCE1 SAE1 25348397 N/A physical interaction ComPPI
ABCE1 PSMD13 25348397 N/A physical interaction ComPPI
ABCE1 STRAP 25348397 N/A physical interaction ComPPI
ABCE1 WDR77 25348397 N/A physical interaction ComPPI
ABCE1 TPP1 25348397 N/A physical interaction ComPPI
ABCE1 GNS 25348397 N/A physical interaction ComPPI
ABCE1 PPP2R2A 25348397 N/A physical interaction ComPPI
ABCE1 ATP6V1A 25348397 N/A physical interaction ComPPI
ABCE1 ISYNA1 25348397 N/A physical interaction ComPPI
ABCE1 ETF1 25348397 N/A physical interaction ComPPI
ABCE1 CCNY 25348397 N/A physical interaction ComPPI
ABCE1 IMMT 25348397 N/A physical interaction ComPPI
ABCE1 C16ORF96 25348397 N/A physical interaction ComPPI
ABCE1 RRP1B 25348397 N/A physical interaction ComPPI
ABCE1 RFC4 25348397 N/A physical interaction ComPPI
ABCE1 RPL32 25348397 N/A physical interaction ComPPI
ABCE1 TFAM 25348397 N/A physical interaction ComPPI
ABCE1 ELOC 25348397 N/A physical interaction ComPPI
ABCE1 FLOT2 25348397 N/A physical interaction ComPPI
ABCE1 ITPRID2 25348397 N/A physical interaction ComPPI
ABCE1 GSPT1 25348397 N/A physical interaction ComPPI
ABCE1 NAT10 25348397 N/A physical interaction ComPPI
ABCE1 AARS1 25348397 N/A physical interaction ComPPI
ABCE1 MAP4 25348397 N/A physical interaction ComPPI
ABCE1 MYO6 25348397 N/A physical interaction ComPPI
ABCE1 RAVER1 25348397 N/A physical interaction ComPPI
ABCE1 RBBP7 25348397 N/A physical interaction ComPPI
ABCE1 ASNS 25348397 N/A physical interaction ComPPI
ABCE1 FDPS 25348397 N/A physical interaction ComPPI
ABCE1 RRP12 25348397 N/A physical interaction ComPPI
ABCE1 KARS1 25348397 N/A physical interaction ComPPI
ABCE1 EPB41 25348397 N/A physical interaction ComPPI
ABCE1 SFXN4 25348397 N/A physical interaction ComPPI
ABCE1 TSN 25348397 N/A physical interaction ComPPI
ABCE1 RPRD1B 25348397 N/A physical interaction ComPPI
ABCE1 LTO1 25348397 N/A physical interaction ComPPI
ABCE1 SRRM2 25348397 N/A physical interaction ComPPI
ABCE1 SMARCA5 25348397 N/A physical interaction ComPPI
ABCE1 POLR1B 25348397 N/A physical interaction ComPPI
ABCE1 SAFB 25348397 N/A physical interaction ComPPI
ABCE1 RAB35 25348397 N/A physical interaction ComPPI
ABCE1 SUCLG2 25348397 N/A physical interaction ComPPI
ABCE1 MED23 25348397 N/A physical interaction ComPPI
ABCE1 VDAC3 25348397 N/A physical interaction ComPPI
ABCE1 PPM1G 25348397 N/A physical interaction ComPPI
ABCE1 MFGE8 25348397 N/A physical interaction ComPPI
ABCE1 DDX18 25348397 N/A physical interaction ComPPI
ABCE1 NDUFA4 25348397 N/A physical interaction ComPPI
ABCE1 PPP6C 25348397 N/A physical interaction ComPPI
ABCE1 SURF4 25348397 N/A physical interaction ComPPI
ABCE1 ARPC5 25348397 N/A physical interaction ComPPI
ABCE1 EPB41L2 25348397 N/A physical interaction ComPPI
ABCE1 DKC1 25348397 N/A physical interaction ComPPI
ABCE1 PSIP1 25348397 N/A physical interaction ComPPI
ABCE1 RP2 25348397 N/A physical interaction ComPPI
ABCE1 FLOT1 25348397 N/A physical interaction ComPPI
ABCE1 UFL1 25348397 N/A physical interaction ComPPI
ABCE1 AIFM1 25348397 N/A physical interaction ComPPI
ABCE1 CSTB 25348397 N/A physical interaction ComPPI
ABCE1 TP53 25348397 N/A physical interaction ComPPI
ABCE1 FYN 25348397 N/A physical interaction ComPPI
ABCE1 HEXB 25348397 N/A physical interaction ComPPI
ABCE1 CTSA 25348397 N/A physical interaction ComPPI
ABCE1 IGF2R 25348397 N/A physical interaction ComPPI
ABCE1 SLC25A4 25348397 N/A physical interaction ComPPI
ABCE1 GLB1 25348397 N/A physical interaction ComPPI
ABCE1 RPL35A 25348397 N/A physical interaction ComPPI
ABCE1 SRM 25348397 N/A physical interaction ComPPI
ABCE1 LMNB1 25348397 N/A physical interaction ComPPI
ABCE1 SDHB 25348397 N/A physical interaction ComPPI
ABCE1 FBL 25348397 N/A physical interaction ComPPI
ABCE1 ACAT1 25348397 N/A physical interaction ComPPI
ABCE1 RPS12 25348397 N/A physical interaction ComPPI
ABCE1 PSMA2 25348397 N/A physical interaction ComPPI
ABCE1 MSN 25348397 N/A physical interaction ComPPI
ABCE1 APEX1 25348397 N/A physical interaction ComPPI
ABCE1 GNA11 25348397 N/A physical interaction ComPPI
ABCE1 PSMC2 25348397 N/A physical interaction ComPPI
ABCE1 TMPO 25348397 N/A physical interaction ComPPI
ABCE1 RPS27 25348397 N/A physical interaction ComPPI
ABCE1 VDAC2 25348397 N/A physical interaction ComPPI
ABCE1 RPL21 25348397 N/A physical interaction ComPPI
ABCE1 MAP1B 25348397 N/A physical interaction ComPPI
ABCE1 CACNA2D1 25348397 N/A physical interaction ComPPI
ABCE1 AK2 25348397 N/A physical interaction ComPPI
ABCE1 S100A10 25348397 N/A physical interaction ComPPI
ABCE1 HSPE1 25348397 N/A physical interaction ComPPI
ABCE1 RPS29 25348397 N/A physical interaction ComPPI
ABCE1 GNB1 25348397 N/A physical interaction ComPPI
ABCE1 ANK2 25348397 N/A physical interaction ComPPI
ABCE1 LMNB2 25348397 N/A physical interaction ComPPI
ABCE1 YWHAH 25348397 N/A physical interaction ComPPI
ABCE1 TWF1 25348397 N/A physical interaction ComPPI
ABCE1 DSG2 25348397 N/A physical interaction ComPPI
ABCE1 SMC1A 25348397 N/A physical interaction ComPPI
ABCE1 NUMA1 25348397 N/A physical interaction ComPPI
ABCE1 EBP 25348397 N/A physical interaction ComPPI
ABCE1 TOMM20 25348397 N/A physical interaction ComPPI
ABCE1 SF3A1 25348397 N/A physical interaction ComPPI
ABCE1 NDUFA5 25348397 N/A physical interaction ComPPI
ABCE1 AIF1L 25348397 N/A physical interaction ComPPI
ABCE1 ULBP3 25348397 N/A physical interaction ComPPI
ABCE1 DDX46 25348397 N/A physical interaction ComPPI
ABCE1 PEG10 25348397 N/A physical interaction ComPPI
ABCE1 GAS2L3 25348397 N/A physical interaction ComPPI
ABCE1 GADD45GIP1 25348397 N/A physical interaction ComPPI
ABCE1 CIP2A 25348397 N/A physical interaction ComPPI
ABCE1 HM13 25348397 N/A physical interaction ComPPI
ABCE1 MAIP1 25348397 N/A physical interaction ComPPI
ABCE1 ATXN2L 25348397 N/A physical interaction ComPPI
ABCE1 MACF1 25348397 N/A physical interaction ComPPI
ABCE1 SDF4 25348397 N/A physical interaction ComPPI
ABCE1 CPVL 25348397 N/A physical interaction ComPPI
ABCE1 GNB4 25348397 N/A physical interaction ComPPI
ABCE1 EXOSC4 25348397 N/A physical interaction ComPPI
ABCE1 YAE1 25348397 N/A physical interaction ComPPI
ABCE1 SMC4 25348397 N/A physical interaction ComPPI
ABCE1 MDN1 25348397 N/A physical interaction ComPPI
ABCE1 FANCI 25348397 N/A physical interaction ComPPI
ABCE1 TECR 25348397 N/A physical interaction ComPPI
ABCE1 CISD1 25348397 N/A physical interaction ComPPI
ABCE1 NDUFA13 25348397 N/A physical interaction ComPPI
ABCE1 STARD9 25348397 N/A physical interaction ComPPI
ABCE1 ATXN10 25348397 N/A physical interaction ComPPI
ABCE1 CPSF3 25348397 N/A physical interaction ComPPI
ABCE1 RPL36 25348397 N/A physical interaction ComPPI
ABCE1 SUPT16H 25348397 N/A physical interaction ComPPI
ABCE1 PTER 25348397 N/A physical interaction ComPPI
ABCE1 RPL7 25348397 N/A physical interaction ComPPI
ABCE1 VAPB 25348397 N/A physical interaction ComPPI
ABCE1 RPL4 25348397 N/A physical interaction ComPPI
ABCE1 POC5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ABCE1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ABCE1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ABCE1 CENPJ 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ABCE1 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ABCE1 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ABCE1 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
ABCE1 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
ABCE1 EIF3J 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABCE1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPS25 ABCE1 25348397 N/A physical interaction ComPPI
CBX5 ABCE1 25348397 N/A physical interaction ComPPI
PSMB3 ABCE1 25348397 N/A physical interaction ComPPI
EIF4A3 ABCE1 25348397 N/A physical interaction ComPPI
RTRAF ABCE1 25348397 N/A physical interaction ComPPI
GNAZ ABCE1 25348397 N/A physical interaction ComPPI
PNP ABCE1 25348397 N/A physical interaction ComPPI
CBR3 ABCE1 25348397 N/A physical interaction ComPPI
DCXR ABCE1 25348397 N/A physical interaction ComPPI
H3-5 ABCE1 25348397 N/A physical interaction ComPPI
HSCB ABCE1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

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