GENE:ATF4
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | ATF4 |
FullNmae | activating transcription factor 4 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:786 |
EnsembleID | ENSG00000128272 |
Uniprot | P18848 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
ATF4 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
ATF4 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
ATF4 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
ATF4 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
ATF4 | cuproptosis | 38150993 | Mechanically, knockdown of ATF4 facilitated the DSF/Cu-induced cell death and exacerbated the generation of lipid peroxides under the challenge of DSF/Cu. | Inhibitor |
Go Annotation:
GeneSymbol | Go id |
---|---|
ATF4 | GO:0000122,GO:0000785,GO:0000976,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0003677,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005813,GO:0006094,GO:0006355,GO:0006357,GO:0006357,GO:0006366,GO:0006874,GO:0007214,GO:0008140,GO:0009636,GO:0010575,GO:0010628,GO:0016607,GO:0019901,GO:0030182,GO:0030282,GO:0030968,GO:0031667,GO:0032057,GO:0032590,GO:0032922,GO:0032991,GO:0034198,GO:0034399,GO:0034599,GO:0034644,GO:0034976,GO:0034976,GO:0035162,GO:0036003,GO:0036091,GO:0036091,GO:0036499,GO:0036499,GO:0042149,GO:0042789,GO:0042802,GO:0043005,GO:0043065,GO:0043267,GO:0043522,GO:0043525,GO:0043565,GO:0045667,GO:0045893,GO:0045893,GO:0045893,GO:0045893,GO:0045943,GO:0045944,GO:0045944,GO:0045944,GO:0045944,GO:0046982,GO:0048167,GO:0061629,GO:0070059,GO:0070169,GO:0070309,GO:0070982,GO:0090575,GO:0090650,GO:0120163,GO:0140296,GO:0140467,GO:0140467,GO:0140468,GO:1903377,GO:1905461,GO:1990037,GO:1990253,GO:1990440,GO:1990440,GO:1990589,GO:1990589,GO:1990590,GO:1990590,GO:1990617,GO:1990617,GO:1990617,GO:1990737,GO:1990837,GO:1990841,GO:2000120 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
ATF4 | hsa:468 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04137 | Mitophagy - animal - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04210 | Apoptosis - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04211 | Longevity regulating pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04261 | Adrenergic signaling in cardiomyocytes - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04668 | TNF signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04720 | Long-term potentiation - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04722 | Neurotrophin signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04725 | Cholinergic synapse - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04728 | Dopaminergic synapse - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04911 | Insulin secretion - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04912 | GnRH signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04915 | Estrogen signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04918 | Thyroid hormone synthesis - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04922 | Glucagon signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04925 | Aldosterone synthesis and secretion - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04926 | Relaxin signaling pathway - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04927 | Cortisol synthesis and secretion - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04928 | Parathyroid hormone synthesis, secretion and action - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04932 | Non-alcoholic fatty liver disease - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04934 | Cushing syndrome - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa04935 | Growth hormone synthesis, secretion and action - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05012 | Parkinson disease - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05014 | Amyotrophic lateral sclerosis - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05020 | Prion disease - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05030 | Cocaine addiction - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05031 | Amphetamine addiction - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05034 | Alcoholism - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05207 | Chemical carcinogenesis - receptor activation - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05215 | Prostate cancer - Homo sapiens (human) |
ATF4 | hsa:468 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EIF2S1 | ATF4 | 12601012 12667446 16246152 23850759 26192618 | interaction type | N/A | ACSN |
EIF2S2 | ATF4 | 12601012 12667446 16246152 23850759 26192618 | interaction type | N/A | ACSN |
EIF2S3 | ATF4 | 12601012 12667446 16246152 23850759 26192618 | interaction type | N/A | ACSN |
NDUFA1 | ATF4 | 12601012 12667446 16246152 23850759 26192618 | interaction type | N/A | ACSN |
ATF4 | XIAP | 23850759 26192618 26587781 | interaction type | N/A | ACSN |
ATF3 | ATF4 | 23850759 26192618 26587781 | interaction type | N/A | ACSN |
ATF4 | ATF1 | 23180781 9417115 | physical association | electrophoretic mobility supershift assay | InnateDB |
ATF4 | IL2 | 23180781 9417115 | physical association | electrophoretic mobility supershift assay | InnateDB |
ATF4 | REL | 23180781 9417115 | physical association | electrophoretic mobility supershift assay | InnateDB |
ATF4 | BTRC | 18052253 23180781 25416956 | physical association | two hybrid,nuclear magnetic resonance | InnateDB |
ATF4 | TRIB3 | 18408768 23180781 25416956 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
ATF4 | MAP1LC3B | 20038797 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ATF4 | DDIT3 | 20038797 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ATF4 | EGR1 | 19374776 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ATF4 | ASNS | 18840095 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ATF4 | CEBPG | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | GOLGA1 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | GPS2 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | BFSP2 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | NDC80 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | LDOC1 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | CCDC106 | 23180781 25416956 | physical association | two hybrid | InnateDB |
ATF4 | GCC1 | 23180781 25416956 | physical association | two hybrid | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | ATF4 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | ATF4 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
ETS1 | ATF4 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | ATF4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
MYC | ATF4 | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
VDR | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | ATF4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HDAC4 | ATF4 | 24308964 | trascriptional regulation,stimulation | inferred by curator | TFlink |
IRF7 | ATF4 | 21148039 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIB3 | ATF4 | 15781252 17707795 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000160683 | ATF4 | 23223004 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS0000160683 | ATF4 | 23223004 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
URS000052E1A6 | ATF4 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000148B91 | ATF4 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
RET | ATF4 | 22135298 | phosphorylation | N/A | PhosphoSite |
RPS6KA3 | ATF4 | 22135298 | phosphorylation | N/A | PhosphoSite |
ATF2 | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | ATF2 | 25361965 | interaction type | N/A | PTMCode2 |
CEBPB | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | CEBPB | 25361965 | interaction type | N/A | PTMCode2 |
DAPK3 | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | DAPK3 | 25361965 | interaction type | N/A | PTMCode2 |
CEBPG | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | CEBPG | 25361965 | interaction type | N/A | PTMCode2 |
FOS | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | FOS | 25361965 | interaction type | N/A | PTMCode2 |
POLR2C | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | POLR2C | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | ATF3 | 25361965 | interaction type | N/A | PTMCode2 |
ATF3 | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | BTRC | 25361965 | interaction type | N/A | PTMCode2 |
BTRC | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | JUN | 25361965 | interaction type | N/A | PTMCode2 |
JUN | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | NFE2L2 | 25361965 | interaction type | N/A | PTMCode2 |
NFE2L2 | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | RELA | 25361965 | interaction type | N/A | PTMCode2 |
RELA | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | GABBR1 | 25361965 | interaction type | N/A | PTMCode2 |
GABBR1 | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
ATF4 | EIF2A | 25361965 | interaction type | N/A | PTMCode2 |
EIF2A | ATF4 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
GCC1 | ATF4 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
TTR | ATF4 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
NDC80 | ATF4 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
SNAP29 | ATF4 | 21988832 24234451 25348397 26359495 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
LDOC1 | ATF4 | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | CEBPG | 1371974 14525934 20102225 24234451 25348397 25416956 | physical association | two hybrid,experimental interaction detection,peptide array,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid | ComPPI,HPRD,IntAct |
ATF4 | BFSP2 | 24234451 25348397 25416956 25910212 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
ATF4 | GOLGA1 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ATF4 | TRIB3 | 12743605 14525934 24234451 25348397 25416956 25910212 | physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | CCDC106 | 14525934 16169070 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | JUN | 14525934 1827203 20936779 24234451 25241761 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
ATF4 | CEBPB | 11018027 14525934 20102225 24234451 25348397 27898060 | N/A | experimental interaction detection,peptide array,in vitro | ComPPI,HPRD,IntAct,OmniPath |
ATF4 | GTF2F2 | 14525934 25348397 9295363 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
ATF4 | NFE2L2 | 11274184 14525934 24234451 25348397 26700459 27898060 | association,physical association | two hybrid,experimental interaction detection,physical interaction,chromatin immunoprecipitation assay,in vitro,in vivo,proximity ligation assay,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
ATF4 | DAPK3 | 14525934 21408167 24234451 25348397 9488481 | physical association | anti tag coimmunoprecipitation,experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,IntAct |
ATF4 | GABBR2 | 11087824 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
ATF4 | POLR2C | 12860379 14525934 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | TREX2 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
ATF4 | PTCD3 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | GPS2 | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | DDIT3 | 12805554 14525934 18330356 20102225 24234451 25348397 | physical association | two hybrid,experimental interaction detection,peptide array,physical interaction,in vitro | ComPPI,HPRD,IntAct |
ATF4 | NFE2L1 | 11025215 14525934 20102225 24234451 25348397 27898060 | N/A | two hybrid,experimental interaction detection,peptide array,in vitro,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
ATF4 | EIF2A | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | TBP | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | GTF2B | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | CREBBP | 24234451 25241761 25348397 | physical association | physical interaction,proximity ligation assay | ComPPI,IntAct |
ATF4 | ATF3 | 19164757 20102225 23661758 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,peptide array,physical interaction,electrophoretic mobility shift assay | ComPPI,IntAct,OmniPath |
ATF4 | DISC1 | 12812986 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | GABBR1 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | EP300 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | BTRC | 11238952 21988832 24234451 25348397 25416956 26871637 | colocalization,physical association | anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,confocal microscopy,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ATF4 | ZNF234 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | ZNF226 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | TRIM24 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | GTF2A1L | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | KAT2B | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | CEBPE | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | FBXW11 | 20724472 22017875 25332235 25348397 25515538 27898060 | N/A | physical interaction | ComPPI,OmniPath |
ATF4 | EGLN3 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | APP | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | ZNF212 | 18255255 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ATF4 | NFKBIA | 18255255 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ATF4 | SRA1 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | HAUS7 | 14525934 16189514 19447967 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
ATF4 | NFE2 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | MAFB | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | MAF | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
ATF4 | BATF3 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | BATF2 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | BATF | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
ATF4 | FOSL1 | 25348397 | N/A | coimmunoprecipitation,physical interaction,physical interaction | ComPPI |
ATF4 | FOS | 20102225 24234451 25241761 25348397 | physical association | coimmunoprecipitation,peptide array,physical interaction,proximity ligation assay | ComPPI,IntAct |
ATF4 | CEBPA | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
ATF4 | CREBZF | 16343488 20102225 24234451 25348397 | physical association | anti bait coimmunoprecipitation,peptide array,protein complementation assay,pull down,physical interaction | ComPPI,IntAct |
ATF4 | CREB3 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | APH1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | MPZL2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | TGM2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ATF4 | REPS1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ATF4 | RPS6 | 21988832 24234451 25348397 | colocalization,physical association | two hybrid,physical interaction,confocal microscopy | ComPPI,IntAct |
ATF4 | HK3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | LMNB1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | MDM2 | 21988832 24234451 25348397 | colocalization,physical association | two hybrid,physical interaction,confocal microscopy | ComPPI,IntAct |
ATF4 | MAP2K7 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | CKAP4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ATF4 | ASB7 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
ATF4 | NEK6 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | DNMT3L | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | NLGN3 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | TBC1D25 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | GOLGA8F | 24234451 25348397 25416956 | physical association | two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ATF4 | GOLGA8DP | 24234451 25348397 25416956 | physical association | two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ATF4 | CEBPD | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
ATF4 | NFE2L3 | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
ATF4 | AP1M1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ATF4 | SAPCD2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ATF4 | JDP2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ATF4 | TARS3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ATF4 | NAP1L5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
JUNB | ATF4 | 21988832 24234451 25348397 | colocalization,physical association | two hybrid,physical interaction,confocal microscopy | ComPPI,IntAct |
ATF2 | ATF4 | 25348397 | N/A | physical interaction | ComPPI |
ATF4 | ATF4 | 16343488 24234451 | N/A | pull down | IntAct |
ATF4 | HYOU1 | 24234451 26700459 | association | chromatin immunoprecipitation assay | IntAct |
ATF4 | KTN1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
ATF4 | ABRAXAS2 | 22974638 27898060 | N/A | N/A | OmniPath |
EIF2AK3 | ATF4 | 15550948 19029953 27898060 | stimulant | N/A | OmniPath |
RET | ATF4 | 25795775 27898060 | N/A | N/A | OmniPath |
ATF4 | ULK1 | 23078367 27898060 | N/A | N/A | OmniPath |
ATF4 | MAP1LC3B | 20038797 27898060 | N/A | N/A | OmniPath |
EIF2A | ATF4 | 18471544 27898060 | stimulant | N/A | OmniPath |
DDIT3 | ATF4 | 12805554 18330356 20038797 20102225 23661758 27898060 | N/A | N/A | OmniPath |
ATF4 | FUS | 18471544 27898060 | stimulant | N/A | OmniPath |
ATF4 | TRIB3 | 12743605 18276110 25416956 27898060 | N/A | N/A | OmniPath |
TRIB3 | ATF4 | 12743605 18276110 25416956 27898060 | N/A | N/A | OmniPath |
RPS6KA3 | ATF4 | 15109498 22052162 23975372 27898060 | stimulant | N/A | OmniPath |
RPS6KA2 | ATF4 | 11238952 15109498 27898060 | stimulant | N/A | OmniPath |
ATF4 | ATG5 | 20038797 27898060 | N/A | N/A | OmniPath |
BTRC | ATF4 | 11238952 16219772 18052253 19053519 21516116 21988832 25416956 26091241 27898060 | N/A | N/A | OmniPath |
CEBPG | ATF4 | 1371974 20102225 23661758 25416956 27898060 | N/A | N/A | OmniPath |
ATF4 | LDOC1 | 16189514 25416956 27898060 | N/A | N/A | OmniPath |
CCDC106 | ATF4 | 16169070 25416956 27898060 | N/A | N/A | OmniPath |
ATF4 | GPS2 | 16189514 25416956 27898060 | N/A | N/A | OmniPath |