GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
AOC2
FullNmae
amine oxidase copper containing 2
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:549
EnsembleID
ENSG00000131480
Uniprot
O75106
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
AOC2
mitotic_cd
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
AOC2
cuproptosis
38403151
Further analysis resulted in the identification of 6 CRGs, namely LOX, SPARC, MOXD1, ALB, MT-CO2, and AOC2.
cuproptosis-related genes (CRGs)
AOC2
cuproptosis
36313717
The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1.
Genes related to copper homeostasis pathway
Go Annotation:
GeneSymbol
Go id
AOC2
GO:0005507,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0006584,GO:0006805,GO:0007601,GO:0008131,GO:0008131,GO:0009055,GO:0009308,GO:0022900,GO:0048038,GO:0052593,GO:0052594,GO:0052596
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
YBX1
AOC2
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
CTCF
AOC2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
AOC2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F2
AOC2
N/A
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
LEMD3
AOC2
25348397
N/A
physical interaction
ComPPI
SHMT2
AOC2
25348397
N/A
physical interaction
ComPPI
MOV10
AOC2
25348397
N/A
physical interaction
ComPPI
Visualization