GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ANKRD49
FullNmae
ankyrin repeat domain 49
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:25970
EnsembleID
ENSG00000168876
Uniprot
Q8WVL7
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ANKRD49
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
ANKRD49
GO:0005515,GO:0005634,GO:0007283,GO:0030154,GO:0045893,GO:0045893
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
SMARCA4
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
ETS1
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
ANKRD49
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000148B91
ANKRD49
23689423
25416803
mrna cleavage,inhibition
array technology,quantitative reverse transcription pcr
TarBase
URS00003003B4
ANKRD49
22012620
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002AA55A
ANKRD49
22012620
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000170CF4
ANKRD49
22012620
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
RAN
ANKRD49
24234451
24855949
25348397
physical association
pull down
ComPPI,IntAct
CSNK1D
ANKRD49
25348397
N/A
physical interaction
ComPPI
SMARCD1
ANKRD49
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
CSNK1E
ANKRD49
25348397
N/A
physical interaction
ComPPI
HIF1AN
ANKRD49
17003112
24234451
25348397
29426014
hydroxylation reaction,association
anti tag coimmunoprecipitation,hydroxylation reaction,physical interaction,hydroxylase assay
ComPPI,IntAct
SHMT2
ANKRD49
25348397
N/A
physical interaction
ComPPI
NXF1
ANKRD49
25348397
N/A
physical interaction
ComPPI
MOV10
ANKRD49
25348397
N/A
physical interaction
ComPPI
Visualization