GENE：ADGRE5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ADGRE5 |
| FullNmae | adhesion G protein-coupled receptor E5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1711 |
| EnsembleID | ENSG00000123146 |
| Uniprot | P48960 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ADGRE5 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ADGRE5 | cuproptosis | 37243753 | However, there are very few studies of cuproptosis in GC. In this paper, a prediction model related to cuproptosis was established and verified through data mining, and the six genes related to cuproptosis were ACLY, FGD6, SERPINE1, SPATA13, RANGAP1, and ADGRE5. | genes related to cuproptosis |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ADGRE5 | GO:0004888,GO:0004930,GO:0005509,GO:0005515,GO:0005886,GO:0005925,GO:0006954,GO:0006955,GO:0007155,GO:0007166,GO:0007186,GO:0007189,GO:0007267,GO:0016020,GO:0030667,GO:0070062 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ADGRE5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | ADGRE5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ADGRE5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ADGRE5 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SP1 | ADGRE5 | 18329191 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| SP3 | ADGRE5 | 18329191 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| SMARCA4 | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | ADGRE5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | ADGRE5 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | ADGRE5 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00005651EE | ADGRE5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001D69F6 | ADGRE5 | 24274104 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS000053B1E8 | ADGRE5 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237E04 | ADGRE5 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A9FB9 | ADGRE5 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | ADGRE5 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YIPF3 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| HMOX1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| SRC | ADGRE5 | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| TPST1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| TFAP2C | ADGRE5 | 24234451 24835590 25348397 | physical association | two hybrid | ComPPI,IntAct |
| XRN1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| NAGPA | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPD | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| GNB2 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| SLC29A1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| BET1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| KNL1 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| NRAS | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | ADGRE5 | 10540231 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| ADGRE5 | LPAR1 | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | GOLT1B | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | ADARB1 | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | MT-ND5 | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | NDUFB8 | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | VDAC3 | 25348397 | N/A | physical interaction | ComPPI |
| ADGRE5 | EXTL3 | 25348397 | N/A | physical interaction | ComPPI |
| BACE2 | ADGRE5 | 25348397 | N/A | physical interaction | ComPPI |
| SP1 | ADGRE5 | 18329191 27898060 | stimulant | N/A | OmniPath |
| CD55 | ADGRE5 | 10540231 12417446 27898060 | stimulant | N/A | OmniPath |