Gene Information gene info

GENE:ACTR10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACTR10
FullNmae actin related protein 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17372
EnsembleID ENSG00000131966
Uniprot Q9NZ32

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACTR10 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
ACTR10 GO:0005515,GO:0005576,GO:0005829,GO:0005869,GO:0035578,GO:0098958,GO:1904115,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACTR10 hsa:55860 path:hsa04814 Motor proteins - Homo sapiens (human)
ACTR10 hsa:55860 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
ACTR10 hsa:55860 path:hsa05016 Huntington disease - Homo sapiens (human)
ACTR10 hsa:55860 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
ACTR10 hsa:55860 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 ACTR10 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ACTR10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
AR ACTR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 ACTR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACTR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACTR10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 ACTR10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065FDF ACTR10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD ACTR10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 ACTR10 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRT31 ACTR10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ORC6 ACTR10 25348397 N/A physical interaction ComPPI
UQCRH ACTR10 25348397 N/A physical interaction ComPPI
RHOC ACTR10 25348397 N/A physical interaction ComPPI
ACTR10 ACTA1 12857853 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ACTR10 DCTN4 25348397 N/A physical interaction ComPPI
ACTR10 ACTR1A 25348397 N/A physical interaction ComPPI
ACTR10 ACTR1B 25348397 N/A physical interaction ComPPI
ACTR10 DCTN2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ACTR10 DCTN3 25348397 N/A physical interaction ComPPI
ACTR10 LMNB1 25348397 N/A physical interaction ComPPI
ACTR10 RABEP1 25348397 N/A physical interaction ComPPI
ACTR10 NAGK 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ACTR10 CAPZA2 25348397 N/A physical interaction ComPPI
ACTR10 GPS2 25348397 N/A physical interaction ComPPI
ACTR10 DCTN1 24234451 25348397 26638075 27173435 association,physical association physical interaction,tandem affinity purification,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,IntAct
ACTR10 KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTR10 DCTN6 25348397 N/A physical interaction ComPPI
ACTR10 RIC8A 25348397 N/A physical interaction ComPPI
ACTR10 PDGFD 25348397 N/A physical interaction ComPPI
ACTR10 MAPK8IP3 25348397 N/A physical interaction ComPPI
ACTR10 NGEF 25348397 N/A physical interaction ComPPI
ACTR10 BCL7C 25348397 N/A physical interaction ComPPI
ACTR10 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPS19BP1 ACTR10 25348397 N/A physical interaction ComPPI
RXFP4 ACTR10 24234451 28298427 physical association ubiquitin reconstruction IntAct

Source Target Pmid Interactiontype Methods Database
URS00009AF97D ACTR10 27087310 direct interaction,inhibition N/A NPInter

Visualization