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GENE：ATP6AP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6AP1
FullNmae ATPase H+ transporting accessory protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:868
EnsembleID ENSG00000071553
Uniprot Q15904

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6AP1 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ATP6AP1 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ATP6AP1 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. Copper metabolism disease related genes

Go Annotation:

GeneSymbol Go id
ATP6AP1 GO:0000139,GO:0001671,GO:0005515,GO:0005765,GO:0005789,GO:0005886,GO:0006879,GO:0007035,GO:0007042,GO:0010008,GO:0010008,GO:0016020,GO:0016469,GO:0030641,GO:0030665,GO:0030672,GO:0031267,GO:0033116,GO:0033176,GO:0033176,GO:0036035,GO:0036295,GO:0048388,GO:0051452,GO:0061795,GO:0070062,GO:0097401,GO:0099638,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6AP1 hsa:537 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa04142 Lysosome - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05152 Tuberculosis - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05161 Hepatitis B - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6AP1 hsa:537 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 ATP6AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP6AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ATP6AP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002971AB ATP6AP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 ATP6AP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 ATP6AP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002EF20A ATP6AP1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 ATP6AP1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004C6C6F ATP6AP1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005BB0FD ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000035AC91 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001DA458 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003B6B84 ATP6AP1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBCK1 ATP6AP1 25361965 interaction type N/A PTMCode2
ATP6AP1 RBCK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HBA1 ATP6AP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ERBB2 ATP6AP1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PICK1 ATP6AP1 25348397 N/A physical interaction ComPPI
PTPRO ATP6AP1 25348397 N/A physical interaction ComPPI
RAB7A ATP6AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NR1I2 ATP6AP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CANX ATP6AP1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
EVC2 ATP6AP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK6 ATP6AP1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
ANG ATP6AP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ATP6AP2 ATP6AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SYVN1 ATP6AP1 25348397 N/A physical interaction ComPPI
HNRNPAB ATP6AP1 25348397 N/A physical interaction ComPPI
RHOU ATP6AP1 25348397 N/A physical interaction ComPPI
ATP6V0D1 ATP6AP1 25348397 N/A physical interaction ComPPI
ATP6AP1 FBXO6 25348397 N/A physical interaction ComPPI
ATP6AP1 MOV10 25348397 N/A physical interaction ComPPI
ATP6AP1 NXF1 25348397 N/A physical interaction ComPPI
ATP6AP1 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP1 TMEM67 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP1 DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6AP1 MYEF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6AP1 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6AP1 CTDNEP1 25348397 N/A physical interaction ComPPI
ATP6AP1 ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6AP1 KIAA2013 25348397 N/A physical interaction ComPPI
ATP6AP1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1C1 ATP6AP1 25348397 N/A physical interaction ComPPI

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