GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ATL2
FullNmae
atlastin GTPase 2
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:24047
EnsembleID
ENSG00000119787
Uniprot
Q8NHH9
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ATL2
mitotic_cd
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
ATL2
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
ATL2
GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005783,GO:0007029,GO:0007029,GO:0007030,GO:0016020,GO:0016020,GO:0042802,GO:0051260,GO:0051260,GO:0098826,GO:1990809
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
ATL2
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA1
ATL2
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
GATA2
ATL2
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
ATL2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000338542
ATL2
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS000021D7C8
ATL2
20371350
25416803
mrna cleavage,inhibition
nucleotide sequence identification
TarBase
URS00001F0C23
ATL2
20371350
25416803
mrna cleavage,inhibition
nucleotide sequence identification
TarBase
URS0000170CF4
ATL2
20371350
25416803
mrna cleavage,inhibition
nucleotide sequence identification
TarBase
URS0000065D58
ATL2
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS00005651EE
ATL2
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS0000568FF8
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075D814
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075CC78
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00004F859B
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00001012BC
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000021202F
ATL2
23313552
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000100748
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002373FD
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00000AD002
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000076E54
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00004CD810
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075C4B1
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002B0B46
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00004929F1
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002E728C
ATL2
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
CSNK1G2
ATL2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
DPEP1
ATL2
25348397
N/A
physical interaction
ComPPI
YWHAZ
ATL2
15161933
24234451
25348397
physical association
pull down
ComPPI,IntAct
NTRK1
ATL2
25348397
N/A
physical interaction
ComPPI
SMARCA4
ATL2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
LAMA1
ATL2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
STK39
ATL2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
CD79B
ATL2
25348397
N/A
physical interaction
ComPPI
COPG1
ATL2
25348397
N/A
physical interaction
ComPPI
ATL2
ADD1
25348397
N/A
physical interaction
ComPPI
ATL2
NELFA
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ATL2
FAM120A
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ATL2
KLHDC2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ATL2
ATL3
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ATL2
MAS1
25348397
N/A
physical interaction
ComPPI
ATL2
IL1R2
25348397
N/A
physical interaction
ComPPI
ATL2
CHRM3
25348397
N/A
physical interaction
ComPPI
ATL2
SLC15A1
25348397
N/A
physical interaction
ComPPI
ATL2
FPR2
25348397
N/A
physical interaction
ComPPI
SNRNP27
ATL2
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
Visualization