Gene Information gene info

GENE:AOC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AOC2
FullNmae amine oxidase copper containing 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:549
EnsembleID ENSG00000131480
Uniprot O75106

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AOC2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AOC2 cuproptosis 38403151 Further analysis resulted in the identification of 6 CRGs, namely LOX, SPARC, MOXD1, ALB, MT-CO2, and AOC2. cuproptosis-related genes (CRGs)
AOC2 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. Genes related to copper homeostasis pathway

Go Annotation:

GeneSymbol Go id
AOC2 GO:0005507,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0006584,GO:0006805,GO:0007601,GO:0008131,GO:0008131,GO:0009055,GO:0009308,GO:0022900,GO:0048038,GO:0052593,GO:0052594,GO:0052596

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AOC2 hsa:314 path:hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)
AOC2 hsa:314 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
AOC2 hsa:314 path:hsa00360 Phenylalanine metabolism - Homo sapiens (human)
AOC2 hsa:314 path:hsa00410 beta-Alanine metabolism - Homo sapiens (human)
AOC2 hsa:314 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 AOC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF AOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AOC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 AOC2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
LEMD3 AOC2 25348397 N/A physical interaction ComPPI
SHMT2 AOC2 25348397 N/A physical interaction ComPPI
MOV10 AOC2 25348397 N/A physical interaction ComPPI

Visualization