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GENE：BRPF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRPF1
FullNmae bromodomain and PHD finger containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14255
EnsembleID ENSG00000156983
Uniprot P55201

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRPF1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRPF1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
BRPF1 GO:0000123,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006338,GO:0006355,GO:0006357,GO:0010698,GO:0043995,GO:0043996,GO:0043997,GO:0045893,GO:0046872,GO:0050793,GO:0070776,GO:0070776,GO:1903706

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 BRPF1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 BRPF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 BRPF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 BRPF1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F1 BRPF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR BRPF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC BRPF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB BRPF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA BRPF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 BRPF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC4BD BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 BRPF1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 BRPF1 25348397 N/A physical interaction ComPPI
H2AC11 BRPF1 24234451 25281266 25348397 N/A isothermal titration calorimetry,x-ray crystallography ComPPI,IntAct
H4C1 BRPF1 24234451 25281266 25348397 N/A isothermal titration calorimetry,x-ray crystallography ComPPI,IntAct
XRCC1 BRPF1 25348397 N/A physical interaction ComPPI
XRCC5 BRPF1 25348397 N/A physical interaction ComPPI
MYC BRPF1 25348397 N/A physical interaction ComPPI
ARRB1 BRPF1 25348397 N/A physical interaction ComPPI
ARRB2 BRPF1 25348397 N/A physical interaction ComPPI
MPHOSPH8 BRPF1 25348397 N/A physical interaction ComPPI
H3C15 BRPF1 25348397 N/A physical interaction ComPPI
BRD2 BRPF1 25348397 N/A physical interaction ComPPI
ING4 BRPF1 25348397 N/A physical interaction ComPPI
ING5 BRPF1 25348397 N/A physical interaction ComPPI
H3C1 BRPF1 25348397 N/A physical interaction ComPPI
KIF2C BRPF1 25348397 N/A physical interaction ComPPI
MEAF6 BRPF1 25348397 N/A physical interaction ComPPI
KIF11 BRPF1 25348397 N/A physical interaction ComPPI
PIP4K2A BRPF1 25348397 N/A physical interaction ComPPI
KAT6A BRPF1 18469222 18794358 19001415 25348397 27898060 N/A physical interaction ComPPI,OmniPath

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