Gene Information gene info

GENE:API5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol API5
FullNmae apoptosis inhibitor 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:594
EnsembleID ENSG00000166181
Uniprot Q9BZZ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
API5 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
API5 GO:0003723,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005681,GO:0005737,GO:0016020,GO:0016607,GO:0017134,GO:0043066,GO:0043066,GO:0043066,GO:0043066,GO:0044346,GO:2000270

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 API5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 API5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000184017 API5 N/A 18319255 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000184017 API5 18319255 22328513 22743998 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS0000345DEB API5 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000032FC1A API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 API5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 API5 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 API5 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L API5 25348397 N/A physical interaction ComPPI
GLRX3 API5 25348397 N/A physical interaction ComPPI
OXSR1 API5 25348397 N/A physical interaction ComPPI
BAG3 API5 25348397 N/A physical interaction ComPPI
IMPDH2 API5 25348397 N/A physical interaction ComPPI
TP53BP1 API5 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MCM5 API5 25348397 N/A physical interaction ComPPI
DCUN1D1 API5 25348397 N/A physical interaction ComPPI
RAD21 API5 25348397 N/A physical interaction ComPPI
EZH2 API5 25348397 N/A physical interaction ComPPI
DLD API5 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 API5 25348397 N/A physical interaction ComPPI
XRN2 API5 25348397 N/A physical interaction ComPPI
LASP1 API5 25348397 N/A physical interaction ComPPI
EIF6 API5 25348397 N/A physical interaction ComPPI
PPP2R5C API5 25348397 N/A physical interaction ComPPI
EWSR1 API5 25348397 N/A physical interaction ComPPI
PPP2R5E API5 25348397 N/A physical interaction ComPPI
EGFR API5 25348397 N/A physical interaction ComPPI
HTT API5 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
STAT6 API5 25348397 N/A physical interaction ComPPI
EED API5 25348397 N/A physical interaction ComPPI
H3C1 API5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STK39 API5 25348397 N/A physical interaction ComPPI
TRIM25 API5 25348397 N/A physical interaction ComPPI
ACIN1 API5 19387494 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct,OmniPath
ELAVL1 API5 25348397 N/A physical interaction ComPPI
MLH1 API5 25348397 N/A physical interaction ComPPI
DDX39A API5 25348397 N/A physical interaction ComPPI
SOD1 API5 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRKAB1 API5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GTF3C4 API5 25348397 N/A physical interaction ComPPI
FGF2 API5 11075807 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
EHD1 API5 25348397 N/A physical interaction ComPPI
CCND2 API5 25348397 N/A physical interaction ComPPI
DRG2 API5 25348397 N/A physical interaction ComPPI
POU5F1 API5 25348397 N/A physical interaction ComPPI
API5 ADSL 25348397 N/A physical interaction ComPPI
API5 TTI1 25348397 N/A physical interaction ComPPI
API5 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
EBNA1BP2 API5 25348397 N/A physical interaction ComPPI
API5 SOCS6 24234451 30021884 physical association cross-linking study IntAct
DDX39B API5 24234451 30021884 physical association cross-linking study IntAct
API5 LTV1 24234451 30021884 physical association cross-linking study IntAct

Visualization