GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ACTR10
FullNmae
actin related protein 10
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:17372
EnsembleID
ENSG00000131966
Uniprot
Q9NZ32
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ACTR10
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
ACTR10
GO:0005515,GO:0005576,GO:0005829,GO:0005869,GO:0035578,GO:0098958,GO:1904115,GO:1904813
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
E2F4
ACTR10
17531812
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
ETS1
ACTR10
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
AR
ACTR10
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SMARCA4
ACTR10
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
ACTR10
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
ACTR10
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00002152A8
ACTR10
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS0000065FDF
ACTR10
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000045DBD
ACTR10
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003758F0
ACTR10
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
KRT31
ACTR10
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
ORC6
ACTR10
25348397
N/A
physical interaction
ComPPI
UQCRH
ACTR10
25348397
N/A
physical interaction
ComPPI
RHOC
ACTR10
25348397
N/A
physical interaction
ComPPI
ACTR10
ACTA1
12857853
14525934
25348397
N/A
experimental interaction detection,in vitro
ComPPI,HPRD
ACTR10
DCTN4
25348397
N/A
physical interaction
ComPPI
ACTR10
ACTR1A
25348397
N/A
physical interaction
ComPPI
ACTR10
ACTR1B
25348397
N/A
physical interaction
ComPPI
ACTR10
DCTN2
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
ACTR10
DCTN3
25348397
N/A
physical interaction
ComPPI
ACTR10
LMNB1
25348397
N/A
physical interaction
ComPPI
ACTR10
RABEP1
25348397
N/A
physical interaction
ComPPI
ACTR10
NAGK
24234451
25348397
25416956
physical association
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
ACTR10
CAPZA2
25348397
N/A
physical interaction
ComPPI
ACTR10
GPS2
25348397
N/A
physical interaction
ComPPI
ACTR10
DCTN1
24234451
25348397
26638075
27173435
association,physical association
physical interaction,tandem affinity purification,proximity-dependent biotin identification,inference by socio-affinity scoring
ComPPI,IntAct
ACTR10
KIF11
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ACTR10
DCTN6
25348397
N/A
physical interaction
ComPPI
ACTR10
RIC8A
25348397
N/A
physical interaction
ComPPI
ACTR10
PDGFD
25348397
N/A
physical interaction
ComPPI
ACTR10
MAPK8IP3
25348397
N/A
physical interaction
ComPPI
ACTR10
NGEF
25348397
N/A
physical interaction
ComPPI
ACTR10
BCL7C
25348397
N/A
physical interaction
ComPPI
ACTR10
EZR
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
RPS19BP1
ACTR10
25348397
N/A
physical interaction
ComPPI
RXFP4
ACTR10
24234451
28298427
physical association
ubiquitin reconstruction
IntAct
Source
Target
Pmid
Interactiontype
Methods
Database
URS00009AF97D
ACTR10
27087310
direct interaction,inhibition
N/A
NPInter
Visualization